type start end name pdb_id identity asym_id_homo oper_homo auth_asym_id_homo mol_id_homo asym_id_con oper_con auth_asym_id_con mol_id_con sites description_homo description_con length 1 165 id 1 165 ISG15_HUMAN title 1 165 RecName: Full=Ubiquitin-like protein ISG15;AltName: Full=Interferon-induced 15 kDa protein;AltName: Full=Interferon-induced 17 kDa protein; Short=IP17;AltName: Full=Ubiquitin cross-reactive protein; Short=hUCRP;Flags: Precursor; seq 1 165 MGWDLTVKMLAGNEFQVSLSSSMSVSELKAQITQKIGVHAFQQRLAVHPSGVALQDRVPLASQGLGPGSTVLLVVDKCDEPLSILVRNNKGRSSTYEVRLTQTVAHLKQQVSGLEGVQDDLFWLTFEGKPLEDQLPLGEYGLKPLSTVFMNLRLRGGGTEPGGRS uniprot 2 157 CHAIN /note="Ubiquitin-like protein ISG15" /id="PRO_0000035986" uniprot 158 165 PROPEP /note="Removed in mature form" /id="PRO_0000035987" uniprot 2 78 DOMAIN /note="Ubiquitin-like 1" uniprot 79 157 DOMAIN /note="Ubiquitin-like 2" uniprot 153 157 REGION /note="Involved in the ligation of specific target proteins" disorder 1 1 predicted_by_DISOPRED disorder 157 165 predicted_by_DISOPRED pdb_monomer 2 157 monomer 7rbs 100.0 B B ISG15_HUMAN 2-157 pdb_complex 80 156 hetero 3phx 100.0 B 1 B ISG15_HUMAN A 1 A L_CCHFI 89-91:108:120:122:123:125:128:130-133:149:151:153-156 Ubiquitin-like protein ISG15 RNA-directed RNA polymerase L[162 aa] pdb_complex 80 156 hetero 3phx 100.0 B 2 B ISG15_HUMAN A 1 A L_CCHFI 127:143 Ubiquitin-like protein ISG15 RNA-directed RNA polymerase L[162 aa] pdb_complex 4 156 hetero 3pse 98.7 B 1 B ISG15_HUMAN A 1 A Q6TQF5_9VIRU 89-91:108:119:120:122:123:125:128:151:153-156 Ubiquitin-like protein ISG15 RNA polymerase[164 aa] pdb_complex 80 156 hetero 5w8t 100.0 A 1 B ISG15_HUMAN B 1 A K0BWD0_9BETC 85:123:125:127-130:132-134:143:144:152-156 Ubiquitin-like protein ISG15 ORF1ab[319 aa] pdb_complex 4 156 hetero 6bi8 99.3 C 1 C ISG15_HUMAN A 1 A K4LC41_9BETC 34:123:125:127-130:132:134:143-145:152-156 Ubiquitin-like protein ISG15 ORF1a[259 aa] pdb_complex 4 154 hetero 3r66 100.0 C 1 C ISG15_HUMAN A 1 A NS1_INBLE 8-12:46:48:49:72-74 Ubiquitin-like protein ISG15 Non-structural protein 1[96 aa] pdb_complex 3 155 hetero 3rt3 99.3 A 1 B ISG15_HUMAN B 1 C NS1_INBLE 9:11:36:74-78 Ubiquitin-like protein ISG15 Non-structural protein 1[94 aa] pdb_complex 80 156 hetero 5tl6 100.0 C 1 C ISG15_HUMAN B 1 D R1AB_CVHSA 87:123:129:144:145:149:151-156 Ubiquitin-like protein ISG15 Replicase polyprotein 1ab[312 aa] pdb_complex 79 154 hetero 6ffa 100.0 B 1 B ISG15_HUMAN A 1 A POLG_FMDVO 87:121:123:125:128:149:152-154 Ubiquitin-like protein ISG15 Lbpro[156 aa] pdb_complex 79 156 hetero 6xa9 100.0 B 1 B ISG15_HUMAN A 1 A R1AB_SARS2 123:127-130:151-156 ISG15 CTD-propargylamide Non-structural protein 3[313 aa] pdb_complex 2 157 hetero 7rbs 100.0 B 1 B ISG15_HUMAN A 1 A R1A_SARS2 2:18:20-23:27:57:90:121:123:127-130:151-157 Ubiquitin-like protein ISG15 Papain-like protease[312 aa] pdb_complex 79 157 hetero 8oif 100.0 B 1 I ISG15_HUMAN A 1 A UBA7_HUMAN 89:92:118:120:121:123:125:128:130:149:151-157 Ubiquitin-like protein ISG15 Ubiquitin-like modifier-activating enzyme 7[704 aa.. pdb_complex 78 157 hetero 8se9 100.0 B 1 B ISG15_HUMAN A 1 A UBA7_HUMAN 87-90:92-94:114:115:118:120:121:123:125:127:128:130:132:149:151-157 Ubiquitin-like protein ISG15 Ubiquitin-like modifier-activating enzyme 7[989 aa.. pdb_complex 82 157 hetero 8se9 100.0 D 1 D ISG15_HUMAN C 1 C UB2L6_HUMAN 152:156:157 Ubiquitin-like protein ISG15 Ubiquitin/ISG15-conjugating enzyme E2 L6[152 aa] pdb_complex 3 155 compound 3rt3 99.3 A 1 B ISG15_HUMAN C 1 B SIN 130:153 Ubiquitin-like protein ISG15 SUCCINIC ACID[8 atoms] pdb_complex 3 155 compound 3rt3 99.3 A 1 B ISG15_HUMAN D 1 B SIN 29:40:41:56:138:139:141 Ubiquitin-like protein ISG15 SUCCINIC ACID[8 atoms] pdb_complex 79 157 compound 8oif 100.0 B 1 I ISG15_HUMAN D 1 I AMP 157 Ubiquitin-like protein ISG15 ADENOSINE MONOPHOSPHATE[23 atoms] pdb_complex 3 154 metal 1z2m 99.3 A 1 A UCRP_HUMAN B 1 A OS4 9:12:13 interferon, alpha-inducible protein (clone IFI-15K.. OSMIUM 4+ ION[1 atoms] pdb_complex 80 156 metal 3phx 100.0 B 2 B ISG15_HUMAN H 1 A ZN 127 Ubiquitin-like protein ISG15 ZINC ION[1 atoms] pdb_complex 80 156 metal 3phx 100.0 B 1 B ISG15_HUMAN N 1 B ZN 106 Ubiquitin-like protein ISG15 ZINC ION[1 atoms] pdb_complex 80 156 metal 3phx 100.0 B 1 B ISG15_HUMAN P 1 B ZN 119 Ubiquitin-like protein ISG15 ZINC ION[1 atoms] pdb_complex 4 156 precipitant 3pse 98.7 B 1 B ISG15_HUMAN C 1 B 4LJ 156 Ubiquitin-like protein ISG15 1.7.6 3-bromanylpropan-1-amine[4 atoms] pdb_complex 80 156 precipitant 5w8t 100.0 A 1 B ISG15_HUMAN E 1 B AYE 156 Ubiquitin-like protein ISG15 prop-2-en-1-amine[4 atoms] pdb_complex 4 156 precipitant 6bi8 99.3 C 1 C ISG15_HUMAN I 1 A AYE 156 Ubiquitin-like protein ISG15 prop-2-en-1-amine[4 atoms] pdb_complex 4 156 precipitant 6bi8 99.3 C 1 C ISG15_HUMAN T 1 C PGE 121:152:153:155 Ubiquitin-like protein ISG15 TRIETHYLENE GLYCOL[10 atoms] pdb_complex 80 156 precipitant 3phx 100.0 B 1 B ISG15_HUMAN M 1 B NEH 156 Ubiquitin-like protein ISG15 ETHANAMINE[3 atoms] pdb_complex 80 156 precipitant 3phx 100.0 B 1 B ISG15_HUMAN Q 1 B ACY 119 Ubiquitin-like protein ISG15 ACETIC ACID[4 atoms] pdb_complex 4 156 precipitant 3pse 98.7 B 1 B ISG15_HUMAN D 1 B GOL 87-89:91:149-151 Ubiquitin-like protein ISG15 GLYCEROL[6 atoms] pdb_complex 4 156 precipitant 6bi8 99.3 C 1 C ISG15_HUMAN G 1 A GOL 149 Ubiquitin-like protein ISG15 GLYCEROL[6 atoms] pdb_complex 4 156 precipitant 6bi8 99.3 C 1 C ISG15_HUMAN H 1 A GOL 130 Ubiquitin-like protein ISG15 GLYCEROL[6 atoms] pdb_complex 4 156 precipitant 6bi8 99.3 D 1 D ISG15_HUMAN O 1 B GOL 127:129 Ubiquitin-like protein ISG15 GLYCEROL[6 atoms] pdb_complex 79 154 precipitant 6ffa 100.0 B 1 B ISG15_HUMAN J 1 B GOL 108:120:122:123:153 Ubiquitin-like protein ISG15 GLYCEROL[6 atoms] pdb_complex 80 156 precipitant 5w8t 100.0 A 1 B ISG15_HUMAN K 1 A MPD 127:149 Ubiquitin-like protein ISG15 (4S)-2-METHYL-2,4-PENTANEDIOL[8 atoms] pdb_complex 80 156 precipitant 5w8t 100.0 C 1 D ISG15_HUMAN O 1 D MPD 120:121:153:155 Ubiquitin-like protein ISG15 (4S)-2-METHYL-2,4-PENTANEDIOL[8 atoms]