Summary for the 373-rd Site(P)
PID QueryLength FocusSite TITLE
2692367 631 373 P RecName: Full=Sphingomyelin phosphodiesterase ; EC=3.1.4.12 ; EC=3.1.4.3 ;AltName: Full=Acid sphingomyelinase ; Short=aSMase;Contains: RecName: Full=Sphingomyelin phosphodiesterase, processed form ;Flags: Precursor;
UniProt Information
AC/IDAC:P17405 ID:ASM_HUMAN
Feature Table for 373-th site VARIANT: /note="P -> S (in NPDB; dbSNP:rs1342372980)" ECO:0000269|PubMed:22818240" /id="VAR_015289"
STRAND:
VAR_SEQ: /note="IGGFYALSPYPG -> YLSSVETQEGKR (in isoform 2)" /id="VSP_000331"
VAR_SEQ: /note="Missing (in isoform 3)" /id="VSP_000333"
CHAIN: /note="Sphingomyelin phosphodiesterase, processed form" /id="PRO_0000456684"
CHAIN: /note="Sphingomyelin phosphodiesterase" /id="PRO_0000002323"
VARIANT for 373-th site P->S LP/P dbSNP:rs1342372 " Niemann-Pick disease B (NPDB) " [MIM:607616]
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
V:44% P:27% I:14% S:6% A:4% N:3% T:3%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5jg8 S (bend) b (buried) 16.3
3D Complex Information
Predicted Bind Molecules
otherpoly:2 compound:5
Templates for 3D complexes
otherpoly [2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 5jg8_A_1_D_1 5jg8_B_1_I_1 compound [NAG ] 5i85_A_1_G_1 5i85_A_2_G_2 5i85_A_3_G_3 5i85_A_4_G_4 5i8r_C_1_CA_1


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