Summary for the 554-th Site(P) |
PID | QueryLength | FocusSite | TITLE |
2690321 | 904 | 554 P | RecName: Full=Toll-like receptor 3 ;AltName: CD_antigen=CD283;Flags: Precursor; |
AC/ID | AC:O15455 ID:TLR3_HUMAN |
Feature Table for 554-th site |
VARIANT: /note="P -> S (in IMD83; causes TLR3 deficiency and predisposition to herpes simplex encephalitis; inhibition of IFNL1 induction; dbSNP:rs121434431)" ECO:0000269|PubMed:32972995" /id="VAR_054887" TOPO_DOM: /note="Lumenal" CHAIN: /note="Toll-like receptor 3" /id="PRO_0000034715" |
VARIANT for 554-th site |
P->S LP/P dbSNP:rs1214344 " Immunodeficiency 83, susceptibility to viral infections (IMD83) " [MIM:613002] |
Percentages of Amino Acids in Homologous Proteins [show alignment] |
P:33% S:10% A:5% D:5% E:5% L:5% G:4% I:4% T:4% R:3% N:3% C:3% Q:3% K:3% V:3% F:2% Y:2% H:1% M:1% W:1% |
Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
7c76 | (coil) | e (exposed) | 25.6 |
Predicted Bind Molecules |
otherpoly:1 compound:1 |
Templates for 3D complexes |
otherpoly [beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 3a79_B_1_H_1 compound [NAG ] 6ty5_A_1_M_1 |
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