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| PID | QueryLength | FocusSite | TITLE |
| 2691701 | 207 | 22 T | RecName: Full=Ras-related protein Rab-7a ; EC=3.6.5.2 ; |
| AC/ID | AC:P51149 ID:RAB7A_HUMAN |
| Feature Table for 22-th site |
MUTAGEN: /note="T->N: Abolishes localization on late endosomes, lysosomes and phagosomes and reduces phagosomal fusions. Abolishes association of RILP with the phagosomes. No loss of interaction with CLN5. No loss of interaction with PRPH. Reduced interaction with VPS13A. Inhibits SARS-CoV-2 infection." ECO:0000269|PubMed:22431521, ECO:0000269|PubMed:23179371, ECO:0000269|PubMed:30709847, ECO:0000269|PubMed:34159616" BINDING: /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" ECO:0000269|PubMed:20028791" HELIX: CHAIN: /note="Ras-related protein Rab-7a" /id="PRO_0000121121" |
Percentages of Amino Acids in Homologous Proteins
 [show alignment]
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T:53% S:44% G:1% L:1% K:1% |
| Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
 1vg8 |
H (alpha-helix) | e (exposed) | 26.6 |
| Predicted Bind Molecules |
| compound:10 metal:10 |
| Templates for 3D complexes |
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compound [GDP ] 1vg0_B_1_F_1 1vg1_A_1_C_1 1vg9_B_1_K_1 1vg9_D_1_O_1 1vg9_F_1_S_1 1vg9_H_1_W_1 [GNP ] 1vg8_A_1_F_1 1vg8_B_1_H_1 1vg8_C_1_J_1 1vg8_D_1_L_1
metal [MG ] 1vg0_B_1_E_1 1vg1_A_1_B_1 1vg8_A_1_E_1 1vg8_B_1_G_1 1vg8_C_1_I_1 1vg8_D_1_K_1 1vg9_B_1_I_1 1vg9_D_1_M_1 1vg9_F_1_Q_1 1vg9_H_1_U_1
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Summary for the 22-nd Site(T)