Summary for the 67-th Site(D)

PID QueryLength FocusSite TITLE
2624989 215 67 D RecName: Full=High mobility group protein B1;AltName: Full=High mobility group protein 1; Short=HMG-1;
UniProt Information
AC/IDAC:P09429 ID:HMGB1_HUMAN
Feature Table for 67-th site MUTAGEN: /note="D->A: Abolishes cleavage by CASP1 and impairs ability to antagonize apoptosis-induced immune tolerance."
SITE: /note="Cleavage; by CASP1"
HELIX:
DNA_BIND: /note="HMG box 1"
REGION: /note="Sufficient for interaction with HAVCR2"
CHAIN: /note="High mobility group protein B1" /id="PRO_0000048526"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
D:50% A:12% E:9% L:9% K:8% N:6% R:3% M:2% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
2yrq H (alpha-helix) b (buried) 4.9
3D Complex Information
Predicted Bind Molecules
precipitant:1
Templates for 3D complexes
precipitant [EDO ] 7lbw_B_1_L_1


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