type start end name pdb_id identity asym_id_homo oper_homo auth_asym_id_homo mol_id_homo asym_id_con oper_con auth_asym_id_con mol_id_con sites description_homo description_con length 1 275 id 1 275 AP3A_SARS2 title 1 275 RecName: Full=ORF3a protein; Short=ORF3a;AltName: Full=Accessory protein 3a;AltName: Full=Protein 3a;AltName: Full=Protein U274;AltName: Full=Protein X1; seq 1 275 MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFGWLIVGVALLAVFQSASKIITLKKRWQLALSKGVHFVCNLLLLFVTVYSHLLLVAAGLEAPFLYLYALVYFLQSINFVRIIMRLWLCWKCRSKNPLLYDANYFLCWHTNCYDYCIPYNSVTSSIVITSGDGTTSPISEHDYQIGGYTEKWESGVKDCVVLHSYFTSDYYQLYSTQLSTDTGVEHVTFFIYNKIVDEPEEHVQIHTIDGSSGVVNPVMEPIYDEPTTTTSVPL uniprot 1 275 CHAIN /note="ORF3a protein" /id="PRO_0000449650" uniprot 1 42 TOPO_DOM /note="Extracellular" uniprot 43 61 TRANSMEM /note="Helical" uniprot 62 67 TOPO_DOM /note="Cytoplasmic" uniprot 68 93 TRANSMEM /note="Helical" uniprot 94 101 TOPO_DOM /note="Extracellular" uniprot 102 126 TRANSMEM /note="Helical" uniprot 127 275 TOPO_DOM /note="Cytoplasmic" uniprot 33 141 DOMAIN /note="CoV 3a-like viroporin TM" uniprot 145 237 DOMAIN /note="CoV 3a-like viroporin CD" uniprot 1 39 REGION /note="Disordered" uniprot 239 275 REGION /note="Disordered" disorder 1 6 predicted_by_DISOPRED disorder 8 8 predicted_by_DISOPRED disorder 10 15 predicted_by_DISOPRED disorder 267 275 predicted_by_DISOPRED pdb_monomer 40 238 monomer 7kjr 100.0 B B AP3A_SARS2 40-238 pdb_monomer 40 238 monomer 7kjr 100.0 A A AP3A_SARS2 40-238 pdb_monomer 40 238 monomer 6xdc 100.0 B B AP3A_SARS2 40-238 pdb_monomer 40 238 monomer 6xdc 100.0 A A AP3A_SARS2 40-238 pdb_monomer 40 238 monomer 8eqj 100.0 A A AP3A_SARS2 40-238 pdb_monomer 40 238 monomer 8eqj 100.0 B B AP3A_SARS2 40-238 pdb_monomer 40 238 monomer 8eqt 100.0 A A AP3A_SARS2 40-238 pdb_monomer 40 238 monomer 8eqt 100.0 B B AP3A_SARS2 40-238 pdb_monomer 40 237 monomer 8equ 100.0 B B AP3A_SARS2 40-237 pdb_monomer 40 237 monomer 8equ 100.0 A A AP3A_SARS2 40-237 pdb_monomer 40 237 monomer 8eqs 76.6 B B AP3A_SARS 40-237 pdb_monomer 40 237 monomer 8eqs 76.6 A A AP3A_SARS 40-237 pdb_complex 40 238 hetero 7kjr 100.0 A 1 A AP3A_SARS2 C 1 C APOA1_HUMAN 62-64:67:69:70 ORF3a protein Apolipoprotein A-I[31 aa] pdb_complex 40 238 hetero 7kjr 100.0 A 1 A AP3A_SARS2 D 1 D APOA1_HUMAN 121:125:128:132:206:207 ORF3a protein Apolipoprotein A-I[31 aa] pdb_complex 40 238 hetero 7kjr 100.0 B 1 B AP3A_SARS2 C 1 C APOA1_HUMAN 121:128:132:206:207 ORF3a protein Apolipoprotein A-I[31 aa] pdb_complex 40 238 hetero 7kjr 100.0 B 1 B AP3A_SARS2 D 1 D APOA1_HUMAN 62-64:67:69:70 ORF3a protein Apolipoprotein A-I[31 aa] pdb_complex 40 237 hetero 8eqs 76.6 A 1 A AP3A_SARS C 1 C APOA1_HUMAN 64:69:70 ORF3a protein Apolipoprotein A-I[27 aa] pdb_complex 40 237 hetero 8eqs 76.6 A 1 A AP3A_SARS D 1 D APOA1_HUMAN 128:206:207:209 ORF3a protein Apolipoprotein A-I[27 aa] pdb_complex 40 237 hetero 8eqs 76.6 B 1 B AP3A_SARS C 1 C APOA1_HUMAN 128:206:207:209 ORF3a protein Apolipoprotein A-I[27 aa] pdb_complex 40 237 hetero 8eqs 76.6 B 1 B AP3A_SARS D 1 D APOA1_HUMAN 64:69:70 ORF3a protein Apolipoprotein A-I[27 aa] pdb_complex 40 237 hetero 8equ 100.0 A 1 A AP3A_SARS2 C 1 C SAP_HUMAN 114:118:121:122:206-208 ORF3a protein Saposin-A[80 aa] pdb_complex 40 237 hetero 8equ 100.0 A 1 A AP3A_SARS2 F 1 F SAP_HUMAN 64 ORF3a protein Saposin-A[80 aa] pdb_complex 40 237 hetero 8equ 100.0 B 1 B AP3A_SARS2 C 1 C SAP_HUMAN 64 ORF3a protein Saposin-A[80 aa] pdb_complex 40 237 hetero 8equ 100.0 B 1 B AP3A_SARS2 F 1 F SAP_HUMAN 114:122:206-208 ORF3a protein Saposin-A[80 aa] pdb_complex 40 237 hetero 8equ 100.0 A 1 A AP3A_SARS2 D 1 D 107 ORF3a protein Saposin A, polyalanine model[79 aa] pdb_complex 40 237 hetero 8equ 100.0 B 1 B AP3A_SARS2 G 1 G 107 ORF3a protein Saposin A, polyalanine model[79 aa] pdb_complex 40 238 compound 7kjr 100.0 A 1 A AP3A_SARS2 E 1 A PEE 61-64 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a.. pdb_complex 40 238 compound 7kjr 100.0 A 1 A AP3A_SARS2 F 1 B PEE 118:121:122:206 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a.. pdb_complex 40 238 compound 7kjr 100.0 B 1 B AP3A_SARS2 E 1 A PEE 118:121:122:206 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a.. pdb_complex 40 238 compound 7kjr 100.0 B 1 B AP3A_SARS2 F 1 B PEE 61-64 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a.. pdb_complex 40 238 compound 8eqj 100.0 A 1 A AP3A_SARS2 C 1 A PEE 118:121:122:126:144:206 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a.. pdb_complex 40 238 compound 8eqj 100.0 A 1 A AP3A_SARS2 D 1 A PEE 75:76:78:79:122:123:140 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[22 a.. pdb_complex 40 238 compound 8eqj 100.0 A 1 A AP3A_SARS2 E 1 B PEE 62-64 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a.. pdb_complex 40 238 compound 8eqj 100.0 B 1 B AP3A_SARS2 C 1 A PEE 62-64 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a.. pdb_complex 40 238 compound 8eqj 100.0 B 1 B AP3A_SARS2 E 1 B PEE 118:121:122:126:144:206 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a.. pdb_complex 40 238 compound 8eqj 100.0 B 1 B AP3A_SARS2 F 1 B PEE 75:76:78:79:122:123:140 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[22 a.. pdb_complex 40 237 compound 8eqs 76.6 A 1 A AP3A_SARS E 1 A PEE 118:122:206:207 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[25 a.. pdb_complex 40 237 compound 8eqs 76.6 A 1 A AP3A_SARS F 1 B PEE 62-64:74 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[25 a.. pdb_complex 40 237 compound 8eqs 76.6 B 1 B AP3A_SARS E 1 A PEE 62-64:74 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[25 a.. pdb_complex 40 237 compound 8eqs 76.6 B 1 B AP3A_SARS F 1 B PEE 118:122:206:207 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[25 a.. pdb_complex 40 238 compound 8eqt 100.0 A 1 A AP3A_SARS2 C 1 A PEE 72:75:76:78:79:122:123 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[22 a.. pdb_complex 40 238 compound 8eqt 100.0 A 1 A AP3A_SARS2 D 1 A PEE 61-64 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[19 a.. pdb_complex 40 238 compound 8eqt 100.0 A 1 A AP3A_SARS2 E 1 B PEE 122:206 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[19 a.. pdb_complex 40 238 compound 8eqt 100.0 B 1 B AP3A_SARS2 D 1 A PEE 122:206 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[19 a.. pdb_complex 40 238 compound 8eqt 100.0 B 1 B AP3A_SARS2 E 1 B PEE 61-64 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[19 a.. pdb_complex 40 238 compound 8eqt 100.0 B 1 B AP3A_SARS2 F 1 B PEE 72:75:76:78:79:122:123 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[22 a.. pdb_complex 40 237 compound 8equ 100.0 A 1 A AP3A_SARS2 I 1 A PEE 75:78:79:123:127 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a.. pdb_complex 40 237 compound 8equ 100.0 A 1 A AP3A_SARS2 J 1 B PEE 61 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a.. pdb_complex 40 237 compound 8equ 100.0 B 1 B AP3A_SARS2 I 1 A PEE 61 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a.. pdb_complex 40 237 compound 8equ 100.0 B 1 B AP3A_SARS2 J 1 B PEE 75:78:79:123:127 ORF3a protein 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a.. pdb_complex 40 237 homo 8eqs 76.6 A 1 A AP3A_SARS B 1 B AP3A_SARS 46-48:50:51:53-55:57:58:61:62:65:66:82:85:88:89:105:108:112:115:116:119:122:144:160-162:164-166:168:170:173:185:187-189:215:216:218:222:223:225:230:232:234 ORF3a protein ORF3a protein[192 aa] pdb_complex 40 237 homo 8eqs 76.6 B 1 B AP3A_SARS A 1 A AP3A_SARS 46-48:50:51:53-55:57:58:61:62:65:66:82:85:88:89:105:108:112:115:116:119:122:144:160-162:164-166:168:170:173:185:187-189:215:216:218:222:223:225:230:232:234 ORF3a protein ORF3a protein[192 aa] pdb_complex 40 238 homo 6xdc 100.0 A 1 A AP3A_SARS2 B 1 B AP3A_SARS2 46:47:50:51:54:55:57-59:61:62:65:66:85:89:108:109:112:115:116:118:119:122:144:145:160:161:164:168:185:187-189:215:216:218:222:223:225:230:232:234 ORF3a protein ORF3a protein[193 aa] pdb_complex 40 238 homo 6xdc 100.0 B 1 B AP3A_SARS2 A 1 A AP3A_SARS2 46:47:50:51:54:55:57-59:61:62:65:66:85:88:89:108:109:112:115:116:118:119:122:144:145:160:161:164:168:185:187-189:215:216:218:222:223:225:230:232:234 ORF3a protein ORF3a protein[193 aa] pdb_complex 40 238 homo 7kjr 100.0 A 1 A AP3A_SARS2 B 1 B AP3A_SARS2 43:46-48:50:51:53-55:57-59:61:62:65:66:82:85:88:89:92:96:105:108:109:112:115:116:118:119:122:144:145:160-162:164:166:168:170:185:187-189:215:216:218:222-225:230:232:234 ORF3a protein ORF3a protein[193 aa] pdb_complex 40 238 homo 7kjr 100.0 B 1 B AP3A_SARS2 A 1 A AP3A_SARS2 43:46-48:50:51:53-55:57-59:61:62:65:66:82:85:88:89:92:96:105:108:109:112:115:116:118:119:122:144:145:160-162:164:166:168:170:185:187-189:215:216:218:222-225:228:230:232:234 ORF3a protein ORF3a protein[193 aa] pdb_complex 40 238 homo 8eqj 100.0 A 1 A AP3A_SARS2 B 1 B AP3A_SARS2 47:48:50:51:54:55:57:58:61:62:64-66:85:88:92:96:105:108:112:115:116:118:119:122:144:160-162:164-166:168:170:173:185:187-189:215:216:218:222:223:225:228:230:232 ORF3a protein ORF3a protein[192 aa] pdb_complex 40 238 homo 8eqj 100.0 B 1 B AP3A_SARS2 A 1 A AP3A_SARS2 47:48:50:51:54:55:57:58:61:62:64-66:85:88:92:96:105:108:112:115:116:118:119:122:144:160-162:164-166:168:170:173:185:187-189:215:216:218:222:223:225:228:230:232 ORF3a protein ORF3a protein[192 aa] pdb_complex 40 238 homo 8eqt 100.0 A 1 A AP3A_SARS2 B 1 B AP3A_SARS2 43:50:51:54:55:57-59:61:62:65:66:82:85:88:89:108:112:115:116:118:119:122:144:160-162:164-166:168:170:173:185:187-189:216:218:222:223:228:230:232 ORF3a protein ORF3a protein[191 aa] pdb_complex 40 238 homo 8eqt 100.0 B 1 B AP3A_SARS2 A 1 A AP3A_SARS2 43:50:51:54:55:57-59:61:62:65:66:82:85:88:89:108:112:115:116:118:119:122:144:160-162:164-166:168:170:173:185:187-189:216:218:222:223:228:230:232 ORF3a protein ORF3a protein[191 aa] pdb_complex 40 237 homo 8equ 100.0 A 1 A AP3A_SARS2 B 1 B AP3A_SARS2 47:50:51:53-55:57-59:61:62:65:66:82:85:88:89:96:108:112:115:116:119:122:144:145:160-162:164-166:168:170:173:185:187-189:215:216:218:223:225:228:230:232:234 ORF3a protein ORF3a protein[191 aa] pdb_complex 40 237 homo 8equ 100.0 B 1 B AP3A_SARS2 A 1 A AP3A_SARS2 47:50:51:53-55:57-59:61:62:64-66:82:85:88:89:96:108:112:115:116:119:122:144:145:160-162:164-166:168:170:173:185:187-189:215:216:218:223:225:228:230:232:234 ORF3a protein ORF3a protein[191 aa]