type start end name pdb_id identity asym_id_homo oper_homo auth_asym_id_homo mol_id_homo asym_id_con oper_con auth_asym_id_con mol_id_con sites description_homo description_con length 1 515 id 1 515 INAR2_HUMAN title 1 515 RecName: Full=Interferon alpha/beta receptor 2; Short=IFN-R-2; Short=IFN-alpha binding protein; Short=IFN-alpha/beta receptor 2;AltName: Full=Interferon alpha binding protein;AltName: Full=Type I interferon receptor 2;Flags: Precursor; seq 1 515 MLLSQNAFIFRSLNLVLMVYISLVFGISYDSPDYTDESCTFKISLRNFRSILSWELKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRSTHEAYVTVLEGFSGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINVMVKFPSIVEEELQFDLSLVIEEQSEGIVKKHKPEIKGNMSGNFTYIIDKLIPNTNYCVSVYLEHSDEQAVIKSPLKCTLLPPGQESESAESAKIGGIITVFLIALVLTSTIVTLKWIGYICLRNSLPKVLNFHNFLAWPFPNLPPLEAMDMVEVIYINRKKKVWDYNYDDESDSDTEAAPRTSGGGYTMHGLTVRPLGQASATSTESQLIDPESEEEPDLPEVDVELPTMPKDSPQQLELLSGPCERRKSPLQDPFPEEDYSSTEGSGGRITFNVDLNSVFLRVLDDEDSDDLEAPLMLSSHLEEMVDPEDPDNVQSNHLLASGEGTQPTFPSPSSEGLWSEDAPSDQSDTSESDVDLGDGYIMR uniprot 1 26 SIGNAL uniprot 27 515 CHAIN /note="Interferon alpha/beta receptor 2" /id="PRO_0000011006" uniprot 27 243 TOPO_DOM /note="Extracellular" uniprot 244 264 TRANSMEM /note="Helical" uniprot 265 515 TOPO_DOM /note="Cytoplasmic" uniprot 318 418 REGION /note="Disordered" uniprot 418 444 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" uniprot 455 515 REGION /note="Disordered" uniprot 466 497 COMPBIAS /note="Polar residues" disorder 1 18 predicted_by_DISOPRED disorder 324 330 predicted_by_DISOPRED disorder 349 381 predicted_by_DISOPRED disorder 383 383 predicted_by_DISOPRED disorder 387 387 predicted_by_DISOPRED disorder 400 401 predicted_by_DISOPRED disorder 404 416 predicted_by_DISOPRED disorder 450 450 predicted_by_DISOPRED disorder 477 515 predicted_by_DISOPRED pdb_monomer 28 237 monomer 2lag 100.0 A B INAR2_HUMAN 28-237 pdb_monomer 28 237 monomer 2hym 100.0 A A Q15467_HUMAN 28-237 pdb_monomer 28 237 monomer 1n6v 100.0 A A INAR2_HUMAN 28-237 pdb_monomer 28 237 monomer 1n6u 100.0 A A INAR2_HUMAN 28-237 pdb_monomer 38 233 monomer 2kz1 100.0 B B Q15467_HUMAN 38-233 pdb_monomer 36 232 monomer 3se4 100.0 C C INAR2_HUMAN 36-232 pdb_monomer 38 232 monomer 3s9d 100.0 D D INAR2_HUMAN 38-232 pdb_monomer 38 231 monomer 3se3 100.0 C C INAR2_HUMAN 38-231 pdb_monomer 39 231 monomer 3s9d 100.0 B B INAR2_HUMAN 39-231 pdb_monomer 133 232 monomer 3s8w 100.0 C C INAR2_HUMAN 133-232 pdb_monomer 134 232 monomer 3s8w 100.0 B B INAR2_HUMAN 134-232 pdb_monomer 133 232 monomer 3s8w 100.0 A A INAR2_HUMAN 133-232 pdb_complex 28 237 hetero 2hym 100.0 A 1 A Q15467_HUMAN B 1 B IFNA2_HUMAN 73-78:103-105:107:123:124:127:165-167:186:213:214 Soluble IFN alpha/beta receptor Interferon alpha-2[165 aa] pdb_complex 38 233 hetero 2kz1 100.0 B 1 B Q15467_HUMAN A 1 A IFNA2_HUMAN 71:73-77:79:97:100:101:103:104:107-109:123-125:127:159-163:165-167:186:214-216 Soluble IFN alpha/beta receptor Interferon alpha-2[165 aa] pdb_complex 28 237 hetero 2lag 100.0 A 1 B INAR2_HUMAN B 1 A IFNA2_HUMAN 71-77:79:101:103:104:107-109:123-125:127:129:130:160-163:165-167:186:213-216:218 Interferon alpha/beta receptor 2 Interferon alpha-2[165 aa] pdb_complex 39 231 hetero 3s9d 100.0 B 1 B INAR2_HUMAN A 1 A IFNA2_HUMAN 71-77:79:103:104:107:109:123:125:127:129:130:214:218 Interferon alpha/beta receptor 2 Interferon alpha-2[127 aa] pdb_complex 38 231 hetero 3se3 100.0 C 1 C INAR2_HUMAN B 1 B Q86UP4_HUMAN 71-77:103:104:107:123:125:127:130 Interferon alpha/beta receptor 2 Interferon alpha 2b[128 aa] pdb_complex 38 232 hetero 3s9d 100.0 D 1 D INAR2_HUMAN C 1 C IFNA2_HUMAN 71-77:103:104:107:109:123:125:127:129:130:214:215:218 Interferon alpha/beta receptor 2 Interferon alpha-2[116 aa] pdb_complex 36 232 hetero 3se4 100.0 C 1 C INAR2_HUMAN B 1 B IFNW1_HUMAN 71-77:103:107:109:123:125:127:129:130:214:217:218 Interferon alpha/beta receptor 2 Interferon omega-1[143 aa] pdb_complex 133 232 metal 3s8w 100.0 A 1 A INAR2_HUMAN D 1 A CL 199 Interferon alpha/beta receptor 2 CHLORIDE ION[1 atoms] pdb_complex 133 232 metal 3s8w 100.0 C 1 C INAR2_HUMAN E 1 C CL 182:183:195 Interferon alpha/beta receptor 2 CHLORIDE ION[1 atoms] pdb_complex 38 232 metal 3s9d 100.0 D 1 D INAR2_HUMAN E 1 D CL 105:125-127 Interferon alpha/beta receptor 2 CHLORIDE ION[1 atoms]