Summary for the 554-th Site(P)
PID QueryLength FocusSite TITLE
2690321 904 554 P RecName: Full=Toll-like receptor 3 ;AltName: CD_antigen=CD283;Flags: Precursor;
UniProt Information
AC/IDAC:O15455 ID:TLR3_HUMAN
Feature Table for 554-th site VARIANT: /note="P -> S (in IMD83; causes TLR3 deficiency and predisposition to herpes simplex encephalitis; inhibition of IFNL1 induction; dbSNP:rs121434431)" ECO:0000269|PubMed:32972995" /id="VAR_054887"
TOPO_DOM: /note="Lumenal"
CHAIN: /note="Toll-like receptor 3" /id="PRO_0000034715"
VARIANT for 554-th site P->S LP/P dbSNP:rs1214344 " Immunodeficiency 83, susceptibility to viral infections (IMD83) " [MIM:613002]
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
P:33% S:10% A:5% D:5% E:5% L:5% G:4% I:4% T:4% R:3% N:3% C:3% Q:3% K:3% V:3% F:2% Y:2% H:1% M:1% W:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
7c76 (coil) e (exposed) 25.6


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