Contact Molecules for Homologous Proteins


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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
3652451 207 40 P51149(RAB7A_HUMAN) RecName: Full=Ras-related protein Rab-7a ; EC=3.6.5.2 ;
QUERYSEQ
MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIP
YFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [P51149(RAB7A_HUMAN)]

207
region name description
2-207 CHAIN /note="Ras-related protein Rab-7a" /id="PRO_0000121121"
15-22 BINDING /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" ECO:0000269|PubMed:20028791"
34-40 BINDING /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" ECO:0000269|PubMed:20028791"
63-67 BINDING /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" ECO:0000269|PubMed:20028791"
125-128 BINDING /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" ECO:0000269|PubMed:20028791"
156-157 BINDING /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565" ECO:0000269|PubMed:20028791"
205-205 LIPID /note="S-geranylgeranyl cysteine"
207-207 LIPID /note="S-geranylgeranyl cysteine"
1-207 DISORDER predicted by DISOPRED

MONOMER
207
pdb_id a1 identity[%]2 description
1vg8 D 100.0 RAB7_RAT Ras-related protein Rab-7
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue.
HETERO
207 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1vg0[1] A RAE1_RAT Rab proteins geranylgeranyltransferase component A.. B 100.0
/100.0
24
/24
RAB7_RAT Ras-related protein Rab-7
1vg9[4] A RAE1_RAT Rab proteins geranylgeranyltransferase component A.. B 100.0
/100.0
19
/19
RAB7_RAT Ras-related protein Rab-7
1yhn[2] B RILP_HUMAN Rab interacting lysosomal protein[65 aa] A 100.0
/99.5
13
/13
RAB7_HUMAN Ras-related protein Rab-7
1yhn[2] B RILP_HUMAN Rab interacting lysosomal protein[65 aa] A 100.0
/99.5
17
/17
RAB7_HUMAN Ras-related protein Rab-7
6iyb[3] B OSBL1_HUMAN Oxysterol-binding protein-related protein 1[135 aa.. A 100.0
/99.4
12
/12
RAB7A_HUMAN Ras-related protein Rab-7a
6wcw[1] B RUBIC_HUMAN Run domain Beclin-1-interacting and cysteine-rich .. A 100.0
/99.4
18
/18
RAB7A_HUMAN Ras-related protein Rab-7a
7f6j[2] C PDZD8_HUMAN PDZ domain-containing protein 8[106 aa] A 100.0
/99.4
26
/26
RAB7A_HUMAN Ras-related protein Rab-7a
8kb8[2] A WDR91_HUMAN WD repeat-containing protein 91[338 aa] C 100.0
/99.4
17
/17
RAB7A_HUMAN Ras-related protein Rab-7a
5z2m[1] A OSBL1_MOUSE Oxysterol-binding protein-related protein 1[137 aa.. B 88.9
/99.4
9
/9
RAB7A_MOUSE Ras-related protein Rab-7a
5z2m[1] D OSBL1_MOUSE Oxysterol-binding protein-related protein 1[136 aa.. C 100.0
/99.4
7
/7
RAB7A_MOUSE Ras-related protein Rab-7a
5ldd[2] A G0SGS3_CHATD Mon1[155 aa] C 95.0
/85.1
20
/20
G0SGE1_CHATD Rab small monomeric GTPase-like protein
5ldd[2] B G0SD94_CHATD Ccz1[166 aa] C 100.0
/85.1
6
/6
G0SGE1_CHATD Rab small monomeric GTPase-like protein
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
COMPOUND
207 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1ky3[8] C GDP
GUANOSINE-5'-DIPHOSPHATE[28 atoms]
A 93.3
/67.3
15
/15
YPT7_YEAST GTP-BINDING PROTEIN YPT7P
1ky2[10] C GNP
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER[32 ato..
A 90.0
/70.1
20
/20
YPT7_YEAST GTP-BINDING PROTEIN YPT7P
1t91[15] F GTP
GUANOSINE-5'-TRIPHOSPHATE[32 atoms]
A 100.0
/99.4
23
/23
RAB7_HUMAN Ras-related protein Rab-7
4phh[4] E 2UK
5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonoamino)phos..
A 90.0
/69.5
20
/20
YPT7_YEAST GTP-binding protein YPT7
4phg[1] C 2UJ
N-[3-(propanoylamino)propyl]guanosine 5'-(tetrahyd..
A 91.3
/68.4
23
/23
YPT7_YEAST GTP-binding protein YPT7
4phf[1] B 2UH
N-[3-(propanoylamino)propyl]guanosine 5'-(trihydro..
A 87.5
/67.3
16
/16
YPT7_YEAST GTP-binding protein YPT7
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
METAL
207 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1vg9[4] J K
POTASSIUM ION[1 atoms]
B 100.0
/100.0
1
/1
RAB7_RAT Ras-related protein Rab-7
1ky2[24] B MG
MAGNESIUM ION[1 atoms]
A 100.0
/70.1
2
/2
YPT7_YEAST GTP-BINDING PROTEIN YPT7P
4phf[7] C MG
MAGNESIUM ION[1 atoms]
A 100.0
/67.3
1
/1
YPT7_YEAST GTP-binding protein YPT7
6iyb[6] E MG
MAGNESIUM ION[1 atoms]
A 100.0
/99.4
2
/2
RAB7A_HUMAN Ras-related protein Rab-7a
4phh[1] G CL
CHLORIDE ION[1 atoms]
A 0.0
/69.5
1
/1
YPT7_YEAST GTP-binding protein YPT7
4phh[2] J CL
CHLORIDE ION[1 atoms]
B 80.0
/69.3
5
/5
YPT7_YEAST GTP-binding protein YPT7
4phg[1] D YT3
YTTRIUM (III) ION[1 atoms]
A 0.0
/68.4
1
/1
YPT7_YEAST GTP-binding protein YPT7
4phg[1] E YT3
YTTRIUM (III) ION[1 atoms]
A 100.0
/68.4
2
/2
YPT7_YEAST GTP-binding protein YPT7
4phg[1] F YT3
YTTRIUM (III) ION[1 atoms]
A 100.0
/68.4
1
/1
YPT7_YEAST GTP-binding protein YPT7
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
PRECIPITANT
207 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1vg0[1] G PG4
TETRAETHYLENE GLYCOL[13 atoms]
B 100.0
/100.0
4
/4
RAB7_RAT Ras-related protein Rab-7
1vg9[4] L P33
3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL[22 atoms]
B 100.0
/100.0
5
/5
RAB7_RAT Ras-related protein Rab-7
5ldd[2] G SO4
SULFATE ION[5 atoms]
C 100.0
/85.1
8
/8
G0SGE1_CHATD Rab small monomeric GTPase-like protein
5ldd[1] H SO4
SULFATE ION[5 atoms]
C 80.0
/85.1
5
/5
G0SGE1_CHATD Rab small monomeric GTPase-like protein
4phf[1] D NO3
NITRATE ION[4 atoms]
A 66.7
/67.3
6
/6
YPT7_YEAST GTP-binding protein YPT7
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.