Summary for the 433-rd Site(C)
PID QueryLength FocusSite TITLE
2692367 631 433 C RecName: Full=Sphingomyelin phosphodiesterase ; EC=3.1.4.12 ; EC=3.1.4.3 ;AltName: Full=Acid sphingomyelinase ; Short=aSMase;Contains: RecName: Full=Sphingomyelin phosphodiesterase, processed form ;Flags: Precursor;
UniProt Information
AC/IDAC:P17405 ID:ASM_HUMAN
Feature Table for 433-th site VARIANT: /note="C -> R (in NPDB; dbSNP:rs779528546)" /id="VAR_060907"
DISULFID: ECO:0000269|PubMed:12631268, ECO:0000269|PubMed:27349982, ECO:0007744|PDB:5JG8"
CHAIN: /note="Sphingomyelin phosphodiesterase, processed form" /id="PRO_0000456684"
CHAIN: /note="Sphingomyelin phosphodiesterase" /id="PRO_0000002323"
VARIANT for 433-th site C->R LP/P dbSNP:rs7795285 " Niemann-Pick disease B (NPDB) " [MIM:607616]
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
C:33% F:11% L:10% N:8% I:7% M:6% A:5% S:5% T:5% W:5% Y:4%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5jg8 S (bend) b (buried) 0.0
3D Complex Information
Predicted Bind Molecules
compound:2 precipitant:1
Templates for 3D complexes
compound [RP5 ] 5ebe_B_1_T_1 [PC ] 5kas_A_1_L_1 precipitant [GOL ] 5kar_A_1_I_1


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