Summary for the 325-th Site(P)
PID QueryLength FocusSite TITLE
2692367 631 325 P RecName: Full=Sphingomyelin phosphodiesterase ; EC=3.1.4.12 ; EC=3.1.4.3 ;AltName: Full=Acid sphingomyelinase ; Short=aSMase;Contains: RecName: Full=Sphingomyelin phosphodiesterase, processed form ;Flags: Precursor;
UniProt Information
AC/IDAC:P17405 ID:ASM_HUMAN
Feature Table for 325-th site VARIANT: /note="P -> A (in NPDB; results in 1-4% of wild type activity; dbSNP:rs761308217)" ECO:0000269|PubMed:23430512, ECO:0000269|PubMed:26084044" /id="VAR_060896"
STRAND:
CHAIN: /note="Sphingomyelin phosphodiesterase, processed form" /id="PRO_0000456684"
CHAIN: /note="Sphingomyelin phosphodiesterase" /id="PRO_0000002323"
VARIANT for 325-th site P->A LP/P dbSNP:rs7613082 " Niemann-Pick disease B (NPDB) " [MIM:607616]
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
P:94% A:1% G:1% L:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5jg8 S (bend) b (buried) 1.6


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