Summary for the 161-st Site(N)
PID QueryLength FocusSite TITLE
2691701 207 161 N RecName: Full=Ras-related protein Rab-7a ; EC=3.6.5.2 ;
UniProt Information
AC/IDAC:P51149 ID:RAB7A_HUMAN
Feature Table for 161-th site VARIANT: /note="N -> T (in CMT2B; does not affect interaction with NTRK1; results in higher levels of NTRK1 and MAPK1/MAPK3 phosphorylation after NGF stimulation consistent with enhanced MAPK signaling; increases interaction with PRPH; dbSNP:rs121909080)" ECO:0000269|PubMed:21151572, ECO:0000269|PubMed:23179371" /id="VAR_037888"
CHAIN: /note="Ras-related protein Rab-7a" /id="PRO_0000121121"
VARIANT for 161-th site N->T LP/P dbSNP:rs1219090 " Charcot-Marie-Tooth disease, axonal, 2B (CMT2B) " [MIM:600882]
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
N:66% G:18% S:4% R:2% H:2% T:2% D:1% C:1% Q:1% E:1% L:1% K:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
1vg8 S (bend) e (exposed) 35.8
3D Complex Information
Predicted Bind Molecules
metal:3 precipitant:1
Templates for 3D complexes
metal [UNX ] 2ocb_A_1_G_1 [CL ] 4phh_B_1_J_1 4phh_D_1_O_1 precipitant [NO3 ] 4phf_A_1_D_1


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