Summary for the 278-th Site(V) |
PID | QueryLength | FocusSite | TITLE |
13847 | 468 | 278 V | RecName: Full=Interleukin-6 receptor subunit alpha ; Short=IL-6 receptor subunit alpha; Short=IL-6R subunit alpha; Short=IL-6R-alpha; Short=IL-6RA;AltName: Full=IL-6R 1;AltName: Full=Membrane glycoprotein 80; Short=gp80;AltName: CD_antigen=CD126;Contains: RecName: Full=Soluble interleukin-6 receptor subunit alpha ; Short=sIL6R ;Flags: Precursor; |
AC/ID | AC:P08887 ID:IL6RA_HUMAN |
Feature Table for 278-th site |
MUTAGEN: /note="V->N: 50% Decrease of ligand-binding and 50% increase in IL6 signaling." STRAND: DOMAIN: /note="Fibronectin type-III 2" CHAIN: /note="Soluble interleukin-6 receptor subunit alpha" /id="PRO_0000450730" TOPO_DOM: /note="Extracellular" CHAIN: /note="Interleukin-6 receptor subunit alpha" /id="PRO_0000010895" |
Percentages of Amino Acids in Homologous Proteins [show alignment] |
V:25% K:20% T:17% D:11% R:8% I:5% C:4% F:4% N:3% L:2% |
Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
1n26 | E (beta-strand) | e (exposed) | 27.3 |
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