Summary for the 454-th Site(I) |
PID | QueryLength | FocusSite | TITLE |
27558 | 918 | 454 I | RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor; |
AC/ID | AC:P40189 ID:IL6RB_HUMAN |
Feature Table for 454-th site |
VARIANT: /note="I -> T (in dbSNP:rs2228046)" /id="VAR_047785" STRAND: VAR_SEQ: /note="Missing (in isoform 3)" /id="VSP_043716" DOMAIN: /note="Fibronectin type-III 4" VAR_SEQ: /note="Missing (in isoform 2)" /id="VSP_001685" TOPO_DOM: /note="Extracellular" VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951" CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899" |
VARIANT for 454-th site |
I->T LB/B dbSNP:rs2228046 " -" |
Percentages of Amino Acids in Homologous Proteins [show alignment] |
I:31% V:30% L:12% E:7% R:4% Q:3% F:3% G:2% K:2% M:2% P:2% S:2% |
Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
8d82 | E (beta-strand) | b (buried) | 0.0 |
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