type start end name pdb_id identity asym_id_homo oper_homo auth_asym_id_homo mol_id_homo asym_id_con oper_con auth_asym_id_con mol_id_con sites description_homo description_con length 1 1170 id 1 1170 ITAL_HUMAN title 1 1170 RecName: Full=Integrin alpha-L ;AltName: Full=CD11 antigen-like family member A;AltName: Full=Leukocyte adhesion glycoprotein LFA-1 alpha chain; Short=LFA-1A;AltName: Full=Leukocyte function-associated molecule 1 alpha chain;AltName: CD_antigen=CD11a;Flags: Precursor; seq 1 1170 MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGAPGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNTYLSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPVVFRQEILVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDSEQLASGQEAGDPGCLKPLHEKDSESGGGKD uniprot 1 25 SIGNAL uniprot 26 1170 CHAIN /note="Integrin alpha-L" /id="PRO_0000016292" uniprot 26 1090 TOPO_DOM /note="Extracellular" uniprot 1091 1111 TRANSMEM /note="Helical" uniprot 1112 1170 TOPO_DOM /note="Cytoplasmic" uniprot 156 327 DOMAIN /note="VWFA" uniprot 1128 1170 REGION /note="Disordered" uniprot 1154 1170 COMPBIAS /note="Basic and acidic residues" uniprot 468 468 BINDING /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" /ligand_label="1" uniprot 470 470 BINDING /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" /ligand_label="1" uniprot 472 472 BINDING /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" /ligand_label="1" uniprot 476 476 BINDING /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" /ligand_label="1" uniprot 530 530 BINDING /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" /ligand_label="2" uniprot 532 532 BINDING /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" /ligand_label="2" uniprot 534 534 BINDING /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" /ligand_label="2" uniprot 538 538 BINDING /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" /ligand_label="2" uniprot 590 590 BINDING /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" /ligand_label="3" uniprot 594 594 BINDING /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" /ligand_label="3" uniprot 598 598 BINDING /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" /ligand_label="3" disorder 1 24 predicted_by_DISOPRED disorder 140 143 predicted_by_DISOPRED disorder 147 147 predicted_by_DISOPRED disorder 738 746 predicted_by_DISOPRED disorder 841 848 predicted_by_DISOPRED disorder 988 988 predicted_by_DISOPRED disorder 990 990 predicted_by_DISOPRED disorder 992 1014 predicted_by_DISOPRED disorder 1125 1170 predicted_by_DISOPRED pdb_monomer 26 616 monomer 5e6u 99.8 A A ITAL_HUMAN 26-616 pdb_monomer 26 615 monomer 5e6r 99.8 A A ITAL_HUMAN 26-615 pdb_monomer 26 615 monomer 5e6s 99.8 E E ITAL_HUMAN 26-615 pdb_monomer 26 614 monomer 5e6s 99.8 A A ITAL_HUMAN 26-614 pdb_monomer 26 615 monomer 5e6s 99.8 C C ITAL_HUMAN 26-615 pdb_monomer 26 1072 monomer 3k71 37.7 G G ITAX_HUMAN 26-42:45-132:138-384:386-407:409-437:440-507:510-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 1072 monomer 3k6s 37.7 A A ITAX_HUMAN 26-42:45-132:138-384:386-407:409-437:440-507:510-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 1072 monomer 5es4 37.7 A A ITAX_HUMAN 26-42:45-132:138-384:386-407:409-437:440-507:510-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 1072 monomer 4neh 37.6 A A ITAX_HUMAN 26-42:45-132:138-384:386-407:409-437:440-507:510-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 1072 monomer 4nen 37.6 A A ITAX_HUMAN 26-42:45-132:138-384:386-407:409-437:440-507:510-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 740 monomer 7p2d 39.8 A A ITAM_HUMAN 26-37:40-378:380-411:413-437:440-507:510-641:643-734:738-740 pdb_monomer 146 333 monomer 7kc3 98.9 A C ITAL_HUMAN 146-333 pdb_monomer 153 336 monomer 1rd4 100.0 D D ITAL_HUMAN 153-336 pdb_monomer 153 336 monomer 1rd4 100.0 B B ITAL_HUMAN 153-336 pdb_monomer 153 336 monomer 1rd4 100.0 A A ITAL_HUMAN 153-336 pdb_monomer 153 336 monomer 1rd4 100.0 C C ITAL_HUMAN 153-336 pdb_monomer 152 336 monomer 1dgq 99.5 A A ITAL_HUMAN 152-336 pdb_monomer 153 335 monomer 1zop 100.0 B B ITAL_HUMAN 153-335 pdb_monomer 153 335 monomer 1zop 100.0 A A ITAL_HUMAN 153-335 pdb_monomer 153 335 monomer 1zoo 100.0 B B ITAL_HUMAN 153-335 pdb_monomer 153 335 monomer 1zoo 100.0 A A ITAL_HUMAN 153-335 pdb_monomer 153 335 monomer 1lfa 100.0 A A ITAL_HUMAN 153-335 pdb_monomer 153 334 monomer 7kc5 100.0 B C ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 7kc5 100.0 A A ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 1lfa 100.0 B B ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 7kc6 100.0 B A ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 7kc6 100.0 A C ITAL_HUMAN 153-334 pdb_monomer 153 333 monomer 1zon 100.0 A A ITAL_HUMAN 153-333 pdb_monomer 153 334 monomer 3bqn 99.5 B C ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 3bqn 99.5 A B ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 3bqm 99.5 B C ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 3bqm 99.5 A B ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 1cqp 99.5 B B ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 1cqp 99.5 A A ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 3e2m 99.5 B B ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 3e2m 99.5 A A ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 4ixd 99.5 A A ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 1xdg 99.5 B B ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 1xdg 99.5 A A ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 1xdd 99.5 B B ITAL_HUMAN 153-334 pdb_monomer 153 334 monomer 1xdd 99.5 A A ITAL_HUMAN 153-334 pdb_monomer 153 333 monomer 1xuo 99.4 A A ITAL_HUMAN 153-333 pdb_monomer 154 332 monomer 3m6f 100.0 A A ITAL_HUMAN 154-332 pdb_monomer 154 332 monomer 2o7n 100.0 A A ITAL_HUMAN 154-332 pdb_monomer 153 332 monomer 3f78 99.4 C C ITAL_HUMAN 153-332 pdb_monomer 153 332 monomer 3f78 99.4 B B ITAL_HUMAN 153-332 pdb_monomer 153 332 monomer 3f74 99.4 A A ITAL_HUMAN 153-332 pdb_monomer 153 332 monomer 3f78 99.4 A A ITAL_HUMAN 153-332 pdb_monomer 153 332 monomer 3f74 99.4 C C ITAL_HUMAN 153-332 pdb_monomer 153 332 monomer 3f74 99.4 B B ITAL_HUMAN 153-332 pdb_monomer 153 331 monomer 3eob 100.0 F J ITAL_HUMAN 153-331 pdb_monomer 153 331 monomer 3eoa 100.0 F J ITAL_HUMAN 153-331 pdb_monomer 153 331 monomer 3eob 100.0 C I ITAL_HUMAN 153-331 pdb_monomer 153 331 monomer 3eoa 100.0 E I ITAL_HUMAN 153-331 pdb_monomer 154 331 monomer 2ica 100.0 A A ITAL_HUMAN 154-331 pdb_monomer 153 332 monomer 3hi6 98.3 B B ITAL_HUMAN 153-332 pdb_monomer 153 332 monomer 3hi6 98.3 A A ITAL_HUMAN 153-332 pdb_monomer 153 331 monomer 1mjn 98.9 A A ITAL_HUMAN 153-331 pdb_monomer 154 332 monomer 3tcx 98.9 Z Z ITAL_HUMAN 154-332 pdb_monomer 154 332 monomer 3tcx 98.9 V V ITAL_HUMAN 154-332 pdb_monomer 154 332 monomer 3tcx 98.9 T T ITAL_HUMAN 154-332 pdb_monomer 154 332 monomer 3tcx 98.9 R R ITAL_HUMAN 154-332 pdb_monomer 154 332 monomer 3tcx 98.9 L L ITAL_HUMAN 154-332 pdb_monomer 154 332 monomer 3tcx 98.9 J J ITAL_HUMAN 154-332 pdb_monomer 154 332 monomer 3tcx 98.9 H H ITAL_HUMAN 154-332 pdb_monomer 154 332 monomer 3tcx 98.9 X X ITAL_HUMAN 154-332 pdb_monomer 154 332 monomer 3tcx 98.9 BA b ITAL_HUMAN 154-332 pdb_monomer 154 332 monomer 3tcx 98.9 F F ITAL_HUMAN 154-332 pdb_monomer 154 332 monomer 3tcx 98.9 D D ITAL_HUMAN 154-332 pdb_monomer 154 332 monomer 3tcx 98.9 B B ITAL_HUMAN 154-332 pdb_monomer 154 332 monomer 3tcx 98.9 P P ITAL_HUMAN 154-332 pdb_monomer 154 332 monomer 3tcx 98.9 N N ITAL_HUMAN 154-332 pdb_monomer 155 331 monomer 1mq8 98.9 D D ITAL_HUMAN 155-331 pdb_monomer 155 331 monomer 1mq8 98.9 B B ITAL_HUMAN 155-331 pdb_monomer 154 332 monomer 3bn3 98.3 A A ITAL_HUMAN 154-332 pdb_monomer 153 327 monomer 1xuo 99.4 B B ITAL_HUMAN 153-327 pdb_monomer 153 325 monomer 1mqa 98.8 A A ITAL_HUMAN 153-325 pdb_monomer 153 325 monomer 1mq9 98.8 A A ITAL_HUMAN 153-325 pdb_monomer 153 331 monomer 6bxb 99.4 A A ITB3_HUMAN:ITAL_HUMAN:ITB3_HUMAN 153-331 pdb_monomer 153 331 monomer 6bxf 99.4 A A ITB3_HUMAN:ITAL_HUMAN:ITB3_HUMAN 153-331 pdb_monomer 153 331 monomer 6bxf 99.4 B B ITB3_HUMAN:ITAL_HUMAN:ITB3_HUMAN 153-331 pdb_monomer 153 331 monomer 6ckb 99.4 A A ITB3_HUMAN:ITAL_HUMAN:ITB3_HUMAN 153-331 pdb_monomer 153 331 monomer 6ckb 99.4 B B ITB3_HUMAN:ITAL_HUMAN:ITB3_HUMAN 153-331 pdb_monomer 153 331 monomer 6bxb 99.4 B B ITB3_HUMAN:ITAL_HUMAN:ITB3_HUMAN 153-331 pdb_monomer 153 331 monomer 6bxj 99.4 A A ITB3_HUMAN:ITAL_HUMAN:ITB3_HUMAN 153-331 pdb_monomer 153 325 monomer 1t0p 98.3 A A ITAL_HUMAN 153-325 pdb_monomer 26 1024 monomer 7usl 37.2 A A ITAM_HUMAN 26-37:40-137:345-378:380-411:413-437:440-641:643-734:738-742:745-902:904-955:959-967:969-1011:1014-1024 pdb_monomer 26 1024 monomer 7usm 37.3 A A ITAM_HUMAN 26-37:40-137:348-378:380-411:413-437:440-643:645-733:737-742:745-902:904-955:959-967:969-1011:1014-1024 pdb_monomer 26 1072 monomer 3k72 37.7 A A ITAX_HUMAN 26-42:45-132:343-384:386-407:409-437:440-507:510-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 1072 monomer 3k71 37.7 C C ITAX_HUMAN 26-42:45-132:343-384:386-407:409-437:440-507:510-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 1072 monomer 3k6s 37.5 G G ITAX_HUMAN 26-42:45-132:343-384:386-407:409-437:440-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 1072 monomer 3k6s 37.5 C C ITAX_HUMAN 26-42:45-132:343-384:386-407:409-437:440-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 1072 monomer 3k6s 37.5 E E ITAX_HUMAN 26-42:45-132:344-384:386-407:409-437:440-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 1072 monomer 5es4 37.5 C C ITAX_HUMAN 26-42:45-132:343-384:386-407:409-437:440-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 1072 monomer 5es4 37.5 E E ITAX_HUMAN 26-42:45-132:343-384:386-407:409-437:440-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 1072 monomer 5es4 37.5 G G ITAX_HUMAN 26-42:45-132:343-384:386-407:409-437:440-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 1072 monomer 3k71 37.4 E E ITAX_HUMAN 26-42:45-132:345-384:386-407:409-437:440-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 1072 monomer 3k72 37.4 C C ITAX_HUMAN 26-42:45-132:345-384:386-407:409-437:440-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 26 1072 monomer 3k71 37.4 A A ITAX_HUMAN 26-42:45-132:347-384:386-407:409-437:440-643:645-733:746-853:855-904:909-978:981-1007:1009-1048:1050-1072 pdb_monomer 152 911 monomer 8zjf 34.0 B A ITAE_HUMAN 152-342:346-421:423-439:442-631:643-700:702-738:746-789:791-831:834-840:842-855:859-886:891-911 pdb_monomer 322 761 monomer 4irz 34.4 A A 322-331:336-380:383-441:444-478:480-517:519-624:626-644:647-658:661-668:671-733:738-752:754-761 pdb_monomer 322 733 monomer 3v4p 34.7 C C ITA4_HUMAN 322-331:336-380:383-441:444-478:480-517:519-623:625-644:647-658:661-668:671-733 pdb_monomer 322 733 monomer 3v4p 34.7 A A ITA4_HUMAN 322-331:336-380:383-441:444-478:480-517:519-624:626-644:647-658:661-668:671-733 pdb_monomer 322 733 monomer 3v4v 34.7 A A ITA4_HUMAN 322-331:336-380:383-441:444-478:480-517:519-624:626-644:647-658:661-668:671-733 pdb_monomer 322 733 monomer 3v4v 34.7 E C ITA4_HUMAN 322-331:336-380:383-441:444-478:480-517:519-623:625-644:647-658:661-668:671-733 pdb_monomer 353 901 monomer 7nxd 32.2 A A ITA5_HUMAN 353-437:442-478:480-636:639-657:665-733:736-745:754-786:788-832:834-852:856-867:869-901 pdb_monomer 156 334 monomer 1n3y 39.3 A A ITAX_HUMAN 156-276:278-334 pdb_monomer 156 337 monomer 8voh 36.3 A A ITAM_HUMAN 156-337 pdb_monomer 1113 1170 monomer 2k8o 98.3 A A ITAL_HUMAN 1113-1170 pdb_monomer 156 336 monomer 1bhq 35.9 B 2 ITAM_HUMAN 156-336 pdb_monomer 156 336 monomer 1bhq 35.9 A 1 ITAM_HUMAN 156-336 pdb_monomer 156 336 monomer 1idn 35.9 B 2 ITAM_HUMAN 156-336 pdb_monomer 156 336 monomer 1idn 35.9 A 1 ITAM_HUMAN 156-336 pdb_monomer 156 336 monomer 1bho 35.9 B 2 ITAM_HUMAN 156-336 pdb_monomer 156 336 monomer 1bho 35.9 A 1 ITAM_HUMAN 156-336 pdb_monomer 156 335 monomer 3q3g 35.6 L L ITAM_HUMAN 156-335 pdb_monomer 156 335 monomer 3q3g 35.6 I I ITAM_HUMAN 156-335 pdb_monomer 156 335 monomer 3q3g 35.6 C G ITAM_HUMAN 156-335 pdb_monomer 156 335 monomer 3q3g 35.6 F E ITAM_HUMAN 156-335 pdb_monomer 353 762 monomer 3vi4 32.6 A A ITA5_HUMAN 353-437:442-478:480-636:639-657:665-733:736-745:754-762 pdb_monomer 353 762 monomer 3vi3 32.6 A A ITA5_HUMAN 353-437:442-478:480-636:639-657:665-733:736-745:754-762 pdb_monomer 156 336 monomer 8ce6 35.9 A