type start end name pdb_id identity asym_id_homo oper_homo auth_asym_id_homo mol_id_homo asym_id_con oper_con auth_asym_id_con mol_id_con sites description_homo description_con length 1 212 id 1 212 IL6_HUMAN title 1 212 RecName: Full=Interleukin-6 ; Short=IL-6;AltName: Full=B-cell stimulatory factor 2; Short=BSF-2;AltName: Full=CTL differentiation factor; Short=CDF;AltName: Full=Hybridoma growth factor;AltName: Full=Interferon beta-2; Short=IFN-beta-2;Flags: Precursor; seq 1 212 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM uniprot 1 29 SIGNAL ECO:0000269|PubMed:2610854, ECO:0000269|PubMed:3279116" uniprot 30 212 CHAIN /note="Interleukin-6" /id="PRO_0000015582" disorder 1 14 predicted_by_DISOPRED disorder 28 28 predicted_by_DISOPRED disorder 32 43 predicted_by_DISOPRED pdb_monomer 42 212 monomer 4cni 100.0 C C IL6_HUMAN 42-212 pdb_monomer 28 211 monomer 2l3y 40.7 A A IL6_MOUSE 28-38:40-44:46-211 pdb_complex 48 212 hetero 5fuc 99.3 A 1 A IL6_HUMAN F 1 V 48:50:51:54:103:106:108:210-212 INTERLEUKIN-6 VHH6[124 aa] pdb_complex 55 209 hetero 1i1r 26.5 B 1 B Q98823_HHV8 A 1 A IL6RB_HUMAN 55:56:59:62:138:141:142:145:149:152 VIRAL IL-6 INTERLEUKIN-6 RECEPTOR BETA CHAIN[301 aa] pdb_complex 55 209 hetero 1i1r 26.5 B 1 B Q98823_HHV8 A 2 A IL6RB_HUMAN 72-77:82-87:89:179:182:184-186:189 VIRAL IL-6 INTERLEUKIN-6 RECEPTOR BETA CHAIN[301 aa] pdb_complex 47 212 hetero 1p9m 100.0 B 1 B IL6_HUMAN A 1 A IL6RB_HUMAN 47:52:55:56:59:62:138:141:142:145:152:153 Interleukin-6 Interleukin-6 receptor beta chain[298 aa] pdb_complex 47 212 hetero 1p9m 100.0 B 1 B IL6_HUMAN A 2 A IL6RB_HUMAN 83-90:178:182:183:185:186:189 Interleukin-6 Interleukin-6 receptor beta chain[298 aa] pdb_complex 47 212 hetero 1p9m 100.0 B 1 B IL6_HUMAN C 1 C IL6RA_HUMAN 58:61:82:97:101-103:203:206-208:210:211 Interleukin-6 Interleukin-6 receptor alpha chain[201 aa] pdb_complex 48 212 hetero 5fuc 99.3 A 1 A IL6_HUMAN D 1 D D6R9R8_HUMAN:IL6RA_HUMAN 58:61:101-104:199:200:203:206-208:210:211 INTERLEUKIN-6 INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-.. pdb_complex 47 212 hetero 8qy5 100.0 B 1 B IL6_HUMAN C 1 C IL6RA_HUMAN 58:82:85:94:101-104:203:206:207:210:211 Interleukin-6 Interleukin-6 receptor subunit alpha[201 aa] pdb_complex 42 212 hetero 4cni 100.0 C 1 C IL6_HUMAN E 1 H 75:76:131:132:134:180-185:187:188 INTERLEUKIN-6 OLOKIZUMAB HEAVY CHAIN, FAB PORTION[219 aa] pdb_complex 42 212 hetero 4cni 100.0 C 1 C IL6_HUMAN F 1 L 85:181-183:185:186 INTERLEUKIN-6 OLOKIZUMAB LIGHT CHAIN, FAB PORTION[214 aa] pdb_complex 46 212 hetero 4j4l 99.4 C 1 C IL6_HUMAN A 1 A A4L9V2_LISMN:Q4G1L3_EPTBU 47:48:51:52:54-56:58:59:138:141:145:146:148:149:152:153:210 Interleukin-6 Internalin B,REPEAT MODULES,Variable lymphocyte re.. pdb_complex 47 212 hetero 4o9h 100.0 A 1 A IL6_HUMAN B 1 H 101-103:106:108:157:207:210-212 Interleukin-6 Heavy Chain of the Camelid Fab fragment 61H7[200 a.. pdb_complex 47 212 hetero 4o9h 100.0 A 1 A IL6_HUMAN C 1 L 49-51:54:55:58:210 Interleukin-6 Light Chain of the Camelid Fab fragment 61H7[211 a.. pdb_complex 51 212 hetero 4zs7 100.0 A 1 A IL6_HUMAN B 1 H 58:61:62:65:68:192:196:199:200:203:206:207:210 Interleukin-6 Llama Fab fragment 68F2 heavy chain[222 aa] pdb_complex 51 212 hetero 4zs7 100.0 A 1 A IL6_HUMAN C 1 L 95:97:102-104:200:203:204:207:210:211 Interleukin-6 Llama Fab fragment 68F2 light chain[210 aa] pdb_complex 49 212 hetero 5fuc 100.0 B 1 B IL6_HUMAN E 1 E 50:51:106:108:210-212 INTERLEUKIN-6 VHH6[110 aa] pdb_complex 44 212 hetero 8d82 100.0 B 1 D IL6_HUMAN A 1 C IL6RA_HUMAN 58:61:83:86:94:101-103:203:206-208:210:211 Interleukin-6 Soluble interleukin-6 receptor subunit alpha[296 a.. pdb_complex 44 212 hetero 8d82 100.0 B 1 D IL6_HUMAN C 1 A IL6RB_HUMAN 44:47:52:55:56:59:62:138:141:142:149:152:153 Interleukin-6 Interleukin-6 receptor subunit beta[589 aa] pdb_complex 44 212 hetero 8d82 100.0 B 1 D IL6_HUMAN F 1 E IL6RB_HUMAN 76:82-89:183:185:186:190 Interleukin-6 Interleukin-6 receptor subunit beta[589 aa] pdb_complex 47 212 hetero 8qy5 100.0 B 1 B IL6_HUMAN A 1 A IL6RB_MOUSE 52:55:59:62:138:141:142:145:149:152:153 Interleukin-6 Interleukin-6 receptor subunit beta[584 aa] pdb_complex 47 212 hetero 8qy5 100.0 B 1 B IL6_HUMAN F 1 D IL6RB_MOUSE 74:76:82-90:182:183:185:190 Interleukin-6 Interleukin-6 receptor subunit beta[584 aa] pdb_complex 44 212 nucleotide 4ni7 100.0 A 1 A IL6_HUMAN B 1 B 44:47:52:55:56:58:59:61:62:145:146:149:152:153:156:199:203:206:210 Interleukin-6 SOMAmer SL1025 pdb_complex 42 212 nucleotide 4ni9 100.0 B 1 A IL6_HUMAN A 1 B 42:44:47:52:55:56:58:59:61:62:142:145:146:149:152:153:156:199:203:206:207:210 Interleukin-6 SOMAmer SL1025 pdb_complex 42 212 nucleotide 4ni9 100.0 B 1 A IL6_HUMAN D 1 D 135-139 Interleukin-6 SOMAmer SL1025 pdb_complex 47 212 homo 1alu 100.0 A 1 A IL6_HUMAN A 2 A IL6_HUMAN 127:130:131:141:144:145:148:149:152:153:155:156:158:159:161-164:166:168-170 INTERLEUKIN-6 INTERLEUKIN-6[157 aa] pdb_complex 47 212 homo 1alu 100.0 A 1 A IL6_HUMAN A 3 A IL6_HUMAN 54:58:61:79:103:104:199:203:206:207:210 INTERLEUKIN-6 INTERLEUKIN-6[157 aa] pdb_complex 42 212 homo 4ni9 100.0 B 1 A IL6_HUMAN C 1 C IL6_HUMAN 138:141:145 Interleukin-6 Interleukin-6[148 aa] pdb_complex 47 212 precipitant 1alu 100.0 A 1 A IL6_HUMAN B 1 A SO4 102:103:207 INTERLEUKIN-6 SULFATE ION[5 atoms] pdb_complex 47 212 precipitant 1alu 100.0 A 1 A IL6_HUMAN B 3 A SO4 199:203 INTERLEUKIN-6 SULFATE ION[5 atoms] pdb_complex 47 212 precipitant 1alu 100.0 A 1 A IL6_HUMAN D 1 A SO4 183:184 INTERLEUKIN-6 SULFATE ION[5 atoms] pdb_complex 47 212 precipitant 1alu 100.0 A 1 A IL6_HUMAN E 1 A SO4 68:78:79:192:196 INTERLEUKIN-6 SULFATE ION[5 atoms] pdb_complex 42 212 precipitant 4cni 100.0 C 1 C IL6_HUMAN I 1 C SO4 46:47:52 INTERLEUKIN-6 SULFATE ION[5 atoms] pdb_complex 47 212 precipitant 1alu 100.0 A 1 A IL6_HUMAN F 1 A TLA 203:206:207:210 INTERLEUKIN-6 L(+)-TARTARIC ACID[10 atoms]