type start end name pdb_id identity asym_id_homo oper_homo auth_asym_id_homo mol_id_homo asym_id_con oper_con auth_asym_id_con mol_id_con sites description_homo description_con length 1 498 id 1 498 IRF5_HUMAN title 1 498 RecName: Full=Interferon regulatory factor 5 ; Short=IRF-5 ; seq 1 498 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLRPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMVEQFKELHHIWQSQQRLQPVAQAPPGAGLGVGQGPWPMHPAGMQ uniprot 1 498 CHAIN /note="Interferon regulatory factor 5" /id="PRO_0000154558" uniprot 14 122 DNA_BIND /note="IRF tryptophan pentad repeat" uniprot 121 207 REGION /note="Disordered" uniprot 478 498 REGION /note="Disordered" uniprot 169 206 COMPBIAS /note="Pro residues" disorder 1 12 predicted_by_DISOPRED disorder 127 212 predicted_by_DISOPRED disorder 215 217 predicted_by_DISOPRED disorder 222 236 predicted_by_DISOPRED disorder 473 482 predicted_by_DISOPRED disorder 485 486 predicted_by_DISOPRED disorder 490 493 predicted_by_DISOPRED disorder 498 498 predicted_by_DISOPRED pdb_monomer 232 467 monomer 3dsh 99.6 A A IRF5_HUMAN 232-467 pdb_monomer 15 123 monomer 8hcl 47.7 E A A8E5I1_DANRE 15-123 pdb_complex 293 428 hetero 5oen 33.6 A 1 A IRF9_MOUSE B 1 B Q3UDU1_MOUSE 293:294:322:323:326:328:330-332:335:337:365:368 Interferon regulatory factor 9 Signal transducer and activator of transcription[1.. pdb_complex 249 429 hetero 1zoq 35.7 A 1 A IRF3_HUMAN B 1 C CBP_HUMAN 249:267:376:379:380:383:421-423:425:426:429 Interferon regulatory factor 3 CREB-binding protein[47 aa] pdb_complex 249 447 hetero 5jem 34.9 A 1 A IRF3_HUMAN B 1 C CBP_HUMAN 249:267:376:379:380:383:421:422:425:426:428-430:432-434 Interferon regulatory factor 3 CREB-binding protein[42 aa] pdb_complex 249 447 hetero 5jem 34.9 A 1 A IRF3_HUMAN D 1 D CBP_HUMAN 303-305 Interferon regulatory factor 3 CREB-binding protein[42 aa] pdb_complex 249 446 hetero 7jfm 34.2 A 1 A IRF3_MOUSE D 1 D CBP_HUMAN 307 Interferon regulatory factor 3 CREB-binding protein[37 aa] pdb_complex 249 447 hetero 7jfm 34.9 C 1 B IRF3_MOUSE D 1 D CBP_HUMAN 249:267:376:379:380:383:421:422:425:426:428-430:433:435 Interferon regulatory factor 3 CREB-binding protein[37 aa] pdb_complex 249 459 hetero 5jej 35.2 D 1 A IRF3_HUMAN B 1 D STING_HUMAN 313:316:317:320:338:341-343:345:363:400-402:411:413 Interferon regulatory factor 3 Stimulator of interferon genes protein[10 aa] pdb_complex 249 459 hetero 5jej 35.2 D 1 A IRF3_HUMAN C 1 E STING_HUMAN 388:389 Interferon regulatory factor 3 Stimulator of interferon genes protein[4 aa] pdb_complex 249 459 hetero 5jej 35.2 E 1 B IRF3_HUMAN C 1 E STING_HUMAN 257:310:311:313:411 Interferon regulatory factor 3 Stimulator of interferon genes protein[4 aa] pdb_complex 249 459 hetero 5jej 35.2 E 1 B IRF3_HUMAN A 1 C STING_HUMAN 313:316:317:320:338:340-343:345:363:400-402:413 Interferon regulatory factor 3 Stimulator of interferon genes protein[21 aa] pdb_complex 249 459 hetero 5jek 35.2 A 1 A IRF3_HUMAN C 1 C 313:316:320:338:340-343:363:400:401:413 Interferon regulatory factor 3 MAVS peptide[14 aa] pdb_complex 249 459 hetero 5jek 35.2 B 1 B IRF3_HUMAN D 1 D 313:316:317:320:338:340-343:363:400 Interferon regulatory factor 3 MAVS peptide[16 aa] pdb_complex 249 459 hetero 5jel 35.2 A 1 A IRF3_HUMAN B 1 B 257:313:316:317:320:338:341-343:345:363:400-402:407:412 Interferon regulatory factor 3 Phosphorylated TRIF peptide[14 aa] pdb_complex 249 459 hetero 5jeo 35.2 B 1 A IRF3_HUMAN A 1 B 257:311:313:316:320:338:340-343:345:363:400-402:411:413 Interferon regulatory factor 3 Rotavirus NSP1 peptide[10 aa] pdb_complex 249 459 hetero 5jer 35.2 E 1 A IRF3_HUMAN A 1 B 257:311:313:316:317:320:341:343:345:400-402:411:413 Interferon regulatory factor 3 Rotavirus NSP1 peptide[10 aa] pdb_complex 249 459 hetero 5jer 35.2 F 1 C IRF3_HUMAN D 1 H 389 Interferon regulatory factor 3 Rotavirus NSP1 peptide[10 aa] pdb_complex 16 123 hetero 1t2k 44.3 C 1 A IRF3_HUMAN F 1 D ATF2_HUMAN 52-54 Interferon regulatory factor 3 Cyclic-AMP-dependent transcription factor ATF-2[61.. pdb_complex 16 120 nucleotide 1if1 42.9 C 1 A IRF1_MOUSE A 1 C 20:21:47:49-53:67:71:73:84:87:89:91-93:95-97:108:109 PROTEIN (INTERFERON REGULATORY FACTOR 1) DNA (26-MER) pdb_complex 16 120 nucleotide 1if1 42.9 C 1 A IRF1_MOUSE B 1 D 17:20 PROTEIN (INTERFERON REGULATORY FACTOR 1) DNA (26-MER) pdb_complex 14 120 nucleotide 2irf 43.9 G 1 G IRF2_MOUSE F 1 F 16:17:67:71:73:89:92:93:96:97 INTERFERON REGULATORY FACTOR 2 DNA (5'-D(*TP*TP*CP*AP*CP*TP*TP*TP*CP*AP*CP*(5IU)P.. pdb_complex 14 120 nucleotide 2irf 43.9 H 1 H IRF2_MOUSE A 1 A 47-51:84:87:91:92:95:116 INTERFERON REGULATORY FACTOR 2 DNA (5'-D(P*AP*AP*GP*TP*GP*AP*AP*AP*GP*(5IU)P*GP*A.. pdb_complex 14 120 nucleotide 2irf 43.9 I 1 I IRF2_MOUSE E 1 E 16:17:67:71:73:89:92:93:96:97 INTERFERON REGULATORY FACTOR 2 DNA (5'-D(*TP*TP*CP*AP*CP*TP*TP*TP*CP*AP*CP*(5IU)P.. pdb_complex 16 123 nucleotide 1t2k 44.3 C 1 A IRF3_HUMAN A 1 E 47:49-51:84:87:91:96:116 Interferon regulatory factor 3 31-MER pdb_complex 16 123 nucleotide 1t2k 44.3 C 1 A IRF3_HUMAN B 1 F 16:17:49:51-53:67:71:88:89:92:93:96:97:108 Interferon regulatory factor 3 31-MER pdb_complex 16 123 nucleotide 2o6g 44.3 C 1 E IRF3_HUMAN A 1 D 47:49-51:84:87:88:91:92:96:105:116 Interferon regulatory factor 3 interferon-b enhancer pdb_complex 16 123 nucleotide 2o6g 44.3 C 1 E IRF3_HUMAN B 1 C 16:17:49:51-53:67:71:88:89:92:96:97:108 Interferon regulatory factor 3 interferon-b enhancer pdb_complex 16 124 nucleotide 7ogs 45.0 A 1 A IRF4_HUMAN C 1 C 16:17:49:67:71:73:88:89:92:93:96 Interferon regulatory factor 4 DNA (5'-D(P*TP*GP*TP*AP*CP*TP*TP*TP*CP*GP*GP*TP*TP.. pdb_complex 16 124 nucleotide 7ogs 45.0 A 1 A IRF4_HUMAN D 1 D 47-50:84:87:88:91:92:95:96:116 Interferon regulatory factor 4 DNA (5'-D(P*AP*TP*AP*AP*CP*TP*GP*AP*AP*AP*CP*CP*GP.. pdb_complex 16 124 nucleotide 7oot 45.0 A 1 A IRF4_HUMAN C 1 C 47-50:84:87:91:92:95:96:116 Interferon regulatory factor 4 DNA (5'-D(P*TP*CP*AP*AP*CP*TP*GP*AP*AP*AP*CP*CP*GP.. pdb_complex 16 124 nucleotide 7oot 45.0 A 1 A IRF4_HUMAN D 1 E 16:17:49:51-53:67:71:73:89:96:98 Interferon regulatory factor 4 DNA (5'-D(P*AP*GP*CP*TP*TP*TP*CP*TP*CP*GP*GP*TP*TP.. pdb_complex 16 121 nucleotide 2pi0 46.9 C 1 A IRF3_HUMAN A 1 E 47-51:84:87:88:91:95:96:116 Interferon regulatory factor 3 PRDIII-I region of human interferon-B promoter str.. pdb_complex 16 121 nucleotide 2pi0 46.9 C 1 A IRF3_HUMAN B 1 F 16:17:49:51:67:71:89:92:93:96:97 Interferon regulatory factor 3 PRDIII-I region of human interferon-B promoter str.. pdb_complex 19 122 nucleotide 2o61 45.1 C 1 A TF65_HUMAN:IRF7_HUMAN:IRF3_HUMAN A 1 E 47-51:84:87:88:91:96:116 Transcription factor p65/Interferon regulatory fac.. 36-MER pdb_complex 19 122 nucleotide 2o61 45.1 C 1 A TF65_HUMAN:IRF7_HUMAN:IRF3_HUMAN B 1 F 49:51-53:67:71:85:88:89:92:96:97:108 Transcription factor p65/Interferon regulatory fac.. 34-MER pdb_complex 16 121 nucleotide 8jkn 45.3 C 1 C F2Z3D5_HUMAN A 1 A 47-50:84:87:91:92:95:116 Interferon regulatory factor 4 GAAA-Forward pdb_complex 16 121 nucleotide 8jkn 45.3 C 1 C F2Z3D5_HUMAN B 1 B 16:17:67:71:73:88:89:92:96:109 Interferon regulatory factor 4 GAAA-Reverse pdb_complex 16 121 nucleotide 8jkq 44.8 C 1 D F2Z3D5_HUMAN A 1 A 47:49:50:84:87:88:91:95:116 Interferon regulatory factor 4 GACA-Forward pdb_complex 16 121 nucleotide 8jkq 44.8 C 1 D F2Z3D5_HUMAN B 1 B 16:17:49:52:67:71:73:88:89:92:96 Interferon regulatory factor 4 GACA-Reverse pdb_complex 16 121 nucleotide 8jks 45.3 C 1 C F2Z3D5_HUMAN A 1 A 47-50:84:87:91:95 Interferon regulatory factor 4 GAGA-Forward pdb_complex 16 121 nucleotide 8jks 45.3 C 1 C F2Z3D5_HUMAN B 1 B 16:17:49:52:67:71:73:88:89:92:96 Interferon regulatory factor 4 GAGA-Reverse pdb_complex 16 121 nucleotide 7jm4 45.3 C 1 B IRF4_HUMAN A 1 D 47-50:84:87:88:91:92:95 Interferon regulatory factor 4 Interferon-Stimulated Response Elements pdb_complex 16 121 nucleotide 7jm4 45.3 C 1 B IRF4_HUMAN B 1 E 16:17:67:71:73:89:92:96:109 Interferon regulatory factor 4 Interferon-Stimulated Response Elements pdb_complex 16 121 nucleotide 7rh2 46.2 G 1 G Q99419_HUMAN F 1 F 16:17:52:67:71:73:89:92:93:96 ICSAT transcription factor DNA (5'-D(*GP*CP*TP*TP*TP*CP*TP*CP*GP*GP*TP*TP*TP*.. pdb_complex 16 120 nucleotide 8hcm 47.4 A 1 A Q1RLP9_DANRE B 1 B 47-50:84:87:91:92:95:116 Interferon regulatory factor DNA (5'-D(P*TP*AP*GP*AP*AP*AP*GP*TP*GP*AP*AP*AP*GP.. pdb_complex 16 120 nucleotide 8hcm 47.4 A 1 A Q1RLP9_DANRE C 1 C 16:17:49:51-53:67:71:73:89:92:93:96:97 Interferon regulatory factor DNA (5'-D(P*GP*CP*TP*TP*TP*CP*AP*CP*TP*TP*TP*CP*TP.. pdb_complex 16 121 nucleotide 8jkl 48.0 E 1 G F2Z3D5_HUMAN C 1 E 47-50:84:87:88:91:92:95 Interferon regulatory factor 4 GATA-Forward pdb_complex 16 121 nucleotide 8jkl 48.0 E 1 G F2Z3D5_HUMAN D 1 F 16:17:67:71:73:89:92:93:96 Interferon regulatory factor 4 GATA-Reverse pdb_complex 15 123 nucleotide 8hcl 47.7 E 1 A A8E5I1_DANRE A 1 C 47-50:84:87:88:91:92:95 Interferon regulatory factor 10 DNA (5'-D(P*TP*GP*AP*AP*GP*TP*GP*AP*AP*AP*GP*T)-3'.. pdb_complex 15 123 nucleotide 8hcl 47.7 E 1 A A8E5I1_DANRE B 1 D 16:17:49:51:67:71:73:89:92:93:96 Interferon regulatory factor 10 DNA (5'-D(P*AP*CP*TP*TP*TP*CP*AP*CP*TP*TP*CP*A)-3'.. pdb_complex 14 120 metal 2irf 43.9 G 1 G IRF2_MOUSE M 1 G K 94:95:97:100 INTERFERON REGULATORY FACTOR 2 POTASSIUM ION[1 atoms] pdb_complex 16 121 metal 3qu6 45.8 A 1 A Q7Z5G6_HUMAN H 1 A CL 106:109:113:115 IRF3 protein CHLORIDE ION[1 atoms] pdb_complex 16 121 metal 3qu6 45.8 A 1 A Q7Z5G6_HUMAN I 1 A CL 26 IRF3 protein CHLORIDE ION[1 atoms] pdb_complex 16 121 metal 3qu6 45.8 A 1 A Q7Z5G6_HUMAN M 1 A CL 61:65:66:69 IRF3 protein CHLORIDE ION[1 atoms] pdb_complex 241 426 metal 5bvi 42.1 A 1 A Q5SUZ4_MOUSE C 1 A CL 320-323:340:341 Interferon regulatory factor 4 CHLORIDE ION[1 atoms] pdb_complex 241 426 metal 5bvi 42.1 A 1 A Q5SUZ4_MOUSE D 1 A CL 273:275-277:279:322 Interferon regulatory factor 4 CHLORIDE ION[1 atoms] pdb_complex 241 426 metal 5bvi 42.1 A 1 A Q5SUZ4_MOUSE E 1 A CL 292:294 Interferon regulatory factor 4 CHLORIDE ION[1 atoms] pdb_complex 16 124 metal 6td4 44.7 A 1 A IRF4_HUMAN B 1 A CL 44 Interferon regulatory factor 4 CHLORIDE ION[1 atoms] pdb_complex 16 121 metal 3qu6 45.8 A 1 A Q7Z5G6_HUMAN D 1 A ZN 65:69 IRF3 protein ZINC ION[1 atoms] pdb_complex 16 121 metal 3qu6 45.8 A 1 A Q7Z5G6_HUMAN E 1 A ZN 22:26 IRF3 protein ZINC ION[1 atoms] pdb_complex 16 121 metal 3qu6 45.8 A 1 A Q7Z5G6_HUMAN F 1 A ZN 109:112 IRF3 protein ZINC ION[1 atoms] pdb_complex 16 121 metal 3qu6 45.8 A 1 A Q7Z5G6_HUMAN G 1 A ZN 104:106:115:117 IRF3 protein ZINC ION[1 atoms] pdb_complex 14 121 metal 3qu3 41.5 A 1 A IRF7_MOUSE D 1 A NA 94:95:97:100 Interferon regulatory factor 7 SODIUM ION[1 atoms] pdb_complex 16 121 metal 3qu6 45.8 A 1 A Q7Z5G6_HUMAN K 1 A NA 32:34 IRF3 protein SODIUM ION[1 atoms] pdb_complex 16 121 metal 3qu6 45.8 A 1 A Q7Z5G6_HUMAN L 1 A NA 60:62:64:65:83 IRF3 protein SODIUM ION[1 atoms] pdb_complex 243 428 homo 5oem 34.5 A 1 A IRF9_MOUSE A 2 A IRF9_MOUSE 271:294:323:326-328:330:332:335:337:365 Interferon regulatory factor 9 Interferon regulatory factor 9[189 aa] pdb_complex 249 446 homo 7jfm 34.2 A 1 A IRF3_MOUSE C 1 B IRF3_MOUSE 255:257-259:307-310:313:316:317:338:341-343:350:352:353:363:400-402:409:410:413:428:431:432:435-438:441:443-446 Interferon regulatory factor 3 Interferon regulatory factor 3[194 aa] pdb_complex 249 459 homo 1qwt 35.2 A 1 A IRF3_HUMAN B 1 B IRF3_HUMAN 260:263:434-439 Interferon regulatory factor 3 Interferon regulatory factor 3[239 aa] pdb_complex 249 459 homo 1qwt 35.2 B 1 B IRF3_HUMAN A 1 A IRF3_HUMAN 255:258:260:356-359:396:433:434 Interferon regulatory factor 3 Interferon regulatory factor 3[239 aa] pdb_complex 249 459 homo 5jej 35.2 D 1 A IRF3_HUMAN E 1 B IRF3_HUMAN 255:258:304-307:354:356:357:360:382:383:385:408-410:430:431:433:434 Interferon regulatory factor 3 Interferon regulatory factor 3[233 aa] pdb_complex 16 123 homo 2o6g 44.3 C 1 E IRF3_HUMAN E 1 G IRF3_HUMAN 16:19:98 Interferon regulatory factor 3 Interferon regulatory factor 3[110 aa] pdb_complex 16 123 homo 2o6g 44.3 E 1 G IRF3_HUMAN C 1 E IRF3_HUMAN 51:53:112 Interferon regulatory factor 3 Interferon regulatory factor 3[110 aa] pdb_complex 16 121 homo 2pi0 45.2 E 1 C IRF3_HUMAN C 1 A IRF3_HUMAN 53 Interferon regulatory factor 3 Interferon regulatory factor 3[98 aa] pdb_complex 232 467 homo 3dsh 99.6 A 1 A IRF5_HUMAN A 2 A IRF5_HUMAN 257:258:278:279:285:287-289:307:309:310:313:316:317:319:320:322:323:338:341-343:345:363:364:382:383:385:388:390:400-402:406-408:410:411:413:428:431:432:434:435:439-449:451:452:455:456:458:459:462 Interferon regulatory factor 5 Interferon regulatory factor 5[236 aa] pdb_complex 249 459 precipitant 3a77 36.7 A 1 A IRF3_HUMAN F 1 A MPD 270:289:326:328:337 Interferon regulatory factor 3 (4S)-2-METHYL-2,4-PENTANEDIOL[8 atoms] pdb_complex 249 459 precipitant 3a77 36.7 A 1 A IRF3_HUMAN E 1 A ACY 345:407-409 Interferon regulatory factor 3 ACETIC ACID[4 atoms] pdb_complex 14 120 precipitant 3qu3 41.9 B 1 B IRF7_MOUSE F 1 B EDO 102:103 Interferon regulatory factor 7 1,2-ETHANEDIOL[4 atoms] pdb_complex 14 120 precipitant 3qu3 41.9 B 1 B IRF7_MOUSE G 1 B EDO 23:26:27 Interferon regulatory factor 7 1,2-ETHANEDIOL[4 atoms] pdb_complex 14 121 precipitant 3qu3 41.5 C 1 C IRF7_MOUSE J 1 C EDO 74:77:78 Interferon regulatory factor 7 1,2-ETHANEDIOL[4 atoms] pdb_complex 249 459 precipitant 1qwt 35.2 A 1 A IRF3_HUMAN C 1 A PO4 319:320:322:341 Interferon regulatory factor 3 PHOSPHATE ION[5 atoms] pdb_complex 249 459 precipitant 1qwt 35.2 A 1 A IRF3_HUMAN D 1 A PO4 250:268:329 Interferon regulatory factor 3 PHOSPHATE ION[5 atoms] pdb_complex 249 459 precipitant 1qwt 35.2 A 1 A IRF3_HUMAN E 1 A PO4 270:295:328 Interferon regulatory factor 3 PHOSPHATE ION[5 atoms] pdb_complex 249 459 precipitant 1qwt 35.2 B 1 B IRF3_HUMAN I 1 B PO4 449-451 Interferon regulatory factor 3 PHOSPHATE ION[5 atoms] pdb_complex 249 459 precipitant 1qwt 35.2 B 1 B IRF3_HUMAN J 1 B PO4 313:316:401 Interferon regulatory factor 3 PHOSPHATE ION[5 atoms] pdb_complex 249 459 precipitant 5jeo 35.2 B 1 A IRF3_HUMAN C 1 A PO4 378:389:391:392 Interferon regulatory factor 3 PHOSPHATE ION[5 atoms] pdb_complex 249 459 precipitant 5jeo 35.2 B 1 A IRF3_HUMAN D 2 A PO4 257:308:311 Interferon regulatory factor 3 PHOSPHATE ION[5 atoms] pdb_complex 249 459 precipitant 5jeo 35.2 B 1 A IRF3_HUMAN E 1 A PO4 385:388 Interferon regulatory factor 3 PHOSPHATE ION[5 atoms] pdb_complex 243 428 precipitant 5oem 34.5 A 1 A IRF9_MOUSE B 1 A PO4 332:368:371-373 Interferon regulatory factor 9 PHOSPHATE ION[5 atoms] pdb_complex 16 124 precipitant 7oot 45.0 B 1 B IRF4_HUMAN E 1 B PO4 111:112 Interferon regulatory factor 4 PHOSPHATE ION[5 atoms]