type start end name pdb_id identity asym_id_homo oper_homo auth_asym_id_homo mol_id_homo asym_id_con oper_con auth_asym_id_con mol_id_con sites description_homo description_con length 1 317 id 1 317 APOE_HUMAN title 1 317 RecName: Full=Apolipoprotein E ; Short=Apo-E;Flags: Precursor; seq 1 317 MKVLWAALLVTFLAGCQAKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGTSAAPVPSDNH uniprot 1 18 SIGNAL uniprot 19 317 CHAIN /note="Apolipoprotein E" /id="PRO_0000001987" uniprot 80 255 REGION /note="8 X 22 AA approximate tandem repeats" uniprot 158 168 REGION /note="LDL and other lipoprotein receptors binding" ECO:0000269|PubMed:2063194" uniprot 210 290 REGION /note="Lipid-binding and lipoprotein association" ECO:0000269|PubMed:8071364" uniprot 266 317 REGION /note="Homooligomerization" uniprot 278 290 REGION /note="Specificity for association with VLDL" uniprot 162 165 BINDING /ligand="heparin" /ligand_id="ChEBI:CHEBI:28304" uniprot 229 236 BINDING /ligand="heparin" /ligand_id="ChEBI:CHEBI:28304" disorder 1 36 predicted_by_DISOPRED disorder 304 317 predicted_by_DISOPRED pdb_monomer 19 317 monomer 2l7b 98.3 A A APOE_HUMAN 19-317 pdb_complex 41 182 hetero 6iwb 91.5 A 1 A APOE_HUMAN B 1 B BCL2_HUMAN:BCL2_HUMAN 45:49:52:53:55:56:59:121:132:149:153:156-158:160-165:167-169:171:172 Apolipoprotein E Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-.. pdb_complex 41 180 hetero 8grx 99.3 A 1 A APOE_HUMAN B 1 B LIRA6_HUMAN 127:128:131:132:135:139:142-144:151:154:158:161:162:165 Apolipoprotein E Leukocyte immunoglobulin-like receptor subfamily A.. pdb_complex 41 180 hetero 8grx 99.3 A 1 A APOE_HUMAN D 1 D LIRA6_HUMAN 46:50:53:54:56:57:64:68 Apolipoprotein E Leukocyte immunoglobulin-like receptor subfamily A.. pdb_complex 36 99 hetero 6v7m 100.0 A 1 A APOE_HUMAN B 1 B APOE_HUMAN 36:39:44:48:51:52:55:56:58:59:61:66:69-71:74:75:78:79:82:85:86:89:90:93:96:97:99 Apolipoprotein E Apolipoprotein E[83 aa] pdb_complex 101 183 hetero 6v7m 100.0 B 1 B APOE_HUMAN A 1 A APOE_HUMAN 108:112:115:119:126:127:129:130:133:136:137:140:152:155:156:159:160:163:166:167:170:173-175:177:178:180:181 Apolipoprotein E Apolipoprotein E[64 aa] pdb_complex 42 182 compound 6ncn 99.3 A 1 A APOE_HUMAN B 1 A KJM 44:45:48:52:167:170:171:174 Apolipoprotein E 1-(3-chlorophenyl)cyclobutane-1-carboximidamide[14.. pdb_complex 42 182 compound 6nco 99.3 A 1 A APOE_HUMAN B 1 A KQP 44-46:48:49:52:53:167:170:171:174 Apolipoprotein E 1-[5-chloro-4'-(2-hydroxypropan-2-yl)[1,1'-bipheny.. pdb_complex 41 181 metal 7fcr 99.3 A 1 A APOE_HUMAN B 1 A NA 53:56 Apolipoprotein E SODIUM ION[1 atoms] pdb_complex 41 181 metal 7fcr 99.3 A 1 A APOE_HUMAN C 1 A NA 147-151 Apolipoprotein E SODIUM ION[1 atoms] pdb_complex 41 181 metal 7fcs 99.3 A 1 A APOE_HUMAN B 1 A NA 132:136:139 Apolipoprotein E SODIUM ION[1 atoms] pdb_complex 94 266 homo 6clz 28.5 B 1 B APOA1_HUMAN C 1 C APOA1_HUMAN 96:100:111:115:118:129:133:143:147:151:154:155:158:159:162:184:195:198:202:205:206:212:215:216:218:219:224:227:228:231:232:235:242:246:250:253:257:264 Apolipoprotein A-I Apolipoprotein A-I[211 aa] pdb_complex 94 266 precipitant 6clz 28.5 B 1 B APOA1_HUMAN BB 1 B PX4 140:141:144 Apolipoprotein A-I 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE[46 ato.. pdb_complex 94 266 precipitant 6clz 28.5 B 1 B APOA1_HUMAN CD 1 B PX4 97 Apolipoprotein A-I 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE[46 ato.. pdb_complex 94 266 precipitant 6clz 28.5 C 1 C APOA1_HUMAN BB 1 B PX4 231 Apolipoprotein A-I 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE[46 ato.. pdb_complex 94 266 precipitant 6cm1 28.5 B 1 B APOA1_HUMAN JF 1 C PX4 158:162 Apolipoprotein A-I 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE[46 ato.. pdb_complex 41 182 precipitant 6iwb 91.5 A 1 A APOE_HUMAN E 1 A SO4 132:154:158 Apolipoprotein E SULFATE ION[5 atoms] pdb_complex 41 182 precipitant 6iwb 91.5 A 1 A APOE_HUMAN F 1 A SO4 79:130 Apolipoprotein E SULFATE ION[5 atoms] pdb_complex 40 183 precipitant 7uvj 96.5 A 1 A APOE_HUMAN D 1 A PEG 97:112:180 Apolipoprotein E DI(HYDROXYETHYL)ETHER[7 atoms] pdb_complex 40 183 precipitant 7uvj 96.5 B 1 B APOE_HUMAN G 1 B PEG 158:161 Apolipoprotein E DI(HYDROXYETHYL)ETHER[7 atoms] pdb_complex 40 183 precipitant 7uvj 96.5 A 1 A APOE_HUMAN E 1 A ACT 116 Apolipoprotein E ACETATE ION[4 atoms] pdb_complex 40 183 precipitant 7uvj 96.5 A 1 A APOE_HUMAN C 1 A GOL 73:77 Apolipoprotein E GLYCEROL[6 atoms] pdb_complex 40 183 precipitant 7uvj 96.5 B 1 B APOE_HUMAN F 1 B GOL 117:121 Apolipoprotein E GLYCEROL[6 atoms] pdb_complex 41 183 precipitant 8ce0 99.3 A 1 A A0A376KDN7_ECOLX:APOE_HUMAN B 1 A GOL 59:149:152:153:156 Maltodextrin-binding protein,Apolipoprotein E GLYCEROL[6 atoms] pdb_complex 36 99 precipitant 6v7m 100.0 A 1 A APOE_HUMAN C 1 A PO4 52:56 Apolipoprotein E PHOSPHATE ION[5 atoms] pdb_complex 101 183 precipitant 6v7m 100.0 B 1 B APOE_HUMAN C 1 A PO4 163:167 Apolipoprotein E PHOSPHATE ION[5 atoms]