type start end name pdb_id identity asym_id_homo oper_homo auth_asym_id_homo mol_id_homo asym_id_con oper_con auth_asym_id_con mol_id_con sites description_homo description_con length 1 358 id 1 358 HLAE_HUMAN title 1 358 RecName: Full=HLA class I histocompatibility antigen, alpha chain E;AltName: Full=MHC class I antigen E;Contains: RecName: Full=Soluble HLA class I histocompatibility antigen, alpha chain E; Short=sHLA-E ;Flags: Precursor; seq 1 358 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSESHSL uniprot 1 21 SIGNAL uniprot 22 358 CHAIN /note="HLA class I histocompatibility antigen, alpha chain E" /id="PRO_0000018882" uniprot 22 0 CHAIN /note="Soluble HLA class I histocompatibility antigen, alpha chain E" /id="PRO_0000445757" uniprot 22 305 TOPO_DOM /note="Extracellular" uniprot 306 329 TRANSMEM /note="Helical" uniprot 330 358 TOPO_DOM /note="Cytoplasmic" uniprot 206 294 DOMAIN /note="Ig-like C1-type" uniprot 22 111 REGION /note="Alpha-1" uniprot 112 203 REGION /note="Alpha-2" uniprot 204 295 REGION /note="Alpha-3" uniprot 296 305 REGION /note="Connecting peptide" uniprot 333 358 REGION /note="Disordered" uniprot 344 358 COMPBIAS /note="Polar residues" uniprot 28 28 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0000269|PubMed:35705051, ECO:0007744|PDB:7P4B" uniprot 84 84 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0007744|PDB:7P49, ECO:0007744|PDB:7P4B" uniprot 87 87 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0007744|PDB:7P4B" uniprot 98 98 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0007744|PDB:7P49, ECO:0007744|PDB:7P4B" uniprot 98 98 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen" uniprot 105 105 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0007744|PDB:7P49, ECO:0007744|PDB:7P4B" uniprot 105 105 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen" uniprot 164 164 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0000269|PubMed:35705051, ECO:0007744|PDB:7P49, ECO:0007744|PDB:7P4B" uniprot 164 164 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen" uniprot 167 167 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0000269|PubMed:35705051, ECO:0007744|PDB:7P49, ECO:0007744|PDB:7P4B" uniprot 167 167 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen" uniprot 177 177 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen" uniprot 180 180 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0000269|PubMed:35705051, ECO:0007744|PDB:7P49, ECO:0007744|PDB:7P4B" uniprot 180 180 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen" uniprot 192 192 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0000269|PubMed:35705051, ECO:0007744|PDB:7P49" uniprot 192 192 BINDING /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen" disorder 1 18 predicted_by_DISOPRED disorder 200 208 predicted_by_DISOPRED disorder 332 358 predicted_by_DISOPRED pdb_monomer 22 297 monomer 7p4b 100.0 C C HLAE_HUMAN 22-297 pdb_complex 22 295 hetero 6ggm 100.0 A 1 A E2G051_HUMAN B 1 B B2MG_HUMAN 27:29-31:33:46:48:53:56:69:114:117-119:136-138:140-143:213:223:225:252:253:255-259:263:265 MHC class I antigen Beta-2-microglobulin[100 aa] pdb_complex 22 297 hetero 7bh8 100.0 A 1 A HLAE_HUMAN D 1 D B2MG_HUMAN 248 HLA class I histocompatibility antigen, alpha chai.. Beta-2-microglobulin[98 aa] pdb_complex 22 295 hetero 6ggm 100.0 A 1 A E2G051_HUMAN E 1 P 26:28:30:45:66:80:83:84:87:88:91:94:95:98:101:102:105:118:120:135:137:145:164:167:173:176:177:180:188:192 MHC class I antigen Mtb44*P2-Phe peptide variant (ARG-PHE-PRO-ALA-LYS-.. pdb_complex 22 295 hetero 6gh1 100.0 A 1 A E2G051_HUMAN C 1 P INHA_MYCTU 28:30:66:83:84:88:94:98:101:105:116:118:120:137:164:167:173:177:180:184:188:192 MHC class I antigen Enoyl-[acyl-carrier-protein] reductase [NADH][9 aa.. pdb_complex 22 295 hetero 6gh4 100.0 A 1 A E2G051_HUMAN I 1 P 28:30:66:83:84:87:88:91:94:95:98:101:105:116:118:120:135:137:164:167:173:177:180:184:188:192 MHC class I antigen ARG-GLN-PRO-ALA-LYS-ALA-PRO-LEU-LEU[9 aa] pdb_complex 22 295 hetero 6ghn 100.0 A 1 A Q59EE1_HUMAN E 1 P 28:30:66:84:87:88:94:95:98:102:105:118:120:137:144:145:164:167:173:180:184:188:192 HLA class I histocompatibility antigen, E alpha ch.. ARG-LEU-PRO-ALA-LYS-ALA-PRO-LEU-PHE[9 aa] pdb_complex 22 295 hetero 6gl1 100.0 A 1 A E2G051_HUMAN I 1 P 28:30:66:83:84:87:88:90:91:94:98:101:102:105:116:118:120:137:164:167:173:176:177:180:184:188:192 MHC class I antigen ARG-MET-TYR-SER-PRO-THR-SER-ILE-LEU[9 aa] pdb_complex 23 297 hetero 6zkw 100.0 A 1 A HLAE_HUMAN D 1 D 90:94:170:171:173:175:176 HLA class I histocompatibility antigen, alpha chai.. T-cell receptor alpha chain[188 aa] pdb_complex 23 297 hetero 6zkw 100.0 A 1 A HLAE_HUMAN E 1 E 90:93:94:96:97:100:170:171:173 HLA class I histocompatibility antigen, alpha chai.. T-cell receptor beta chain[243 aa] pdb_complex 22 297 hetero 7bh8 100.0 A 1 A HLAE_HUMAN E 1 G 78:79:82-84:86:90:176:179:184:188 HLA class I histocompatibility antigen, alpha chai.. 3H4 Fab heavy chain[225 aa] pdb_complex 22 297 hetero 7bh8 100.0 A 1 A HLAE_HUMAN F 1 H 79:83:187:188:191 HLA class I histocompatibility antigen, alpha chai.. 3H4 Fab light chain[214 aa] pdb_complex 22 297 hetero 7bh8 100.0 A 1 A HLAE_HUMAN I 1 P 28:30:66:80:83:84:87:88:91:94:95:98:101:102:105:116:118:120:137:154:164:167:173:176:177:180:184:188:192 HLA class I histocompatibility antigen, alpha chai.. VL9 leader peptide[9 aa] pdb_complex 22 297 hetero 7ndq 100.0 A 1 AAA HLAE_HUMAN C 1 CCC B6S6I4_9HIV1 28:30:80:83:84:87:88:90:91:94:98:101:105:118:135:145:164:167:168:171:176:177:180:188:192 HLA class I histocompatibility antigen, alpha chai.. Gag6V[9 aa] pdb_complex 22 297 hetero 7ndq 100.0 A 1 AAA HLAE_HUMAN D 1 DDD TVA4_HUMAN:A0A075B6U7_HUMAN:TRAR1_HUMAN 171:173-176:178:179:183:184 HLA class I histocompatibility antigen, alpha chai.. TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha.. pdb_complex 22 297 hetero 7ndq 100.0 A 1 AAA HLAE_HUMAN E 1 EEE TVB79_HUMAN:TJB12_HUMAN:K7N5M4_HUMAN 86:89:90:93:94:96:100:176 HLA class I histocompatibility antigen, alpha chai.. T cell receptor beta variable 7-9,M1-specific T ce.. pdb_complex 22 297 hetero 7p49 100.0 A 1 A HLAE_HUMAN I 1 P PPSB_MYCTU 28:30:45:66:83:84:87:88:91:94:98:101:105:135:137:145:154:164:167:168:173:177:180:184:188:192 HLA class I histocompatibility antigen, alpha chai.. Phenolphthiocerol/phthiocerol polyketide synthase .. pdb_complex 22 296 hetero 7p4b 100.0 A 1 A HLAE_HUMAN I 1 P ESXH_MYCTU 28:30:66:80:83:84:87:91:94:98:101:105:118:164:167:173:176:177:180:184:188:192 HLA class I histocompatibility antigen, alpha chai.. ESAT-6-like protein EsxH[9 aa] pdb_complex 22 292 hetero 8qfy 100.0 A 1 AAA HLAE_HUMAN D 1 DDD 83:86:170-172:175:176:179:183:187 HLA class I histocompatibility antigen, alpha chai.. T-cell receptor alpha chain[187 aa] pdb_complex 22 295 metal 6ggm 100.0 A 1 A E2G051_HUMAN G 1 A ZN 202:204 MHC class I antigen ZINC ION[1 atoms] pdb_complex 22 295 metal 6ggm 100.0 A 1 A E2G051_HUMAN H 1 A ZN 173:176 MHC class I antigen ZINC ION[1 atoms] pdb_complex 22 295 metal 6ggm 100.0 A 1 A E2G051_HUMAN I 1 A ZN 217:218 MHC class I antigen ZINC ION[1 atoms] pdb_complex 22 297 homo 7bh8 100.0 A 1 A HLAE_HUMAN C 1 C HLAE_HUMAN 218:219:240:245:247:248:271:274:277:278 HLA class I histocompatibility antigen, alpha chai.. HLA class I histocompatibility antigen, alpha chai.. pdb_complex 22 295 homo 7bh8 100.0 C 1 C HLAE_HUMAN A 1 A HLAE_HUMAN 106-109:111:140 HLA class I histocompatibility antigen, alpha chai.. HLA class I histocompatibility antigen, alpha chai.. pdb_complex 22 295 precipitant 6ggm 100.0 A 1 A E2G051_HUMAN J 1 A SO4 83:187:188 MHC class I antigen SULFATE ION[5 atoms] pdb_complex 22 295 precipitant 6ggm 100.0 A 1 A E2G051_HUMAN K 1 A SO4 96:100:103 MHC class I antigen SULFATE ION[5 atoms] pdb_complex 22 295 precipitant 6ggm 100.0 C 1 C E2G051_HUMAN P 1 D SO4 42 MHC class I antigen SULFATE ION[5 atoms] pdb_complex 22 295 precipitant 6gh1 100.0 D 1 C E2G051_HUMAN Q 1 C SO4 63:65:89 MHC class I antigen SULFATE ION[5 atoms] pdb_complex 22 295 precipitant 6ghn 100.0 C 1 C Q59EE1_HUMAN H 1 C SO4 158:159 HLA class I histocompatibility antigen, E alpha ch.. SULFATE ION[5 atoms] pdb_complex 22 295 precipitant 6gl1 100.0 A 1 A E2G051_HUMAN M 1 A SO4 240:246 MHC class I antigen SULFATE ION[5 atoms] pdb_complex 22 297 precipitant 7p49 100.0 A 1 A HLAE_HUMAN O 1 A SO4 235:237:239 HLA class I histocompatibility antigen, alpha chai.. SULFATE ION[5 atoms] pdb_complex 22 297 precipitant 7p49 100.0 A 1 A HLAE_HUMAN R 1 A SO4 129 HLA class I histocompatibility antigen, alpha chai.. SULFATE ION[5 atoms] pdb_complex 22 297 precipitant 7p49 100.0 A 1 A HLAE_HUMAN S 1 A SO4 253:254:264 HLA class I histocompatibility antigen, alpha chai.. SULFATE ION[5 atoms] pdb_complex 22 296 precipitant 7p49 100.0 C 1 C HLAE_HUMAN DA 1 C SO4 152 HLA class I histocompatibility antigen, alpha chai.. SULFATE ION[5 atoms] pdb_complex 22 296 precipitant 7p4b 100.0 A 1 A HLAE_HUMAN N 1 A SO4 108:109 HLA class I histocompatibility antigen, alpha chai.. SULFATE ION[5 atoms] pdb_complex 22 297 precipitant 7bh8 100.0 A 1 A HLAE_HUMAN K 1 A GOL 29:48:50:51 HLA class I histocompatibility antigen, alpha chai.. GLYCEROL[6 atoms] pdb_complex 22 297 precipitant 7bh8 100.0 A 1 A HLAE_HUMAN L 1 A GOL 52:199:230:260 HLA class I histocompatibility antigen, alpha chai.. GLYCEROL[6 atoms] pdb_complex 22 297 precipitant 7bh8 100.0 A 1 A HLAE_HUMAN M 1 A GOL 27:123:132:134:136 HLA class I histocompatibility antigen, alpha chai.. GLYCEROL[6 atoms] pdb_complex 22 297 precipitant 7bh8 100.0 A 1 A HLAE_HUMAN N 1 B GOL 225:227:255:263 HLA class I histocompatibility antigen, alpha chai.. GLYCEROL[6 atoms] pdb_complex 22 297 precipitant 7p49 100.0 A 1 A HLAE_HUMAN N 1 A GOL 96:100 HLA class I histocompatibility antigen, alpha chai.. GLYCEROL[6 atoms] pdb_complex 22 296 precipitant 7p49 100.0 C 1 C HLAE_HUMAN EA 1 D GOL 207:227:228 HLA class I histocompatibility antigen, alpha chai.. GLYCEROL[6 atoms] pdb_complex 22 296 precipitant 7p49 100.0 C 1 C HLAE_HUMAN Z 1 C GOL 232:254-256:262 HLA class I histocompatibility antigen, alpha chai.. GLYCEROL[6 atoms] pdb_complex 22 295 precipitant 7p49 100.0 E 1 E HLAE_HUMAN IA 1 E GOL 69 HLA class I histocompatibility antigen, alpha chai.. GLYCEROL[6 atoms] pdb_complex 22 297 precipitant 8qfy 100.0 F 1 FFF HLAE_HUMAN K 1 FFF ACT 60 HLA class I histocompatibility antigen, alpha chai.. ACETATE ION[4 atoms]