type start end name pdb_id identity asym_id_homo oper_homo auth_asym_id_homo mol_id_homo asym_id_con oper_con auth_asym_id_con mol_id_con sites description_homo description_con length 1 918 id 1 918 IL6RB_HUMAN title 1 918 RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor; seq 1 918 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEGMPKSYLPQTVRQGGYMPQ uniprot 1 22 SIGNAL uniprot 23 918 CHAIN /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899" uniprot 23 619 TOPO_DOM /note="Extracellular" uniprot 620 641 TRANSMEM /note="Helical" uniprot 642 918 TOPO_DOM /note="Cytoplasmic" uniprot 26 120 DOMAIN /note="Ig-like C2-type" uniprot 125 216 DOMAIN /note="Fibronectin type-III 1" uniprot 224 324 DOMAIN /note="Fibronectin type-III 2" uniprot 329 424 DOMAIN /note="Fibronectin type-III 3" uniprot 426 517 DOMAIN /note="Fibronectin type-III 4" uniprot 518 613 DOMAIN /note="Fibronectin type-III 5" uniprot 660 681 REGION /note="Disordered" uniprot 722 758 REGION /note="Disordered" uniprot 724 758 COMPBIAS /note="Polar residues" disorder 1 27 predicted_by_DISOPRED disorder 666 797 predicted_by_DISOPRED disorder 808 811 predicted_by_DISOPRED disorder 815 815 predicted_by_DISOPRED disorder 817 818 predicted_by_DISOPRED disorder 820 820 predicted_by_DISOPRED disorder 875 906 predicted_by_DISOPRED disorder 908 913 predicted_by_DISOPRED disorder 915 918 predicted_by_DISOPRED pdb_monomer 24 612 monomer 8d82 100.0 F E IL6RB_HUMAN 24-612 pdb_complex 24 324 hetero 1i1r 100.0 A 1 A IL6RB_HUMAN B 1 B Q98823_HHV8 164:166:187-192:248:251:252 INTERLEUKIN-6 RECEPTOR BETA CHAIN VIRAL IL-6[167 aa] pdb_complex 24 324 hetero 1i1r 100.0 A 1 A IL6RB_HUMAN B 2 B Q98823_HHV8 24-28:34:35:71:100:102:104:105:112-117 INTERLEUKIN-6 RECEPTOR BETA CHAIN VIRAL IL-6[167 aa] pdb_complex 24 321 hetero 1p9m 100.0 A 1 A IL6RB_HUMAN B 1 B IL6_HUMAN 139:140:164:167:187:190-193:215:251:252 Interleukin-6 receptor beta chain Interleukin-6[163 aa] pdb_complex 24 321 hetero 1p9m 100.0 A 1 A IL6RB_HUMAN B 2 B IL6_HUMAN 24-28:51:53:54:58:105:112-117 Interleukin-6 receptor beta chain Interleukin-6[163 aa] pdb_complex 24 321 hetero 1p9m 100.0 A 1 A IL6RB_HUMAN C 1 C IL6RA_HUMAN 233:234:241:254:276:279:281:283-285:287 Interleukin-6 receptor beta chain Interleukin-6 receptor alpha chain[201 aa] pdb_complex 24 321 hetero 1p9m 100.0 A 1 A IL6RB_HUMAN C 2 C IL6RA_HUMAN 57:59:111:113 Interleukin-6 receptor beta chain Interleukin-6 receptor alpha chain[201 aa] pdb_complex 123 323 hetero 1pvh 100.0 A 1 A IL6RB_HUMAN B 1 B LIF_HUMAN 163-168:187:191-193:195:213:215 Interleukin-6 receptor beta chain Leukemia inhibitory factor[169 aa] pdb_complex 124 515 hetero 8d6a 100.0 B 1 A IL6RB_HUMAN A 1 D LIF_HUMAN 163:165:167:168:190-193:195:215 Interleukin-6 receptor subunit beta Leukemia inhibitory factor[169 aa] pdb_complex 24 321 hetero 7u7n 100.0 B 1 B IL6RB_HUMAN C 1 C IL27B_HUMAN 57:108:109:113 Interleukin-6 receptor subunit beta Interleukin-27 subunit beta[200 aa] pdb_complex 24 321 hetero 7u7n 100.0 B 1 B IL6RB_HUMAN D 1 D IL27A_HUMAN 34:35:70:100:102:111-114:116:117:119 Interleukin-6 receptor subunit beta Interleukin-27 subunit alpha[191 aa] pdb_complex 124 515 hetero 8d74 100.0 A 1 A IL6RB_HUMAN B 1 D CNTF_HUMAN 164:166:167:169:189-193:215:251:252 Interleukin-6 receptor subunit beta Ciliary neurotrophic factor[174 aa] pdb_complex 124 515 hetero 8d74 100.0 A 1 A IL6RB_HUMAN C 1 C CNTFR_HUMAN 233:235:239:241:276:281:283-285:287:288 Interleukin-6 receptor subunit beta Ciliary neurotrophic factor receptor subunit alpha.. pdb_complex 124 515 hetero 8d7r 100.0 D 1 A IL6RB_HUMAN A 1 D CLCF1_HUMAN 187:188:190:191:215 Interleukin-6 receptor subunit beta Cardiotrophin-like cytokine factor 1[178 aa] pdb_complex 24 612 hetero 8d82 100.0 C 1 A IL6RB_HUMAN A 1 C IL6RA_HUMAN 235:236:239:241:254:275:276:281:283:285:287 Interleukin-6 receptor subunit beta Soluble interleukin-6 receptor subunit alpha[296 a.. pdb_complex 24 612 hetero 8d82 100.0 C 1 A IL6RB_HUMAN D 1 G IL6RA_HUMAN 57:108:110:111 Interleukin-6 receptor subunit beta Soluble interleukin-6 receptor subunit alpha[296 a.. pdb_complex 26 322 hetero 8dps 100.0 A 1 A IL6RB_HUMAN B 1 B IL11_HUMAN 164:165:167:169:187-192 Interleukin-6 receptor subunit beta Interleukin-11[165 aa] pdb_complex 26 322 hetero 8dps 100.0 A 1 A IL6RB_HUMAN E 1 E IL11_HUMAN 27:34:68:71:100:102:104:112-117 Interleukin-6 receptor subunit beta Interleukin-11[165 aa] pdb_complex 26 322 hetero 8dps 100.0 A 1 A IL6RB_HUMAN C 1 C I11RA_HUMAN 235:239:275:276:280-285:287 Interleukin-6 receptor subunit beta Interleukin-11 receptor subunit alpha[200 aa] pdb_complex 26 322 hetero 8dps 100.0 A 1 A IL6RB_HUMAN F 1 F I11RA_HUMAN 110:111 Interleukin-6 receptor subunit beta Interleukin-11 receptor subunit alpha[200 aa] pdb_complex 24 421 hetero 8dpt 100.0 A 1 A IL6RB_HUMAN C 1 C I11RA_HUMAN 233:235:241:275:276:280-285:287 Interleukin-6 receptor subunit beta Interleukin-11 receptor subunit alpha[294 aa] pdb_complex 24 421 hetero 8dpt 100.0 A 1 A IL6RB_HUMAN F 1 F I11RA_HUMAN 24:108:110:111 Interleukin-6 receptor subunit beta Interleukin-11 receptor subunit alpha[294 aa] pdb_complex 24 321 compound 7u7n 100.0 B 1 B IL6RB_HUMAN K 1 B NAG 130:131 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 24 321 compound 7u7n 100.0 B 1 B IL6RB_HUMAN L 1 B NAG 155:157:173:201 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 124 515 compound 8d6a 100.0 B 1 A IL6RB_HUMAN J 1 A NAG 341:344:390 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 124 515 compound 8d6a 100.0 B 1 A IL6RB_HUMAN L 1 A NAG 364:383 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 124 515 compound 8d6a 100.0 B 1 A IL6RB_HUMAN M 1 A NAG 379 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 24 612 compound 8d82 100.0 C 1 A IL6RB_HUMAN T 1 A NAG 227 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 24 612 compound 8d82 100.0 C 1 A IL6RB_HUMAN Y 1 A NAG 562-564 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 26 322 compound 8dps 100.0 A 1 A IL6RB_HUMAN K 1 A NAG 43:92 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 123 323 metal 1pvh 100.0 A 1 A IL6RB_HUMAN E 1 A IOD 310 Interleukin-6 receptor beta chain IODIDE ION[1 atoms] pdb_complex 323 612 metal 3l5i 100.0 A 1 A IL6RB_HUMAN O 1 A CL 531-534 Interleukin-6 receptor subunit beta CHLORIDE ION[1 atoms] pdb_complex 323 612 metal 3l5i 100.0 A 1 A IL6RB_HUMAN Q 1 A CL 510:511 Interleukin-6 receptor subunit beta CHLORIDE ION[1 atoms] pdb_complex 323 612 metal 3l5i 100.0 A 1 A IL6RB_HUMAN T 1 A CL 331:471:472:483 Interleukin-6 receptor subunit beta CHLORIDE ION[1 atoms] pdb_complex 323 610 metal 3l5j 100.0 B 1 B IL6RB_HUMAN F 1 B CL 434:513-516 Interleukin-6 receptor subunit beta CHLORIDE ION[1 atoms] pdb_complex 323 610 metal 3l5j 100.0 B 1 B IL6RB_HUMAN G 1 B CL 559:565:589:591 Interleukin-6 receptor subunit beta CHLORIDE ION[1 atoms] pdb_complex 24 612 otherpoly 3l5h 100.0 A 1 A IL6RB_HUMAN B 1 B 226:227 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. pdb_complex 24 612 otherpoly 3l5h 100.0 A 1 A IL6RB_HUMAN D 1 D 82:83:85 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. pdb_complex 24 612 otherpoly 3l5h 100.0 A 1 A IL6RB_HUMAN H 1 H 43 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. pdb_complex 24 321 otherpoly 7u7n 100.0 B 1 B IL6RB_HUMAN E 1 E 43 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. pdb_complex 24 612 otherpoly 8d82 100.0 C 1 A IL6RB_HUMAN H 1 F 49:82:83:86 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. pdb_complex 24 612 otherpoly 8d82 100.0 C 1 A IL6RB_HUMAN I 1 I 552:553:569:596-598 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. pdb_complex 24 612 otherpoly 8d82 100.0 C 1 A IL6RB_HUMAN K 1 K 131 Interleukin-6 receptor subunit beta 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. pdb_complex 24 612 otherpoly 3l5h 100.0 A 1 A IL6RB_HUMAN C 1 C 157 Interleukin-6 receptor subunit beta beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1.. pdb_complex 24 612 otherpoly 3l5h 100.0 A 1 A IL6RB_HUMAN F 1 F 552:553:597-599 Interleukin-6 receptor subunit beta beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1.. pdb_complex 24 612 otherpoly 3l5h 100.0 A 1 A IL6RB_HUMAN E 1 E 363:364:383 Interleukin-6 receptor subunit beta beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. pdb_complex 24 321 otherpoly 7u7n 100.0 B 1 B IL6RB_HUMAN G 1 G 61:64 Interleukin-6 receptor subunit beta beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. pdb_complex 24 321 otherpoly 7u7n 100.0 B 1 B IL6RB_HUMAN H 1 H 108 Interleukin-6 receptor subunit beta beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. pdb_complex 24 612 otherpoly 3l5h 100.0 A 1 A IL6RB_HUMAN G 1 G 367:379 Interleukin-6 receptor subunit beta alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-bet.. pdb_complex 24 321 otherpoly 7u7n 100.0 B 1 B IL6RB_HUMAN F 1 F 30:83:85 Interleukin-6 receptor subunit beta alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(.. pdb_complex 123 332 homo 1bqu 99.5 A 1 A IL6RB_HUMAN B 1 B IL6RB_HUMAN 187:189:191:250-252:254:303:304 PROTEIN (GP130) PROTEIN (GP130)[215 aa] pdb_complex 122 333 homo 1bqu 99.5 B 1 B IL6RB_HUMAN A 1 A IL6RB_HUMAN 256:258:271:273-275:278:300:305:307:310 PROTEIN (GP130) PROTEIN (GP130)[208 aa] pdb_complex 123 332 precipitant 1bqu 99.5 A 1 A IL6RB_HUMAN F 1 A GOL 174:175:178:181-183 PROTEIN (GP130) GLYCEROL[6 atoms] pdb_complex 123 332 precipitant 1bqu 99.5 A 1 A IL6RB_HUMAN G 1 A GOL 138:223:224:226:245-248 PROTEIN (GP130) GLYCEROL[6 atoms] pdb_complex 122 333 precipitant 1bqu 99.5 B 1 B IL6RB_HUMAN L 1 B GOL 133-135:143:145:309 PROTEIN (GP130) GLYCEROL[6 atoms] pdb_complex 122 333 precipitant 1bqu 99.5 B 1 B IL6RB_HUMAN M 1 B GOL 141:185-187 PROTEIN (GP130) GLYCEROL[6 atoms] pdb_complex 123 332 precipitant 1bqu 99.5 A 1 A IL6RB_HUMAN C 1 A SO4 245:246:250:282 PROTEIN (GP130) SULFATE ION[5 atoms] pdb_complex 123 332 precipitant 1bqu 99.5 A 1 A IL6RB_HUMAN E 1 A SO4 300:310 PROTEIN (GP130) SULFATE ION[5 atoms] pdb_complex 122 333 precipitant 1bqu 99.5 B 1 B IL6RB_HUMAN I 1 B SO4 269:298 PROTEIN (GP130) SULFATE ION[5 atoms] pdb_complex 122 333 precipitant 1bqu 99.5 B 1 B IL6RB_HUMAN J 1 B SO4 281:284:285 PROTEIN (GP130) SULFATE ION[5 atoms] pdb_complex 24 612 precipitant 3l5h 100.0 A 1 A IL6RB_HUMAN I 1 A SO4 143 Interleukin-6 receptor subunit beta SULFATE ION[5 atoms] pdb_complex 24 612 precipitant 3l5h 100.0 A 1 A IL6RB_HUMAN J 1 A SO4 298 Interleukin-6 receptor subunit beta SULFATE ION[5 atoms] pdb_complex 24 612 precipitant 3l5h 100.0 A 1 A IL6RB_HUMAN K 1 A SO4 395 Interleukin-6 receptor subunit beta SULFATE ION[5 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN B 1 A EDO 459:492 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN C 1 A EDO 434:512:513:516:550 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN D 1 A EDO 557-559:565:589-591:605 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN E 1 A EDO 421-424:500:502:504:505 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN F 1 A EDO 557:591:593:595:600:602 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN G 1 A EDO 445:448-450:475 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN H 1 A EDO 424-426:428 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN I 1 A EDO 456-458:468:493-495 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN L 1 A EDO 363:364:366:383:384 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN M 1 A EDO 333-335:504 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN N 1 A EDO 384-386 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN P 1 A EDO 438:439:482:484-486 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN R 1 A EDO 529:531:534:536:578 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN S 1 A EDO 560:581-583:588 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms] pdb_complex 323 612 precipitant 3l5i 100.0 A 1 A IL6RB_HUMAN U 1 A EDO 577:578 Interleukin-6 receptor subunit beta 1,2-ETHANEDIOL[4 atoms]