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| PID | QueryLength | FocusSite | TITLE |
| 2692367 | 631 | 565 D | RecName: Full=Sphingomyelin phosphodiesterase ; EC=3.1.4.12 ; EC=3.1.4.3 ;AltName: Full=Acid sphingomyelinase ; Short=aSMase;Contains: RecName: Full=Sphingomyelin phosphodiesterase, processed form ;Flags: Precursor; |
| AC/ID | AC:P17405 ID:ASM_HUMAN |
| Feature Table for 565-th site |
VARIANT: /note="D -> Y (in NPDB; expresses protein level comparable to wild-type SMPD1 expressing cells; retains 6.8% residual enzyme activity)" /id="VAR_060929" CHAIN: /note="Sphingomyelin phosphodiesterase, processed form" /id="PRO_0000456684" CHAIN: /note="Sphingomyelin phosphodiesterase" /id="PRO_0000002323" |
| VARIANT for 565-th site |
D->Y LP/P " Niemann-Pick disease B (NPDB) " [MIM:607616] |
Percentages of Amino Acids in Homologous Proteins
 [show alignment]
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D:40% S:26% N:16% E:11% V:8% |
| Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
 5jg8 |
(coil) | e (exposed) | 42.0 |
| Predicted Bind Molecules |
| precipitant:6 |
| Templates for 3D complexes |
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precipitant [SO4 ] 5i81_A_1_W_1 5i81_A_2_W_2 5i85_A_1_Q_1 5i85_A_2_Q_2 5i85_A_3_Q_3 5i85_A_4_Q_4
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Summary for the 565-th Site(D)