type start end name pdb_id identity asym_id_homo oper_homo auth_asym_id_homo mol_id_homo asym_id_con oper_con auth_asym_id_con mol_id_con sites description_homo description_con length 1 740 id 1 740 DDX1_HUMAN title 1 740 RecName: Full=ATP-dependent RNA helicase DDX1; EC=3.6.4.13 ;AltName: Full=DEAD box protein 1;AltName: Full=DEAD box protein retinoblastoma; Short=DBP-RB; seq 1 740 MAAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQIVYETLKDQQEGKKGKTTIKTGASVLNKWQMNPYDRGSAFAIGSDGLCCQSREVKEWHGCRATKGLMKGKHYYEVSCHDQGLCRVGWSTMQASLDLGTDKFGFGFGGTGKKSHNKQFDNYGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQALFPACVLKNAELKFNFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLSEIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGSYKGHVDILAPTVQELAALEKEAQTSFLHLGYLPNQLFRTF uniprot 1 740 CHAIN /note="ATP-dependent RNA helicase DDX1" /id="PRO_0000054986" uniprot 2 428 DOMAIN /note="Helicase ATP-binding" uniprot 70 247 DOMAIN /note="B30.2/SPRY" uniprot 493 681 DOMAIN /note="Helicase C-terminal" uniprot 1 525 REGION /note="Necessary for interaction with RELA" uniprot 1 448 REGION /note="Interaction with dsRNA" uniprot 1 295 REGION /note="Necessary for interaction with HNRNPK" uniprot 525 740 REGION /note="Necessary for interaction with HNRNPK" uniprot 536 631 REGION /note="Necessary for interaction with replicase polyprotein 1ab nsp14 of IBV" uniprot 46 53 BINDING /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" disorder 1 1 predicted_by_DISOPRED disorder 160 172 predicted_by_DISOPRED disorder 181 181 predicted_by_DISOPRED disorder 460 492 predicted_by_DISOPRED disorder 640 656 predicted_by_DISOPRED disorder 658 658 predicted_by_DISOPRED disorder 661 663 predicted_by_DISOPRED disorder 665 665 predicted_by_DISOPRED disorder 672 677 predicted_by_DISOPRED disorder 681 711 predicted_by_DISOPRED disorder 714 715 predicted_by_DISOPRED disorder 717 718 predicted_by_DISOPRED pdb_monomer 1 673 monomer 8tbx 100.0 A A DDX1_HUMAN:DDX1_HUMAN 1-71:286-673 pdb_monomer 86 279 monomer 4xw3 100.0 B B A3RJH1_HUMAN 86-279 pdb_complex 1 673 compound 8tbx 100.0 A 1 A DDX1_HUMAN:DDX1_HUMAN B 1 A ADP 21:22:24-26:29:47-54:301 ATP-dependent RNA helicase DDX1 ADENOSINE-5'-DIPHOSPHATE[27 atoms] pdb_complex 1 673 metal 8tbx 100.0 A 1 A DDX1_HUMAN:DDX1_HUMAN C 1 A MG 53:370:371 ATP-dependent RNA helicase DDX1 MAGNESIUM ION[1 atoms] pdb_complex 1 673 metal 8tbx 100.0 A 1 A DDX1_HUMAN:DDX1_HUMAN D 1 A ZN 629:631:638:649 ATP-dependent RNA helicase DDX1 ZINC ION[1 atoms]