Summary for the 574-th Site(T)
PID QueryLength FocusSite TITLE
2684896 1041 574 T RecName: Full=Toll-like receptor 8 ;AltName: CD_antigen=CD288;Flags: Precursor;
UniProt Information
AC/IDAC:Q9NR97 ID:TLR8_HUMAN
Feature Table for 574-th site MUTAGEN: /note="T->A: Abolishes responses to both ssRNA and chemical ligands."
MUTAGEN: /note="T->A: Strongly decreases activation of NF-kappa-B."
REPEAT: /note="LRR 16"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Toll-like receptor 8" /id="PRO_0000034735"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
T:16% L:11% P:11% I:9% V:6% C:5% E:5% K:5% F:5% S:5% A:4% G:4% R:3% D:3% N:2% Q:2% M:2% Y:2% H:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
4qbz (coil) e (exposed) 38.3
3D Complex Information
Predicted Bind Molecules
homo:58 compound:50 precipitant:2
Templates for 3D complexes
homo [99150:TLR8_HUMAN ] 3w3j_A_1_B_1 3w3j_B_1_A_1 3w3k_A_1_B_1 3w3k_B_1_A_1 3w3l_A_1_D_1 3w3l_B_1_C_1 3w3l_C_1_B_1 3w3l_D_1_A_1 3w3m_A_1_A_2 3w3m_A_2_A_1 3w3n_A_1_B_1 3w3n_B_1_A_1 4qbz_A_1_B_1 4qbz_B_1_A_1 4qc0_A_1_B_1 4qc0_B_1_A_1 4r07_A_1_B_1 4r07_B_1_A_1 4r07_C_1_D_1 4r07_D_1_C_1 4r08_A_1_B_1 4r08_B_1_A_1 4r08_C_1_D_1 4r08_D_1_C_1 4r09_B_1_A_1 4r09_C_1_D_1 4r09_D_1_C_1 4r0a_A_1_A_2 4r0a_A_2_A_1 4r6a_A_1_B_1 4r6a_B_1_A_1 5awa_A_1_A_2 5awa_A_2_A_1 5awb_A_1_A_2 5awb_A_2_A_1 5awc_A_1_B_1 5awc_B_1_A_1 5awc_C_1_D_1 5awc_D_1_C_1 5awd_A_1_A_2 5awd_A_2_A_1 5az5_A_1_B_1 5az5_B_1_A_1 5az5_C_1_D_1 5az5_D_1_C_1 5wyx_A_1_B_1 5wyx_B_1_A_1 5wyz_A_1_B_1 5wyz_B_1_A_1 5z14_A_1_B_1 5z14_B_1_A_1 5z15_A_1_B_1 5z15_B_1_A_1 6kya_A_1_B_1 6wml_A_1_B_1 6wml_B_1_A_1 6wml_C_1_D_1 [99299:TLR8_HUMAN ] 6wml_D_1_C_1 compound [C09 ] 3w3j_A_1_M_1 3w3j_B_1_V_1 [L07 ] 3w3k_A_1_I_1 3w3k_B_1_M_1 [RX8 ] 3w3l_A_1_KA_1 3w3l_B_1_AA_1 3w3l_C_1_EA_1 3w3l_D_1_JA_1 3w3m_A_1_E_2 3w3m_A_2_E_1 3w3n_A_1_O_1 3w3n_B_1_Q_1 [D80 ] 4qbz_A_1_O_1 4qbz_B_1_P_1 [XG1 ] 4qc0_A_1_J_1 4qc0_B_1_K_1 [URI ] 4r07_A_1_X_1 4r07_B_1_Q_1 4r07_C_1_KA_1 4r07_D_1_EA_1 4r08_A_1_X_1 4r08_B_1_Q_1 4r08_C_1_KA_1 4r08_D_1_FA_1 4r09_A_1_T_1 4r09_B_1_P_1 4r09_C_1_AA_1 4r09_D_1_Z_1 4r0a_A_1_E_2 4r0a_A_2_E_1 [HB2 ] 4r6a_A_1_M_1 4r6a_B_1_N_1 [M8D ] 5awa_A_1_E_2 5awa_A_2_E_1 [M0A ] 5awb_A_1_E_2 5awb_A_2_E_1 [M4D ] 5awc_A_1_T_1 5awc_B_1_U_1 5awc_C_1_Z_1 5awc_D_1_AA_1 [IDQ ] 5awd_A_1_E_2 5awd_A_2_E_1 [MBL ] 5az5_A_1_U_1 5az5_B_1_Q_1 5az5_C_1_EA_1 5az5_D_1_Z_1 [U57 ] 6wml_A_1_X_1 6wml_B_1_GA_1 6wml_C_1_NA_1 6wml_D_1_TA_1 precipitant [SO4 ] 3w3j_A_1_O_1 3w3j_B_1_AA_1


[Back to SiteTable]
[Back to Search Page]
[Back to Top Page]