Summary for the 759-th Site(Y)
PID QueryLength FocusSite TITLE
2690321 904 759 Y RecName: Full=Toll-like receptor 3 ;AltName: CD_antigen=CD283;Flags: Precursor;
UniProt Information
AC/IDAC:O15455 ID:TLR3_HUMAN
Feature Table for 759-th site MOD_RES: /note="Phosphotyrosine"
MUTAGEN: /note="Y->F: Reduced activation of NF-kappa-B in response to ds-RNA. Reduced induction of IL-8 in response to ds-RNA. Loss of interaction with WDFY1." ECO:0000269|PubMed:25736436"
DOMAIN: /note="TIR"
VARIANT: /note="Missing (inhibition of IFNL1 induction)" /id="VAR_084049"
TOPO_DOM: /note="Cytoplasmic"
CHAIN: /note="Toll-like receptor 3" /id="PRO_0000034715"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
F:76% Y:18% V:6%


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