Summary for the 187-th Site(E)
PID QueryLength FocusSite TITLE
2622207 358 187 E RecName: Full=HLA class I histocompatibility antigen, alpha chain E;AltName: Full=MHC class I antigen E;Contains: RecName: Full=Soluble HLA class I histocompatibility antigen, alpha chain E; Short=sHLA-E ;Flags: Precursor;
UniProt Information
AC/IDAC:P13747 ID:HLAE_HUMAN
Feature Table for 187-th site MUTAGEN: /note="E->A: Reduces the affinity for KLRD1-KLRC1."
HELIX:
REGION: /note="Alpha-2"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="HLA class I histocompatibility antigen, alpha chain E" /id="PRO_0000018882"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
E:25% R:20% Q:15% A:9% S:6% G:5% H:3% L:3% Y:3% D:2% T:2% N:1% I:1% K:1% F:1% P:1% V:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
7p4b H (alpha-helix) e (exposed) 48.7
3D Complex Information
Predicted Bind Molecules
hetero:119 compound:3 metal:1 precipitant:85
Templates for 3D complexes
hetero [27619 ] 1ao7_A_1_D_1 1ao7_A_4_D_4 [47918 ] 1lp9_A_1_D_1 1lp9_F_1_I_1 2j8u_A_1_D_1 2j8u_F_1_I_1 2jcc_A_1_D_1 2jcc_F_1_I_1 2uwe_A_1_D_1 2uwe_F_1_I_1 [47838:TCA_HUMAN ] 1qrn_A_1_D_1 1qse_A_1_D_1 1qsf_A_1_D_1 2gj6_A_1_D_1 3d39_A_1_D_1 3d3v_A_1_D_1 3h9s_A_1_D_1 3pwp_A_1_D_1 3qfj_A_1_D_1 4ftv_A_1_D_1 [22561:B2MG_HUMAN ] 1ydp_A_2_B_1 [49750 ] 2ak4_P_1_S_1 3kxf_A_1_D_1 3kxf_C_1_G_1 3kxf_I_1_K_1 3kxf_P_1_R_1 4jrx_A_1_D_1 [46685 ] 2nx5_A_1_D_1 2nx5_F_1_I_1 2nx5_K_1_N_1 2nx5_P_1_S_1 [49328 ] 3ffc_A_1_D_1 3ffc_F_1_I_1 [54497 ] 3gjf_A_1_I_1 3gjf_D_1_J_1 [46903 ] 3hg1_A_1_D_1 3qdg_A_1_D_1 3qdj_A_1_D_1 3vxu_A_1_D_1 3vxu_F_1_I_1 3w0w_A_1_D_1 4qok_A_1_D_1 6am5_A_1_D_1 6dkp_A_1_D_1 6eqa_A_1_D_1 7q9a_A_1_D_1 7q9b_A_1_D_1 7q9b_F_1_I_1 8dnt_D_1_A_1 8dnt_I_1_F_1 8dnt_N_1_K_1 [48012 ] 3o4l_A_1_D_1 [2889:Q9YYU3_9HIV1 ] 3vxm_A_1_C_1 [51313 ] 3vxm_A_1_D_1 [2565:Q9WPU2_9HIV1 ] 3vxs_A_1_E_1 [49233 ] 4jry_A_1_D_1 [48047 ] 4mji_A_1_D_1 4mji_F_1_I_1 [48925:H2RG00_PANTR :K7N5M9_HUMAN ] 4mnq_A_1_D_1 5men_A_1_D_1 [55665 ] 4wuu_A_1_E_1 [48458:A0A0B4J279_HUMAN :TCA_HUMAN ] 5brz_A_1_D_1 5bs0_A_1_D_1 [48863 ] 5d2l_P_1_R_1 [48943 ] 5isz_A_1_D_1 [52029 ] 5jhd_A_1_D_1 5jhd_F_1_I_1 [49034 ] 5nme_A_1_D_1 5nme_F_1_I_1 5nmf_A_1_D_1 5nmf_F_1_I_1 5nmg_F_1_I_1 [50188:A0A075B6T6_HUMAN :A0A075B6X0_HUMAN :A0A1B0GUM0_HUMAN ] 5nqk_A_1_D_1 [47311 ] 5yxu_E_1_C_1 [50436:A0A0B4J268_HUMAN ] 6avf_E_1_B_1 [49412:A0A0B4J268_HUMAN ] 6avg_D_1_B_1 6avg_H_1_F_1 [48939:K7N5M3_HUMAN ] 6d78_A_1_D_1 [48167 ] 6eqb_A_1_D_1 [3945 ] 6lf8_A_1_C_1 [47915:TVA22_HUMAN :K7N5M3_HUMAN ] 6r2l_A_1_D_1 [50713 ] 6rsy_A_1_D_1 [50673 ] 6tro_A_1_D_1 [50197 ] 6uln_A_1_D_2 6ulr_A_1_D_2 [50191 ] 6vmc_C_1_A_2 [49576 ] 6vmx_F_1_I_1 [55661 ] 7bbg_A_1_D_1 [51261 ] 7bh8_A_1_F_1 7bh8_C_1_H_1 [48613 ] 7byd_A_1_D_1 7byd_F_1_I_1 [48807 ] 7n1f_C_1_A_1 7rtr_A_1_D_1 [51104 ] 7n2o_B_1_D_1 [49387 ] 7n2q_H_1_F_1 [47435 ] 7nmg_A_1_D_1 [62367 ] 7phr_F_1_A_1 [55181 ] 8eb2_A_1_L_1 8eb2_D_1_J_1 8eb2_G_1_N_1 [88307 ] 8ek5_A_1_D_1 [50049 ] 8enh_F_1_I_1 8enh_P_1_S_1 8eo8_F_1_I_1 8eo8_P_1_S_1 [67109 ] 8es8_I_1_G_1 [59419 ] 8fja_C_1_B_1 [50873 ] 8gvb_C_1_A_1 [50110 ] 8gvg_C_1_A_1 8gvi_C_1_A_1 [47796 ] 8i5d_C_1_A_1 [48486 ] 8qfy_A_1_D_1 8qfy_F_1_I_1 [48503 ] 8wte_C_1_A_1 8wte_H_1_F_1 8wul_I_1_A_1 8wul_L_1_C_1 8wul_R_1_G_1 compound [XPE ] 3rwg_A_1_D_1 [15P ] 4z77_D_1_X_1 [PE8 ] 6z9v_D_1_Z_1 metal [NA ] 7rtr_A_1_G_1 precipitant [1PG ] 1i4f_A_1_D_1 [GOL ] 1uxs_A_1_E_1 2a83_A_1_F_1 2av7_A_1_J_1 2gtz_A_1_J_1 2p5e_A_1_J_1 3bxn_A_1_D_1 3d18_A_1_E_1 3fqt_A_1_K_1 3fqu_A_1_F_1 3o3b_A_1_K_1 4wj5_D_1_O_1 5fa3_A_1_E_1 5ib2_A_1_E_1 5isz_A_1_F_1 5t6y_A_1_E_1 6bj8_A_1_J_1 6o51_A_1_G_1 6o53_A_1_F_1 6vb7_A_1_G_1 6vmc_C_1_F_1 6y26_A_1_D_1 6y27_A_1_F_1 6y29_A_1_D_1 6y2a_A_1_F_1 6y2b_A_1_G_1 7n2p_A_1_I_1 7pbc_A_1_H_1 7pdw_I_1_M_1 7qpj_A_1_F_1 7r7y_A_1_F_1 [SO4 ] 2p5w_A_1_G_1 2pye_A_1_F_1 2pye_A_1_G_1 4z76_D_1_V_1 4z78_A_1_R_1 5c0i_A_1_K_1 5eu6_A_1_M_1 5nmf_A_1_P_1 5nmg_A_1_P_1 6ggm_A_1_J_1 6gh1_D_1_P_1 6gh4_C_1_Q_1 6ss9_A_1_J_1 6z9v_A_1_J_1 6z9v_D_1_X_1 7p49_C_1_AA_1 7p49_E_1_LA_1 7p49_G_1_SA_1 7p4b_C_1_U_1 [EDO ] 4gks_D_1_R_1 4u1h_A_1_H_1 4u1m_A_1_G_1 4u1m_A_1_H_1 4u1n_A_1_J_1 4u1s_A_1_J_1 5c0e_A_1_J_1 5c0g_A_1_J_1 5nmf_F_1_CA_1 5nmh_A_1_H_1 6iwg_A_1_O_1 6lt6_A_1_E_1 6r2l_A_1_G_1 6r2l_A_1_H_1 6tdq_A_1_F_1 6tdr_A_1_G_1 6tds_C_1_T_1 6tmo_A_1_I_1 6uzs_A_1_I_1 6vmx_A_1_L_1 8rbu_A_1_I_1 8ref_A_1_H_1 [PEG ] 4u6x_A_1_F_1 6uj8_A_1_I_1 6uj9_A_1_G_1 6vmx_F_1_O_1 [IMD ] 5euo_C_1_K_1 6o9b_A_1_G_1 [ACT ] 6opd_A_1_D_1 6uzm_A_1_F_1 6vb4_A_1_D_1 6viu_A_1_D_1 [FLC ] 6vm8_A_1_F_2 [P6G ] 7lg0_A_1_D_1 [PG4 ] 7re7_E_1_Q_1


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