Summary for the 270-th Site(K)
PID QueryLength FocusSite TITLE
2752856 925 270 K RecName: Full=Antiviral innate immune response receptor RIG-I ;AltName: Full=ATP-dependent RNA helicase DDX58 ; EC=3.6.4.13 ;AltName: Full=DEAD box protein 58;AltName: Full=RIG-I-like receptor 1; Short=RLR-1;AltName: Full=RNA sensor RIG-I ;AltName: Full=Retinoic acid-inducible gene 1 protein; Short=RIG-1;AltName: Full=Retinoic acid-inducible gene I protein; Short=RIG-I;
UniProt Information
AC/IDAC:O95786 ID:RIGI_HUMAN
Feature Table for 270-th site MUTAGEN: /note="K->A: No IRF3 signaling activity. Loss of dsRNA- induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway." ECO:0000269|PubMed:15708988, ECO:0000269|PubMed:19211564"
BINDING: /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616"
HELIX:
DOMAIN: /note="Helicase ATP-binding"
REGION: /note="Interaction with ZC3HAV1"
CHAIN: /note="Antiviral innate immune response receptor RIG-I" /id="PRO_0000144093"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
K:97%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8dvs H (alpha-helix) b (buried) 11.8
3D Complex Information
Predicted Bind Molecules
compound:8 metal:2 precipitant:13
Templates for 3D complexes
compound [ADP ] 5e3h_A_1_I_1 7jl1_A_1_E_1 7jl3_A_1_I_1 7jl3_C_1_M_1 7jl3_E_1_Q_1 7to2_A_1_E_1 8dvs_A_1_E_1 8dvu_A_1_E_1 metal [MG ] 5f9h_A_1_P_1 8dvs_A_1_D_1 precipitant [SO4 ] 4on9_A_1_C_1 4on9_B_1_E_1 [BEF ] 5e3h_A_1_J_1 [ETF ] 5f9f_A_1_O_1 [BU3 ] 5f9f_A_1_Q_1 5f9f_C_1_W_1 5f9f_E_1_Z_1 5f9f_G_1_DA_1 5f9f_I_1_KA_1 5f9f_K_1_OA_1 [ALF ] 7jl3_A_1_J_1 7jl3_C_1_N_1 7jl3_E_1_R_1


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