Summary for the 788-th Site(K)

PID QueryLength FocusSite TITLE
2752856 925 788 K RecName: Full=Antiviral innate immune response receptor RIG-I ;AltName: Full=ATP-dependent RNA helicase DDX58 ; EC=3.6.4.13 ;AltName: Full=DEAD box protein 58;AltName: Full=RIG-I-like receptor 1; Short=RLR-1;AltName: Full=RNA sensor RIG-I ;AltName: Full=Retinoic acid-inducible gene 1 protein; Short=RIG-1;AltName: Full=Retinoic acid-inducible gene I protein; Short=RIG-I;
UniProt Information
AC/IDAC:O95786 ID:RIGI_HUMAN
Feature Table for 788-th site MUTAGEN: /note="K->R: Decreased polyubiquitination. Loss of function in RIG-I signaling pathway. Decreased ubiquitination and function in RIG-I signaling pathway without effect on RNA- binding; when associated with R-849, R-851, R-888, R-907 and R-909."
HELIX:
REGION: /note="Mediates interaction with RNF135"
REGION: /note="Interaction with ZC3HAV1"
CHAIN: /note="Antiviral innate immune response receptor RIG-I" /id="PRO_0000144093"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
K:33% A:17% Q:12% V:11% R:10% I:6% L:6% G:1% S:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8dvs H (alpha-helix) b (buried) 18.4


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