type start end name pdb_id identity asym_id_homo oper_homo auth_asym_id_homo mol_id_homo asym_id_con oper_con auth_asym_id_con mol_id_con sites description_homo description_con length 1 740 id 1 740 DDX1_HUMAN title 1 740 RecName: Full=ATP-dependent RNA helicase DDX1; EC=3.6.4.13 ;AltName: Full=DEAD box protein 1;AltName: Full=DEAD box protein retinoblastoma; Short=DBP-RB; seq 1 740 MAAFSEMGVMPEIAQAVEEMDWLLPTDIQAESIPLILGGGDVLMAAETGSGKTGAFSIPVIQIVYETLKDQQEGKKGKTTIKTGASVLNKWQMNPYDRGSAFAIGSDGLCCQSREVKEWHGCRATKGLMKGKHYYEVSCHDQGLCRVGWSTMQASLDLGTDKFGFGFGGTGKKSHNKQFDNYGEEFTMHDTIGCYLDIDKGHVKFSKNGKDLGLAFEIPPHMKNQALFPACVLKNAELKFNFGEEEFKFPPKDGFVALSKAPDGYIVKSQHSGNAQVTQTKFLPNAPKALIVEPSRELAEQTLNNIKQFKKYIDNPKLRELLIIGGVAARDQLSVLENGVDIVVGTPGRLDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSATLHSFDVKKLSEKIMHFPTWVDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRTDDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQAIIFCRTKIDCDNLEQYFIQQGGGPDKKGHQFSCVCLHGDRKPHERKQNLERFKKGDVRFLICTDVAARGIDIHGVPYVINVTLPDEKQNYVHRIGRVGRAERMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKEDGGCTIWYNEMQLLSEIEEHLNCTISQVEPDIKVPVDEFDGKVTYGQKRAAGGGSYKGHVDILAPTVQELAALEKEAQTSFLHLGYLPNQLFRTF uniprot 1 740 CHAIN /note="ATP-dependent RNA helicase DDX1" /id="PRO_0000054986" uniprot 2 428 DOMAIN /note="Helicase ATP-binding" uniprot 70 247 DOMAIN /note="B30.2/SPRY" uniprot 493 681 DOMAIN /note="Helicase C-terminal" uniprot 1 525 REGION /note="Necessary for interaction with RELA" uniprot 1 448 REGION /note="Interaction with dsRNA" uniprot 1 295 REGION /note="Necessary for interaction with HNRNPK" uniprot 525 740 REGION /note="Necessary for interaction with HNRNPK" uniprot 536 631 REGION /note="Necessary for interaction with replicase polyprotein 1ab nsp14 of IBV" uniprot 46 53 BINDING /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" disorder 1 1 predicted_by_DISOPRED disorder 160 172 predicted_by_DISOPRED disorder 181 181 predicted_by_DISOPRED disorder 460 492 predicted_by_DISOPRED disorder 640 656 predicted_by_DISOPRED disorder 658 658 predicted_by_DISOPRED disorder 661 663 predicted_by_DISOPRED disorder 665 665 predicted_by_DISOPRED disorder 672 677 predicted_by_DISOPRED disorder 681 711 predicted_by_DISOPRED disorder 714 715 predicted_by_DISOPRED disorder 717 718 predicted_by_DISOPRED pdb_monomer 1 673 monomer 8tbx 100.0 A A DDX1_HUMAN:DDX1_HUMAN 1-71:286-673 pdb_monomer 86 279 monomer 4xw3 100.0 B B A3RJH1_HUMAN 86-279 pdb_monomer 86 275 monomer 4xw3 100.0 A A A3RJH1_HUMAN 86-275 pdb_monomer 509 618 monomer 2jgn 44.9 C C DDX3X_HUMAN 509-530:540-618 pdb_monomer 507 620 monomer 2hjv 47.6 A A DBPA_BACSU 507-530:540-620 pdb_monomer 507 621 monomer 2hjv 47.2 B B DBPA_BACSU 507-530:540-621 pdb_monomer 493 626 monomer 5gi4 40.0 B B DEAD_ECOLI 493-530:540-626 pdb_monomer 493 626 monomer 5gi4 40.0 A A DEAD_ECOLI 493-530:540-626 pdb_monomer 499 625 monomer 7bbb 41.5 A A DBPA_ECOLI 499-531:541-625 pdb_monomer 508 622 monomer 1fuk 42.6 A A IF4A_YEAST 508-526:536-622 pdb_monomer 494 625 monomer 5nt7 40.2 A B VASA1_DROME 494-529:539-625 pdb_monomer 494 625 monomer 5nt7 40.2 D D VASA1_DROME 494-529:539-625 pdb_monomer 509 618 monomer 2jgn 41.7 B B DDX3X_HUMAN 509-530:540-618 pdb_monomer 507 625 monomer 3ear 40.2 A A Q72GF3_THET2 507-530:540-625 pdb_monomer 509 618 monomer 7ymf 40.9 B B DDX3X_HUMAN 509-530:540-618 pdb_monomer 509 619 monomer 2kbf 46.1 A A DBP5_YEAST 509-523:531-542:545-619 pdb_monomer 509 619 monomer 3gfp 46.1 A A DBP5_YEAST 509-523:531-542:545-619 pdb_monomer 4 429 monomer 5gju 40.4 A A DEAD_ECOLI 4-72:286-329:332-395:402-412:414-429 pdb_monomer 507 605 monomer 3i32 41.1 A A Q72GF3_THET2 507-530:540-605 pdb_monomer 507 602 monomer 3eaq 42.5 A A Q72GF3_THET2 507-530:540-602 pdb_monomer 508 623 monomer 2rb4 41.7 A A DDX25_HUMAN 508-530:538-542:545-623 pdb_monomer 507 602 monomer 3eas 42.5 A A Q72GF3_THET2 507-530:540-602 pdb_monomer 509 618 monomer 2jgn 40.2 A A DDX3X_HUMAN 509-530:540-618 pdb_monomer 508 623 monomer 2rb4 42.2 B B DDX25_HUMAN 508-530:538-542:545-623 pdb_monomer 507 601 monomer 3eas 41.9 B B Q72GF3_THET2 507-530:540-601 pdb_monomer 507 601 monomer 3eaq 41.9 B B Q72GF3_THET2 507-530:540-601 pdb_monomer 545 620 monomer 8v84 46.1 C 3 DBP10_YEAST 545-620 pdb_monomer 508 626 monomer 6yvh 40.6 F H IF4A3_HUMAN 508-526:536-626 pdb_monomer 4 611 monomer 7ohx 43.4 I D HAS1_YEAST 4-65:545-611 pdb_monomer 4 611 monomer 5z3g 43.4 Y Y HAS1_YEAST 4-65:545-611 pdb_monomer 4 611 monomer 8e5t 43.4 U p HAS1_YEAST 4-65:545-611 pdb_monomer 4 611 monomer 6cb1 43.4 JA p A0A250WER3_YEASX 4-65:545-611 pdb_monomer 4 611 monomer 7ohw 43.4 J D HAS1_YEAST 4-65:545-611 pdb_monomer 4 611 monomer 6c0f 43.4 IA p HAS1_YEAST 4-65:545-611 pdb_monomer 4 611 monomer 7ohr 43.4 G D HAS1_YEAST 4-65:545-611 pdb_monomer 4 611 monomer 7ohv 43.4 G D HAS1_YEAST 4-65:545-611 pdb_monomer 4 611 monomer 7ohs 43.4 J D HAS1_YEAST 4-65:545-611 pdb_monomer 4 611 monomer 7r6q 43.4 B D HAS1_YEAST 4-65:545-611 pdb_monomer 509 619 monomer 3peu 46.0 A A DBP5_YEAST 509-523:531-542:545-619 pdb_monomer 509 619 monomer 3pev 46.0 A A DBP5_YEAST 509-523:531-542:545-619 pdb_monomer 4 607 monomer 8v87 44.0 J D HAS1_YEAST 4-65:545-607 pdb_monomer 4 607 monomer 7r7a 44.0 AB D HAS1_YEAST 4-65:545-607 pdb_monomer 4 607 monomer 7nac 44.0 AB D HAS1_YEAST 4-65:545-607 pdb_monomer 545 605 monomer 6em4 44.3 EA D HAS1_YEAST 545-605 pdb_monomer 545 605 monomer 6em3 44.3 AA D HAS1_YEAST 545-605 pdb_monomer 545 605 monomer 6em5 44.3 GA D HAS1_YEAST 545-605 pdb_monomer 545 605 monomer 6em1 44.3 NA D HAS1_YEAST 545-605 pdb_monomer 545 605 monomer 6elz 44.3 HA D HAS1_YEAST 545-605 pdb_monomer 13 604 monomer 8eti 41.9 J D HAS1_SCHPO 13-65:281-316:320-392:545-604 pdb_monomer 13 604 monomer 8eup 41.8 J D S6CCW7_SCHPM 13-65:281-316:320-392:545-604 pdb_complex 494 625 hetero 5nt7 40.2 A 1 B VASA1_DROME B 1 A OSKA_DROME 496:499:517:520:521:523-525:527-529:539:542-544:546-550:553:554:566 ATP-dependent RNA helicase vasa, isoform A Maternal effect protein oskar[92 aa] pdb_complex 494 625 hetero 5nt7 40.2 D 1 D VASA1_DROME C 1 C OSKA_DROME 496:499:517:520:521:523-525:527-529:539:542-544:546-550:553:554:566 ATP-dependent RNA helicase vasa, isoform A Maternal effect protein oskar[92 aa] pdb_complex 508 626 hetero 6yvh 40.6 F 1 H IF4A3_HUMAN A 1 A CWC22_HUMAN 538-541:564:565:567 Eukaryotic initiation factor 4A-III Pre-mRNA-splicing factor CWC22 homolog[274 aa] pdb_complex 508 626 hetero 6yvh 40.6 F 1 H IF4A3_HUMAN E 1 F CWC22_HUMAN 515-517:548:573-575:594:595:597:598:601 Eukaryotic initiation factor 4A-III Pre-mRNA-splicing factor CWC22 homolog[272 aa] pdb_complex 13 604 hetero 8eti 41.9 J 1 D HAS1_SCHPO GA 1 i RL36B_SCHPO 357:358:360 ATP-dependent RNA helicase has1 60S ribosomal protein L36-B[85 aa] pdb_complex 13 604 hetero 8eup 41.8 J 1 D S6CCW7_SCHPM DA 1 i RL36B_SCHPO 330:337:357:358 RNA helicase 60S ribosomal protein L36-B[98 aa] pdb_complex 545 605 hetero 6elz 44.3 HA 1 D HAS1_YEAST FA 1 K CIC1_YEAST 586 ATP-dependent RNA helicase HAS1 Proteasome-interacting protein CIC1[257 aa] pdb_complex 545 605 hetero 6em1 44.3 NA 1 D HAS1_YEAST LA 1 K CIC1_YEAST 586 ATP-dependent RNA helicase HAS1 Proteasome-interacting protein CIC1[257 aa] pdb_complex 509 619 hetero 3peu 46.0 A 1 A DBP5_YEAST B 1 B GLE1_YEAST 536-538:562-565:567:582:583:611 ATP-dependent RNA helicase DBP5 Nucleoporin GLE1[295 aa] pdb_complex 509 619 hetero 3peu 46.0 A 2 A DBP5_YEAST B 1 B GLE1_YEAST 513:514:547:554:572-574:594:595:597 ATP-dependent RNA helicase DBP5 Nucleoporin GLE1[295 aa] pdb_complex 509 619 hetero 3pev 46.0 A 1 A DBP5_YEAST B 1 B GLE1_YEAST 536-538:562:564:565:567:582:583:611 ATP-dependent RNA helicase DBP5 Nucleoporin GLE1[295 aa] pdb_complex 509 619 hetero 3pev 46.0 A 2 A DBP5_YEAST B 1 B GLE1_YEAST 513:514:547:554:572-574:594:595:597 ATP-dependent RNA helicase DBP5 Nucleoporin GLE1[295 aa] pdb_complex 545 620 hetero 8v84 46.1 C 1 3 DBP10_YEAST AA 1 V RL23A_YEAST 550:552:553:556 ATP-dependent RNA helicase DBP10 60S ribosomal protein L23-A[122 aa] pdb_complex 13 604 nucleotide 8eup 41.8 J 1 D S6CCW7_SCHPM A 1 1 303:307:327:328:330:331:335 RNA helicase RNA (1422-MER) pdb_complex 13 604 nucleotide 8eti 41.9 J 1 D HAS1_SCHPO A 1 1 327:328:330:331:335 ATP-dependent RNA helicase has1 RNA (1564-MER) pdb_complex 545 605 nucleotide 6elz 44.3 HA 1 D HAS1_YEAST A 1 1 548 ATP-dependent RNA helicase HAS1 25S ribosomal RNA pdb_complex 4 429 compound 5gju 40.4 A 1 A DEAD_ECOLI B 1 A AMP 4:22:24:26:29:48-53 ATP-dependent RNA helicase DeaD ADENOSINE MONOPHOSPHATE[23 atoms] pdb_complex 1 673 compound 8tbx 100.0 A 1 A DDX1_HUMAN:DDX1_HUMAN B 1 A ADP 21:22:24-26:29:47-54:301 ATP-dependent RNA helicase DDX1 ADENOSINE-5'-DIPHOSPHATE[27 atoms] pdb_complex 508 623 metal 2rb4 41.7 A 1 A DDX25_HUMAN C 1 A CL 577 ATP-dependent RNA helicase DDX25 CHLORIDE ION[1 atoms] pdb_complex 508 623 metal 2rb4 41.7 A 1 A DDX25_HUMAN D 1 A CL 515:516 ATP-dependent RNA helicase DDX25 CHLORIDE ION[1 atoms] pdb_complex 507 602 metal 3eaq 42.5 A 1 A Q72GF3_THET2 C 1 A CL 573:577:601 Heat resistant RNA dependent ATPase CHLORIDE ION[1 atoms] pdb_complex 507 601 metal 3eaq 41.9 B 1 B Q72GF3_THET2 D 1 B CL 591 Heat resistant RNA dependent ATPase CHLORIDE ION[1 atoms] pdb_complex 508 622 metal 1fuk 42.6 A 1 A IF4A_YEAST B 1 A ZN 597:600:601 EUKARYOTIC INITIATION FACTOR 4A ZINC ION[1 atoms] pdb_complex 508 623 metal 2rb4 41.7 A 1 A DDX25_HUMAN F 1 A ZN 575:601 ATP-dependent RNA helicase DDX25 ZINC ION[1 atoms] pdb_complex 1 673 metal 8tbx 100.0 A 1 A DDX1_HUMAN:DDX1_HUMAN D 1 A ZN 629:631:638:649 ATP-dependent RNA helicase DDX1 ZINC ION[1 atoms] pdb_complex 1 673 metal 8tbx 100.0 A 1 A DDX1_HUMAN:DDX1_HUMAN C 1 A MG 53:370:371 ATP-dependent RNA helicase DDX1 MAGNESIUM ION[1 atoms] pdb_complex 508 623 precipitant 2rb4 41.7 A 1 A DDX25_HUMAN E 1 A SO4 559:562 ATP-dependent RNA helicase DDX25 SULFATE ION[5 atoms] pdb_complex 508 623 precipitant 2rb4 42.2 B 1 B DDX25_HUMAN G 1 B SO4 559:562 ATP-dependent RNA helicase DDX25 SULFATE ION[5 atoms] pdb_complex 509 619 precipitant 3peu 46.0 A 1 A DBP5_YEAST C 1 A SO4 515:516 ATP-dependent RNA helicase DBP5 SULFATE ION[5 atoms] pdb_complex 509 619 precipitant 3peu 46.0 A 2 A DBP5_YEAST C 2 A SO4 515:516 ATP-dependent RNA helicase DBP5 SULFATE ION[5 atoms] pdb_complex 509 619 precipitant 3pev 46.0 A 1 A DBP5_YEAST C 1 A SO4 515:516 ATP-dependent RNA helicase DBP5 SULFATE ION[5 atoms] pdb_complex 509 619 precipitant 3pev 46.0 A 2 A DBP5_YEAST C 2 A SO4 515:516 ATP-dependent RNA helicase DBP5 SULFATE ION[5 atoms] pdb_complex 509 619 precipitant 3peu 46.0 A 1 A DBP5_YEAST D 1 A GOL 514:574:591-594:602 ATP-dependent RNA helicase DBP5 GLYCEROL[6 atoms] pdb_complex 509 619 precipitant 3peu 46.0 A 2 A DBP5_YEAST D 2 A GOL 514:574:591-594:602 ATP-dependent RNA helicase DBP5 GLYCEROL[6 atoms] pdb_complex 509 619 precipitant 3pev 46.0 A 1 A DBP5_YEAST D 1 A GOL 513:514:574:591-594:602 ATP-dependent RNA helicase DBP5 GLYCEROL[6 atoms] pdb_complex 509 619 precipitant 3pev 46.0 A 2 A DBP5_YEAST D 2 A GOL 513:514:574:591-594:602 ATP-dependent RNA helicase DBP5 GLYCEROL[6 atoms]