Summary for the 175-th Site(E)
PID QueryLength FocusSite TITLE
2622207 358 175 E RecName: Full=HLA class I histocompatibility antigen, alpha chain E;AltName: Full=MHC class I antigen E;Contains: RecName: Full=Soluble HLA class I histocompatibility antigen, alpha chain E; Short=sHLA-E ;Flags: Precursor;
UniProt Information
AC/IDAC:P13747 ID:HLAE_HUMAN
Feature Table for 175-th site MUTAGEN: /note="E->A: Has no impact on the affinity for KLRD1- KLRC1."
HELIX:
REGION: /note="Alpha-2"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="HLA class I histocompatibility antigen, alpha chain E" /id="PRO_0000018882"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
E:39% D:13% Q:10% L:8% N:7% T:7% K:4% V:4% R:3% A:1% H:1% I:1% M:1% P:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
7p4b H (alpha-helix) e (exposed) 57.3
3D Complex Information
Predicted Bind Molecules
hetero:257 compound:1 metal:19 precipitant:21
Templates for 3D complexes
hetero [47918 ] 1lp9_A_1_D_1 1lp9_F_1_I_1 2j8u_A_1_D_1 2j8u_F_1_I_1 2jcc_A_1_D_1 2jcc_F_1_I_1 2uwe_A_1_D_1 2uwe_F_1_I_1 [49240:TCA_HUMAN ] 1mi5_A_1_D_1 3kpr_A_1_D_1 3kpr_F_1_I_1 3kps_A_1_D_1 [48794 ] 1oga_A_1_D_1 2vlj_A_1_D_1 2vlk_A_1_D_1 2vlr_A_1_D_1 2vlr_F_1_I_1 5euo_A_1_E_1 5hho_A_1_C_1 [47838:TCA_HUMAN ] 1qrn_A_1_D_1 3d39_A_1_D_1 3d3v_A_1_D_1 3h9s_A_1_D_1 4ftv_A_1_D_1 [60212 ] 1qrn_A_1_E_1 1qse_A_1_E_1 3d3v_A_1_E_1 3pwp_A_1_E_1 3qfj_A_1_E_1 6rpb_A_1_E_1 6rpb_F_1_J_1 6rpb_K_1_O_1 6rpb_P_1_T_1 7r80_A_1_E_1 [49750 ] 2ak4_A_1_D_1 2ak4_F_1_I_1 2ak4_K_1_N_1 2ak4_P_1_S_1 3kxf_A_1_D_1 3kxf_C_1_G_1 3kxf_I_1_K_1 3kxf_P_1_R_1 4jrx_A_1_D_1 [59920 ] 2ak4_A_1_E_1 2ak4_P_1_T_1 3kxf_I_1_L_1 5xot_A_1_E_1 6bj8_A_1_D_1 [47513 ] 2bnq_A_1_D_1 2bnr_A_1_D_1 2f53_A_1_D_1 2f54_A_1_D_1 2f54_F_1_I_1 2p5e_A_1_D_1 2p5w_A_1_D_1 [48635:TCA_HUMAN ] 2esv_A_1_D_1 7ndt_A_1_D_1 7ndt_F_1_I_1 [46685 ] 2nx5_A_1_D_1 2nx5_K_1_N_1 2nx5_P_1_S_1 [60579 ] 2nx5_A_1_E_1 [48786 ] 2ypl_A_1_D_1 [59881 ] 2ypl_A_1_E_1 [30396:NKG2A_HUMAN ] 3cdg_A_1_D_1 3cdg_E_1_H_1 3cii_A_1_H_1 [48659 ] 3dxa_A_1_D_1 3dxa_F_1_I_1 3dxa_K_1_N_1 [46903 ] 3hg1_A_1_D_1 3vxu_A_1_D_1 3vxu_F_1_I_1 3w0w_A_1_D_1 4l3e_A_1_D_1 4qok_A_1_D_1 6amu_A_1_D_1 6eqa_A_1_D_1 7pbc_A_1_C_1 7pdw_I_1_A_1 7pdw_J_1_E_1 7q99_A_1_D_1 7q9a_A_1_D_1 7q9b_A_1_D_1 7q9b_F_1_I_1 7qpj_A_1_D_1 [48012 ] 3o4l_A_1_D_1 [47839 ] 3qdm_A_1_D_1 3qeq_A_1_D_1 [49586 ] 3sjv_A_1_D_1 3sjv_F_1_I_1 3sjv_K_1_N_1 3sjv_P_1_S_1 [51313 ] 3vxm_A_1_D_1 [49980 ] 3vxs_A_1_C_1 [50188 ] 4eup_A_1_G_1 4eup_D_1_H_1 [49853 ] 4g8g_A_1_D_1 [48167 ] 4jfd_A_1_D_1 4jfe_A_1_D_1 4jff_A_1_D_1 6eqb_A_1_D_1 6tmo_A_1_D_1 [48047 ] 4mji_A_1_D_1 4mji_F_1_I_1 [48925:H2RG00_PANTR :K7N5M9_HUMAN ] 4mnq_A_1_D_1 5men_A_1_D_1 [50234 ] 4qrp_A_1_D_1 [50151 ] 4qrr_A_1_C_1 [48458:A0A0B4J279_HUMAN :TCA_HUMAN ] 5brz_A_1_D_1 5bs0_A_1_D_1 [47323 ] 5c08_F_1_I_1 5hyj_F_1_I_1 6vqo_A_1_C_1 [48863 ] 5d2l_A_1_C_1 5d2l_K_1_M_1 5d2l_P_1_R_1 [49522 ] 5d2n_C_1_A_1 5d2n_G_1_E_1 [50568:K7N5M3_HUMAN ] 5e6i_H_1_F_1 5e6i_M_1_K_1 [27619:A0A075B6T6_HUMAN ] 5e9d_A_1_D_1 5e9d_F_1_I_1 [49783 ] 5eu6_A_1_D_1 8cx4_A_1_D_1 [48943 ] 5isz_A_1_D_1 [59681 ] 5isz_A_1_E_1 5jhd_A_1_E_1 5jhd_F_1_J_1 [47311 ] 5jzi_A_1_G_1 5jzi_D_1_I_1 5yxn_C_1_A_1 5yxu_E_1_C_1 5yxu_G_1_A_2 [49034 ] 5nme_A_1_D_1 5nme_F_1_I_1 5nmf_A_1_D_1 5nmf_F_1_I_1 5nmg_A_1_D_1 5nmg_F_1_I_1 [50195 ] 5tez_B_1_D_1 [50408 ] 5w1v_A_1_D_1 5w1v_F_1_I_1 5w1v_K_1_N_1 5w1w_A_1_D_1 5w1w_F_1_I_1 5w1w_P_1_S_1 [60097 ] 5wkf_A_1_E_1 5wkf_F_1_J_1 5wkh_F_1_J_1 [51156:Q6IRV4_HUMAN ] 6bj2_C_1_A_1 [49794:Q6IRV4_HUMAN ] 6bj8_A_1_C_1 [48939:K7N5M3_HUMAN ] 6d78_A_1_D_1 [63704 ] 6d7g_A_2_C_1 [47694 ] 6mtm_A_1_D_1 [50545 ] 6p64_A_1_E_3 [47915:TVA22_HUMAN :K7N5M3_HUMAN ] 6r2l_A_1_D_1 [50191 ] 6rp9_F_1_I_1 6vm9_A_1_D_2 6vma_A_1_C_2 6vmc_C_1_A_2 [51631 ] 6rpa_A_1_D_1 [50190 ] 6rpb_A_1_D_1 6rpb_F_1_I_1 6rpb_K_1_N_1 6rpb_P_1_S_1 [50713 ] 6rsy_A_1_D_1 6rsy_F_1_I_1 [60272 ] 6rsy_A_1_E_1 6rsy_F_1_J_1 [60146 ] 6ulr_A_1_E_2 [49354 ] 6uon_E_1_C_1 6uon_H_1_A_1 [50571 ] 6vm7_C_1_A_2 [49576 ] 6vmx_A_1_D_1 6vmx_F_1_I_1 [49905 ] 6vrm_A_1_C_1 [51609 ] 6vrn_A_1_C_1 [48791 ] 6zkw_A_1_D_1 6zkx_A_1_D_1 6zky_A_1_D_1 6zkz_A_1_D_1 [60518 ] 7dzm_A_1_D_1 7dzn_A_1_D_1 [49793 ] 7dzm_A_1_E_1 7dzn_A_1_E_1 [50155 ] 7l1d_A_2_D_1 [49792 ] 7n1e_A_1_D_1 [48807 ] 7n1f_C_1_A_1 7rtr_A_1_D_1 [51104 ] 7n2o_B_1_D_1 [49387 ] 7n2p_A_1_D_1 7n2q_C_1_A_1 [50789 ] 7n2s_B_1_D_1 [49355 ] 7n6e_A_1_H_1 7n6e_D_1_G_1 [48790:TVA4_HUMAN :A0A075B6U7_HUMAN :TRAR1_HUMAN ] 7ndq_A_1_D_1 7ndu_A_1_D_1 [60172:TVB14_HUMAN :TJB23_HUMAN :TRBC2_HUMAN ] 7ndt_A_1_J_1 [47435 ] 7nme_A_1_D_1 7nmf_A_1_D_1 7nmg_A_1_D_1 [49570 ] 7ow5_A_1_D_1 [49599 ] 7ow6_A_1_D_1 [49597 ] 7pbe_A_1_D_1 [62367 ] 7phr_F_1_A_1 [55880 ] 7re7_E_1_C_1 [50257 ] 7rm4_A_1_E_1 7rm4_F_1_J_1 7rm4_K_1_O_1 7rm4_P_1_T_1 [50433 ] 7rrg_A_1_C_2 [52255 ] 7tr4_A_1_C_1 [50049 ] 8en8_A_1_D_1 8en8_F_1_I_1 8enh_A_1_D_1 8enh_F_1_I_1 8enh_P_1_S_1 8eo8_A_1_D_1 8eo8_F_1_I_1 8eo8_P_1_S_1 [66489 ] 8es9_I_1_A_1 [50502 ] 8f5a_A_1_C_1 [55685 ] 8fjb_A_1_D_1 [50470 ] 8gom_A_1_D_1 8gon_A_1_D_1 [50873 ] 8gvb_C_1_A_1 [50110 ] 8gvg_C_1_A_1 8gvi_C_1_A_1 [48734 ] 8i5c_A_1_D_1 8i5c_EA_1_HA_1 8i5c_F_1_I_1 8i5c_JA_1_MA_1 8i5c_K_1_N_1 8i5c_OA_1_RA_1 8i5c_TA_1_WA_1 8i5c_Z_1_CA_1 [59462 ] 8i5c_A_1_E_1 8i5c_EA_1_IA_1 8i5c_F_1_J_1 8i5c_JA_1_NA_1 8i5c_K_1_O_1 8i5c_OA_1_SA_1 8i5c_P_1_T_1 8i5c_TA_1_XA_1 8i5c_U_1_Y_1 8i5c_Z_1_DA_1 [47796 ] 8i5d_C_1_A_1 [48486 ] 8qfy_A_1_D_1 8qfy_F_1_I_1 [29398:Q9WU32_MOUSE ] 8umo_A_1_D_1 [48503 ] 8wte_C_1_A_1 8wte_H_1_F_1 8wul_I_1_A_1 8wul_L_1_C_1 8wul_O_1_E_1 8wul_R_1_G_1 compound [TAM ] 6tmo_A_1_O_1 metal [MG ] 3fqn_A_1_H_1 3fqx_A_1_H_1 6opd_A_1_I_1 [CD ] 3fqt_A_1_H_1 3fqu_A_1_H_1 3fqu_A_1_K_1 3fqw_A_1_H_1 4nnx_A_1_D_1 4nny_A_1_D_1 6ei2_A_1_H_1 7kgo_A_1_H_1 7kgp_A_1_E_1 7u1r_A_1_D_1 7um2_A_1_E_1 8fu4_A_1_E_1 [CO ] 6q3k_A_1_I_1 [3NI ] 7kgo_A_1_E_1 [ZN ] 7sis_A_1_F_1 [NA ] 7u1r_A_1_F_1 precipitant [GOL ] 1tvb_D_1_Z_1 1tvh_D_1_AA_1 1x7q_A_1_J_1 2av7_D_1_W_1 2git_D_1_O_1 3kww_A_1_K_1 4jfo_A_1_G_1 6bj8_A_1_V_1 6o53_A_1_E_1 6vm7_C_1_F_1 [SO4 ] 4jfd_A_1_I_1 5c0c_A_1_YA_1 5nmf_A_1_O_1 5nmf_F_1_GA_1 [EDO ] 4u1m_A_1_L_1 4z78_A_1_L_1 5eu5_A_1_G_1 5nme_A_1_K_1 5nmg_A_1_L_1 5w67_A_1_F_1 7wt4_A_1_I_1


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