Summary for the 378-th Site(V)
PID QueryLength FocusSite TITLE
2684896 1041 378 V RecName: Full=Toll-like receptor 8 ;AltName: CD_antigen=CD288;Flags: Precursor;
UniProt Information
AC/IDAC:Q9NR97 ID:TLR8_HUMAN
Feature Table for 378-th site MUTAGEN: /note="V->A: Increases activation of NF-kappa-B."
REPEAT: /note="LRR 10"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Toll-like receptor 8" /id="PRO_0000034735"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
I:12% L:10% K:10% S:9% V:9% A:8% Q:8% F:5% E:4% T:4% R:3% N:3% D:3% G:3% H:3% M:2% P:2% Y:2% C:1% W:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
4qbz (coil) b (buried) 16.0
3D Complex Information
Predicted Bind Molecules
homo:26 compound:80
Templates for 3D complexes
homo [99150:TLR8_HUMAN ] 3w3g_A_1_B_1 3w3g_B_1_A_1 5wyx_A_1_B_1 5wyz_A_1_B_1 5wyz_B_1_A_1 5z14_A_1_B_1 5z14_B_1_A_1 5z15_A_1_B_1 5z15_B_1_A_1 6kya_A_1_B_1 6v9u_A_1_B_1 6v9u_B_1_A_1 6zjz_A_1_B_1 6zjz_B_1_A_1 7r52_A_1_B_1 7r52_B_1_A_1 7r53_A_1_B_1 7r53_B_1_A_1 7r54_A_1_B_1 7r54_B_1_A_1 7rc9_A_1_B_1 7rc9_B_1_A_1 7ytx_A_1_B_1 7ytx_B_1_A_1 8pfi_A_1_B_1 8pfi_B_1_A_1 compound [C09 ] 3w3j_A_1_V_1 3w3j_B_1_M_1 [L07 ] 3w3k_A_1_M_1 3w3k_B_1_I_1 [RX8 ] 3w3l_A_1_JA_1 3w3l_B_1_EA_1 3w3l_C_1_AA_1 3w3l_D_1_KA_1 3w3m_A_1_E_1 3w3m_A_2_E_2 3w3n_A_1_Q_1 3w3n_B_1_O_1 [D87 ] 3wn4_A_1_E_1 3wn4_A_2_E_2 [D80 ] 4qbz_A_1_P_1 4qbz_B_1_O_1 [XG1 ] 4qc0_A_1_K_1 4qc0_B_1_J_1 [URI ] 4r07_A_1_Q_1 4r07_B_1_X_1 4r07_C_1_EA_1 4r07_D_1_KA_1 4r08_A_1_Q_1 4r08_B_1_X_1 4r08_C_1_FA_1 4r08_D_1_KA_1 4r09_A_1_P_1 4r09_B_1_T_1 4r09_C_1_Z_1 4r09_D_1_AA_1 4r0a_A_1_E_1 4r0a_A_2_E_2 [HB2 ] 4r6a_A_1_N_1 4r6a_B_1_M_1 [M8D ] 5awa_A_1_E_1 5awa_A_2_E_2 [M0A ] 5awb_A_1_E_1 5awb_A_2_E_2 [M4D ] 5awc_A_1_U_1 5awc_B_1_T_1 5awc_C_1_AA_1 5awc_D_1_Z_1 [IDQ ] 5awd_A_1_E_1 5awd_A_2_E_2 [MBL ] 5az5_A_1_Q_1 5az5_B_1_U_1 5az5_C_1_Z_1 5az5_D_1_EA_1 [CU8 ] 5wyx_A_1_N_1 5wyx_B_1_M_1 [7VF ] 5wyz_A_1_M_1 5wyz_B_1_I_1 [7VC ] 5z14_A_1_I_1 5z14_B_1_L_1 [7VL ] 5z15_B_1_I_1 [DY3 ] 6kya_A_1_I_1 6kya_B_1_N_1 [O0W ] 6ty5_B_1_O_1 [QSM ] 6v9u_A_1_R_1 6v9u_B_1_AA_1 [U57 ] 6wml_A_1_GA_1 6wml_B_1_X_1 6wml_C_1_TA_1 6wml_D_1_NA_1 [QLH ] 6zjz_A_1_N_1 6zjz_B_1_S_1 [GD0 ] 7crf_A_1_U_1 7crf_B_1_I_1 [I6A ] 7r52_A_1_V_1 7r52_B_1_O_1 [I5N ] 7r53_A_1_P_1 7r53_B_1_O_1 [I5B ] 7r54_A_1_P_1 7r54_B_1_O_1 [RQY ] 7rc9_A_1_P_1 7rc9_B_1_X_1 [JRI ] 7ytx_A_1_I_1 7ytx_B_1_S_1 [YHG ] 8pfi_A_1_O_1 8pfi_B_1_P_1


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