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| PID | QueryLength | FocusSite | TITLE |
| 2752856 | 925 | 268 C | RecName: Full=Antiviral innate immune response receptor RIG-I ;AltName: Full=ATP-dependent RNA helicase DDX58 ; EC=3.6.4.13 ;AltName: Full=DEAD box protein 58;AltName: Full=RIG-I-like receptor 1; Short=RLR-1;AltName: Full=RNA sensor RIG-I ;AltName: Full=Retinoic acid-inducible gene 1 protein; Short=RIG-1;AltName: Full=Retinoic acid-inducible gene I protein; Short=RIG-I; |
| AC/ID | AC:O95786 ID:RIGI_HUMAN |
| Feature Table for 268-th site |
VARIANT: /note="C -> F (in SGMRT2; results in constitutive activation and enhanced interferon-mediated signaling; dbSNP:rs786204848)" /id="VAR_073667" BINDING: /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" DOMAIN: /note="Helicase ATP-binding" REGION: /note="Interaction with ZC3HAV1" CHAIN: /note="Antiviral innate immune response receptor RIG-I" /id="PRO_0000144093" |
| VARIANT for 268-th site |
C->F LP/P dbSNP:rs7862048 " Singleton-Merten syndrome 2 (SGMRT2) " [MIM:616298] |
Percentages of Amino Acids in Homologous Proteins
 [show alignment]
|
S:41% L:20% A:17% T:9% C:6% I:3% M:3% |
| Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
 8dvs |
S (bend) | b (buried) | 0.0 |
| Predicted Bind Molecules |
| compound:10 precipitant:10 |
| Templates for 3D complexes |
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compound [ADP ] 3zd7_A_1_F_1 4ay2_A_1_D_1 5e3h_A_1_I_1 7jl1_A_1_E_1 7jl3_A_1_I_1 7jl3_C_1_M_1 7jl3_E_1_Q_1 7to2_A_1_E_1 8dvs_A_1_E_1 8dvu_A_1_E_1
precipitant [SO4 ] 2ykg_A_1_E_1 4bpb_A_1_E_1 4on9_A_1_C_1 4on9_B_1_E_1 [ETF ] 5f9f_A_1_O_1 [BU3 ] 5f9f_C_1_W_1 5f9f_E_1_Z_1 5f9f_G_1_DA_1 5f9f_I_1_KA_1 5f9f_K_1_OA_1
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Summary for the 268-th Site(C)