Summary for the 291-st Site(R)
PID QueryLength FocusSite TITLE
2692367 631 291 R RecName: Full=Sphingomyelin phosphodiesterase ; EC=3.1.4.12 ; EC=3.1.4.3 ;AltName: Full=Acid sphingomyelinase ; Short=aSMase;Contains: RecName: Full=Sphingomyelin phosphodiesterase, processed form ;Flags: Precursor;
UniProt Information
AC/IDAC:P17405 ID:ASM_HUMAN
Feature Table for 291-th site VARIANT: /note="R -> H (in NPDB; uncertain significance; dbSNP:rs1803161)" ECO:0000269|PubMed:15877209" /id="VAR_060892"
HELIX:
CHAIN: /note="Sphingomyelin phosphodiesterase, processed form" /id="PRO_0000456684"
CHAIN: /note="Sphingomyelin phosphodiesterase" /id="PRO_0000002323"
VARIANT for 291-th site R->H US dbSNP:rs1803161 " Niemann-Pick disease B (NPDB) " [MIM:607616]
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
P:20% E:19% Q:12% T:10% R:8% G:7% S:6% N:5% I:5% A:4% Y:4%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5jg8 H (alpha-helix) e (exposed) 27.3
3D Complex Information
Predicted Bind Molecules
otherpoly:10
Templates for 3D complexes
otherpoly [2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 5i81_A_1_B_1 5i81_A_2_B_2 5i8r_A_1_D_1 5i8r_B_1_F_1 [beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 5i85_A_1_B_1 5i85_A_2_B_2 5i85_A_3_B_3 5i85_A_4_B_4 [2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 5jg8_A_1_E_1 [alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 5jg8_B_1_G_1


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