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| PID | QueryLength | FocusSite | TITLE |
| 2692367 | 631 | 525 Q | RecName: Full=Sphingomyelin phosphodiesterase ; EC=3.1.4.12 ; EC=3.1.4.3 ;AltName: Full=Acid sphingomyelinase ; Short=aSMase;Contains: RecName: Full=Sphingomyelin phosphodiesterase, processed form ;Flags: Precursor; |
| AC/ID | AC:P17405 ID:ASM_HUMAN |
| Feature Table for 525-th site |
VARIANT: /note="Q -> H (in NPDB; results in 64% of wild-type activity)" /id="VAR_068441" HELIX: CHAIN: /note="Sphingomyelin phosphodiesterase, processed form" /id="PRO_0000456684" CHAIN: /note="Sphingomyelin phosphodiesterase" /id="PRO_0000002323" |
| VARIANT for 525-th site |
Q->H LP/P " Niemann-Pick disease B (NPDB) " [MIM:607616] |
Percentages of Amino Acids in Homologous Proteins
 [show alignment]
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E:40% Q:24% D:11% I:10% K:7% S:7% |
| Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
 5jg8 |
H (alpha-helix) | e (exposed) | 62.2 |
| Predicted Bind Molecules |
| otherpoly:8 compound:3 |
| Templates for 3D complexes |
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otherpoly [2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 5i85_A_1_D_1 5i85_A_2_D_2 5i85_A_3_D_3 5i85_A_4_D_4 5i8r_C_1_I_1 5jg8_A_1_C_1 [beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 5i8r_B_1_H_1 [alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 5jg8_B_1_F_1
compound [NAG ] 5i81_A_1_J_1 5i81_A_2_J_2 5i8r_A_1_N_1
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Summary for the 525-th Site(Q)