type start end name pdb_id identity asym_id_homo oper_homo auth_asym_id_homo mol_id_homo asym_id_con oper_con auth_asym_id_con mol_id_con sites description_homo description_con length 1 1255 id 1 1255 SPIKE_SARS title 1 1255 RecName: Full=Spike glycoprotein ; Short=S glycoprotein ;AltName: Full=E2 ;AltName: Full=Peplomer protein ;Contains: RecName: Full=Spike protein S1 ;Contains: RecName: Full=Spike protein S2 ;Contains: RecName: Full=Spike protein S2' ;Flags: Precursor; seq 1 1255 MFIFLLFLTLTSGSDLDRCTTFDDVQAPNYTQHTSSMRGVYYPDEIFRSDTLYLTQDLFLPFYSNVTGFHTINHTFGNPVIPFKDGIYFAATEKSNVVRGWVFGSTMNNKSQSVIIINNSTNVVIRACNFELCDNPFFAVSKPMGTQTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHLREFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLGINITNFRAILTAFSPAQDIWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVVRFPNITNLCPFGEVFNATKFPSVYAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSNVYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFMGCVLAWNTRNIDATSTGNYNYKYRYLRHGKLRPFERDISNVPFSPDGKPCTPPALNCYWPLNDYGFYTTTGIGYQPYRVVVLSFELLNAPATVCGPKLSTDLIKNQCVNFNFNGLTGTGVLTPSSKRFQPFQQFGRDVSDFTDSVRDPKTSEILDISPCSFGGVSVITPGTNASSEVAVLYQDVNCTDVSTAIHADQLTPAWRIYSTGNNVFQTQAGCLIGAEHVDTSYECDIPIGAGICASYHTVSLLRSTSQKSIVAYTMSLGADSSIAYSNNTIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFCTQLNRALSGIAAEQDRNTREVFAQVKQMYKTPTLKYFGGFNFSQILPDPLKPTKRSFIEDLLFNKVTLADAGFMKQYGECLGDINARDLICAQKFNGLTVLPPLLTDDMIAAYTAALVSGTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPAICHEGKAYFPREGVFVFNGTSWFITQRNFFSPQIITTDNTFVSGNCDVVIGIINNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYVWLGFIAGLIAIVMVTILLCCMTSCCSCLKGACSCGSCCKFDEDDSEPVLKGVKLHYT uniprot 1 13 SIGNAL uniprot 14 1255 CHAIN /note="Spike glycoprotein" /id="PRO_0000037208" uniprot 14 667 CHAIN /note="Spike protein S1" /id="PRO_0000037209" uniprot 668 1255 CHAIN /note="Spike protein S2" /id="PRO_0000037210" uniprot 798 1255 CHAIN /note="Spike protein S2'" /id="PRO_0000444082" uniprot 14 1195 TOPO_DOM /note="Extracellular" uniprot 1196 1216 TRANSMEM /note="Helical" uniprot 1217 1255 TOPO_DOM /note="Cytoplasmic" uniprot 14 290 DOMAIN /note="BetaCoV S1-NTD" uniprot 321 513 DOMAIN /note="BetaCoV S1-CTD" uniprot 306 527 REGION /note="Receptor-binding domain (RBD)" uniprot 424 494 REGION /note="Receptor-binding motif; binding to human ACE2" uniprot 798 819 REGION /note="Fusion peptide 1" ECO:0000305|PubMed:29056462" uniprot 817 837 REGION /note="Fusion peptide 2" ECO:0000305|PubMed:29056462" uniprot 902 952 REGION /note="Heptad repeat 1" uniprot 1145 1184 REGION /note="Heptad repeat 2" disorder 1 26 predicted_by_DISOPRED disorder 665 674 predicted_by_DISOPRED disorder 1003 1003 predicted_by_DISOPRED disorder 1005 1006 predicted_by_DISOPRED disorder 1253 1255 predicted_by_DISOPRED pdb_monomer 18 1119 monomer 6acc 100.0 C C SPIKE_CVHSA 18-1119 pdb_complex 18 1119 hetero 6acg 100.0 C 1 C SPIKE_CVHSA D 1 D ACE2_HUMAN 426:436:440:442:443:472:473:475:482:484:486-489:491:492 Spike glycoprotein Angiotensin-converting enzyme 2[597 aa] pdb_complex 32 1119 compound 7zh5 100.0 A 1 A SPIKE_SARS:WAC_BPT4 D 1 A NAG 32:63:65 Spike glycoprotein,Fibritin 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 32 1119 compound 7zh5 100.0 A 1 A SPIKE_SARS:WAC_BPT4 E 1 A NAG 158 Spike glycoprotein,Fibritin 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 32 1119 compound 7zh5 100.0 A 1 A SPIKE_SARS:WAC_BPT4 F 1 A NAG 105:227 Spike glycoprotein,Fibritin 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 32 1119 compound 7zh5 100.0 A 1 A SPIKE_SARS:WAC_BPT4 G 1 A NAG 269 Spike glycoprotein,Fibritin 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 32 1119 compound 7zh5 100.0 A 1 A SPIKE_SARS:WAC_BPT4 H 1 A NAG 691:1112 Spike glycoprotein,Fibritin 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 32 1119 compound 7zh5 100.0 A 1 A SPIKE_SARS:WAC_BPT4 I 1 A NAG 698:699:908:1053 Spike glycoprotein,Fibritin 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 32 1119 compound 7zh5 100.0 A 1 A SPIKE_SARS:WAC_BPT4 J 1 A NAG 778:783:785:786 Spike glycoprotein,Fibritin 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 32 1119 compound 7zh5 100.0 A 1 A SPIKE_SARS:WAC_BPT4 K 1 A NAG 1054:1056 Spike glycoprotein,Fibritin 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 32 1119 compound 7zh5 100.0 A 1 A SPIKE_SARS:WAC_BPT4 L 1 A NAG 1080:1083:1085 Spike glycoprotein,Fibritin 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 32 1119 compound 7zh5 100.0 A 1 A SPIKE_SARS:WAC_BPT4 N 1 B NAG 831-833 Spike glycoprotein,Fibritin 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 32 1119 compound 7zh5 100.0 A 1 A SPIKE_SARS:WAC_BPT4 T 1 C NAG 447 Spike glycoprotein,Fibritin 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1119 compound 7zh5 100.0 C 1 C SPIKE_SARS:WAC_BPT4 V 1 C NAG 602 Spike glycoprotein,Fibritin 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1121 compound 8h15 100.0 A 1 A SPIKE_SARS D 1 A NAG 105:227 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1121 compound 8h15 100.0 A 1 A SPIKE_SARS E 1 A NAG 267-269 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1121 compound 8h15 100.0 A 1 A SPIKE_SARS G 1 A NAG 778:783:785:786 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1121 compound 8h15 100.0 A 1 A SPIKE_SARS J 1 B NAG 338 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1121 compound 8h15 100.0 B 1 B SPIKE_SARS J 1 B NAG 158 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1121 compound 8h15 100.0 B 1 B SPIKE_SARS L 1 B NAG 318:566 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1121 compound 8h15 100.0 B 1 B SPIKE_SARS U 1 C NAG 544 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1121 compound 8h15 100.0 C 1 C SPIKE_SARS T 1 C NAG 1116 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1123 compound 8h16 100.0 A 1 B SPIKE_SARS G 1 B NAG 602:604 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1123 compound 8h16 100.0 A 1 B SPIKE_SARS H 1 B NAG 691:1113 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1123 compound 8h16 100.0 A 1 B SPIKE_SARS K 1 B NAG 1054:1056 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1123 compound 8h16 100.0 A 1 B SPIKE_SARS R 1 A NAG 832 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1123 compound 8h16 100.0 C 1 C SPIKE_SARS G 1 B NAG 833 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1123 compound 8h16 100.0 C 1 C SPIKE_SARS K 1 B NAG 877 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1123 compound 8h16 100.0 C 1 C SPIKE_SARS X 1 C NAG 32:65 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 31 1123 compound 8h16 100.0 C 1 C SPIKE_SARS Z 1 C NAG 119:121:122 Spike glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. pdb_complex 33 1120 homo 5xlr 100.0 A 1 A SPIKE_CVHSA B 1 B SPIKE_CVHSA 42:45-48:110:191-193:228:270:719:721:722:727:737-741:744:747:750:769-772:818:835-837:839:841:843-846:848:855:868:869:871:872:875-879:882:886:889:894:896:899:900:945:948:949:960:964-967:984:987:1001:1012:1013:1016 Spike glycoprotein Spike glycoprotein[1022 aa] pdb_complex 33 1120 homo 5xlr 100.0 A 1 A SPIKE_CVHSA C 1 C SPIKE_CVHSA 289:301:304:306:368-370:373:450-452:456:502:503:505:533:545:548:549:551-558:574:575:578:600:601:632:651-655:680:681:683-685:687:689:693-695:943:947:950-952:984:988:1021-1023:1027-1029:1051:1054:1056:1059:1061:1071:1073:1076:1077:1089:1103:1105:1108-1111 Spike glycoprotein Spike glycoprotein[1022 aa] pdb_complex 32 1119 homo 7zh5 100.0 A 1 A SPIKE_SARS:WAC_BPT4 B 1 B SPIKE_SARS:WAC_BPT4 42:44-48:110:189:191-193:221:223-227:269:719:737-741:744:747:750:768-772:776:779:833:835-837:839:841:845-848:851:854:855:865:866:872:874:876-879:882:886:895:896:899:900:902:945:948:949:957:958:960:964-967:970:976:987:1001:1012:1013:1021 Spike glycoprotein,Fibritin Spike glycoprotein,Fibritin[926 aa] pdb_complex 31 1119 homo 7zh5 100.0 C 1 C SPIKE_SARS:WAC_BPT4 B 1 B SPIKE_SARS:WAC_BPT4 304:306:533:535:544-546:548-554:556:558:573:575-578:600:651:653-655:681:683:685-691:693-695:697:939:943:946:947:950:951:953:992:999:1021-1023:1027-1029:1054:1059-1061:1071-1073:1089:1103:1105:1112 Spike glycoprotein,Fibritin Spike glycoprotein,Fibritin[926 aa] pdb_complex 32 1119 homo 7zh5 100.0 A 1 A SPIKE_SARS:WAC_BPT4 C 1 C SPIKE_SARS:WAC_BPT4 304:306:368-370:373:377:383:413:417:449:451-453:502:533:543:544:548-553:555-558:574-578:600:632:651-655:679:681:683-685:687-689:691:693-695:939:943:947:950-952:988:999:1021-1023:1027-1029:1054:1059:1061:1071:1072:1076:1089:1103:1105:1110 Spike glycoprotein,Fibritin Spike glycoprotein,Fibritin[962 aa] pdb_complex 31 1119 homo 7zh5 100.0 C 1 C SPIKE_SARS:WAC_BPT4 A 1 A SPIKE_SARS:WAC_BPT4 42:45-50:189-193:218:221:223-227:269:719:722:727:737-741:744:747:769-772:779:835-839:844-848:851:855:865:866:869:871:872:875-879:882:886:895:896:899:900:945:960:963-965:967:987:1001:1012:1013:1021 Spike glycoprotein,Fibritin Spike glycoprotein,Fibritin[904 aa] pdb_complex 31 1123 homo 8h16 100.0 A 1 B SPIKE_SARS B 1 A SPIKE_SARS 42:45-47:51:217:218:269:271:719:721:737-740:744:747:769-772:779:818:822:823:835-837:841:843:845:846:848:851:855:865:868:872:875-880:882:886:896:899:900:945:948:976:984:987:994:1001:1012:1013:1021:1100 Spike glycoprotein Spike glycoprotein[805 aa] pdb_complex 31 1123 homo 8h16 100.0 C 1 C SPIKE_SARS B 1 A SPIKE_SARS 304:306:342:368-370:373:377:383:450-453:455:502:503:505:531:533:535:543-546:548:549:551-553:555-558:575:577:578:600:651:653-655:679:681:683-691:693-695:697:943:946:947:950-953:984:999:1021:1022:1027-1029:1054:1056:1059:1071:1089:1105:1110 Spike glycoprotein Spike glycoprotein[805 aa]