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| PID | QueryLength | FocusSite | TITLE |
| 2684896 | 1041 | 432 P | RecName: Full=Toll-like receptor 8 ;AltName: CD_antigen=CD288;Flags: Precursor; |
| AC/ID | AC:Q9NR97 ID:TLR8_HUMAN |
| Feature Table for 432-th site |
VARIANT: /note="P -> L (in IMD98; gain-of-function variant resulting in increased NF-kappa-B activation measured in a reporter assay)" /id="VAR_087088" REPEAT: /note="LRR 12" TOPO_DOM: /note="Extracellular" CHAIN: /note="Toll-like receptor 8" /id="PRO_0000034735" |
| VARIANT for 432-th site |
P->L LP/P " Immunodeficiency 98 with autoinflammation, X-linked (IMD98) " [MIM:301078] |
Percentages of Amino Acids in Homologous Proteins
 [show alignment]
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G:23% P:15% S:9% A:8% E:8% V:6% T:5% D:4% C:4% R:2% N:2% Q:2% H:2% L:2% K:2% F:2% Y:2% I:1% W:1% |
| Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
 4qbz |
(coil) | e (exposed) | 20.9 |
| Predicted Bind Molecules |
| homo:14 |
| Templates for 3D complexes |
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homo [99150:TLR8_HUMAN
] 3w3g_B_1_A_1 5wyx_A_1_B_1 5wyx_B_1_A_1 5z14_A_1_B_1 5z14_B_1_A_1 6v9u_A_1_B_1 6v9u_B_1_A_1 6zjz_A_1_B_1 6zjz_B_1_A_1 7r54_A_1_B_1 7rc9_A_1_B_1 7rc9_B_1_A_1 7ytx_A_1_B_1 7ytx_B_1_A_1
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Summary for the 432-nd Site(P)