HOMCOS(prot_sch_conbars.cgi):

		Contact Molecules for Homologous Proteins
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PID	QueryLength	Homolgous Sequence in PDB	UniProt Query	TITLE
2711687	385	31	P35613(BASI_HUMAN)	RecName: Full=Basigin ;AltName: Full=5F7;AltName: Full=Collagenase stimulatory factor;AltName: Full=Extracellular matrix metalloproteinase inducer; Short=EMMPRIN;AltName: Full=Hepatoma-associated antigen ; Short=HAb18G ;AltName: Full=Leukocyte activation antigen M6;AltName: Full=OK blood group antigen;AltName: Full=Tumor cell-derived collagenase stimulatory factor; Short=TCSF;AltName: CD_antigen=CD147;Flags: Precursor;
QUERYSEQ	MAAALFVLLGFALLGTHGASGAAGFVQAPLSQQRWVGGSVELHCEAVGSPVPEIQWWFEGQGPNDTCSQLWDGARLDRVHIHATYHQHAASTISIDTLVEEDTGTYECRASNDPDRNHLTRAPRVKWVRAQAVVLVLEPGTVFTTVEDLG SKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYR CNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS

[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [P35613(BASI_HUMAN)]

385
	region	name	description
	1-21	SIGNAL
	22-385	CHAIN	/note="Basigin" /id="PRO_0000014518"
	138-323	TOPO_DOM	/note="Extracellular"
	324-344	TRANSMEM	/note="Helical"
	345-385	TOPO_DOM	/note="Cytoplasmic"
	37-120	DOMAIN	/note="Ig-like"
	138-219	DOMAIN	/note="Ig-like C2-type"
	221-315	DOMAIN	/note="Ig-like V-type"
	353-385	REGION	/note="Disordered"
	356132195-199	REGION	/note="Essential for interaction with KDR/VEGFR2"
	1-385	DISORDER	predicted by DISOPRED

MONOMER

385

pdb_id a¹ identity[%]² description

7da5 B 100.0 BASI_HUMAN Basigin

3qr2 A 99.1 BASI_HUMAN Basigin

1.a¹:asym_id for the homologue. 2.identity[%]²:sequence identity between the query and the homologue.

HETERO

385 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

4u0q[1] A B2L3N7_PLAFA Reticulocyte binding protein 5[286 aa] B 100.0
/100.0 24
/25 BASI_HUMAN Basigin

4u0q[1] C B2L3N7_PLAFA Reticulocyte binding protein 5[285 aa] D 100.0
/100.0 20
/21 BASI_HUMAN Basigin

5x0t[2] A 6H8 Fab fragment heavy chain[215 aa] E 100.0
/100.0 9
/9 BASI_HUMAN Basigin

5x0t[2] C 6H8 Fab fragment light chain[213 aa] E 100.0
/100.0 7
/7 BASI_HUMAN Basigin

6lyy[5] A MOT1_HUMAN Monocarboxylate transporter 1[382 aa] B 100.0
/100.0 10
/10 BASI_HUMAN Basigin

7xy8[2] C heavy chain[212 aa] A 100.0
/100.0 15
/15 BASI_HUMAN Isoform 2 of Basigin

7xy8[2] E light chain[214 aa] A 100.0
/100.0 8
/8 BASI_HUMAN Isoform 2 of Basigin

7daa[3] B Light chain of antibody Fab fragment[217 aa] A 100.0
/98.8 14
/14 BASI_HUMAN Isoform 2 of Basigin

7daa[3] C Heavy chain of antibody Fab fragment[212 aa] A 100.0
/98.8 7
/7 BASI_HUMAN Isoform 2 of Basigin

7dce[2] B XKR8_HUMAN XK-related protein 8[355 aa] A 100.0
/98.5 12
/12 BASI_HUMAN Isoform 2 of Basigin

7y1b[1] B Heavy chain of 6E7F1[214 aa] A 40.0
/50.0 10
/11 BASI_MOUSE Isoform 2 of Basigin

7y1b[1] C Light chain of 6E7F1[213 aa] A 22.2
/50.0 9
/10 BASI_MOUSE Isoform 2 of Basigin

6a69[1] A AT2B1_HUMAN Plasma membrane calcium-transporting ATPase 1[911 .. B 75.0
/47.2 16
/16 NPTN_HUMAN Neuroplastin

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

COMPOUND

385 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

6a69[1] C NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. B 75.0
/47.2 4
/4 NPTN_HUMAN Neuroplastin

6zr7[1] G NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 50.0
/40.5 2
/2 DSCAM_HUMAN Down syndrome cell adhesion molecule

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

METAL

385 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

7daa[1] D CD
CADMIUM ION[1 atoms] A 100.0
/98.8 1
/1 BASI_HUMAN Isoform 2 of Basigin

7daa[1] E CD
CADMIUM ION[1 atoms] A 100.0
/98.8 1
/1 BASI_HUMAN Isoform 2 of Basigin

7daa[1] F CD
CADMIUM ION[1 atoms] A 100.0
/98.8 1
/1 BASI_HUMAN Isoform 2 of Basigin

3i84[4] C CL
CHLORIDE ION[1 atoms] B 100.0
/98.7 1
/1 Q54A51_HUMAN Cervical EMMPRIN

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

OTHERPOLY

385 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

6zr7[1] B N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galact.. A 0.0
/40.5 1
/8 DSCAM_HUMAN Down syndrome cell adhesion molecule

6zr7[1] C beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-b.. A 0.0
/40.5 6
/6 DSCAM_HUMAN Down syndrome cell adhesion molecule

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

HOMO

385 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

3qqn[6] B BASI_HUMAN Basigin[116 aa] A 100.0
/98.3 14
/15 BASI_HUMAN Basigin

3qr2[2] A BASI_HUMAN Basigin[117 aa] A 100.0
/99.1 1
/1 BASI_HUMAN Basigin

3qr2[4] B BASI_HUMAN Basigin[116 aa] A 100.0
/99.1 7
/7 BASI_HUMAN Basigin

3qr2[2] B BASI_HUMAN Basigin[116 aa] B 100.0
/99.1 7
/7 BASI_HUMAN Basigin

3i84[6] A Q54A51_HUMAN Cervical EMMPRIN[79 aa] A 100.0
/98.7 7
/7 Q54A51_HUMAN Cervical EMMPRIN

3i84[4] B Q54A51_HUMAN Cervical EMMPRIN[85 aa] A 100.0
/98.7 36
/36 Q54A51_HUMAN Cervical EMMPRIN

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

PRECIPITANT

385 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

3b5h[1] E ACT
ACETATE ION[4 atoms] D 100.0
/100.0 2
/2 Q54A51_HUMAN Cervical EMMPRIN

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

MONOMER
385
	pdb_id	a¹	identity[%]²	description
	7da5	B	100.0	BASI_HUMAN Basigin
	3qr2	A	99.1	BASI_HUMAN Basigin
	1.a¹:asym_id for the homologue. 2.identity[%]²:sequence identity between the query and the homologue.

HETERO
385	pdb_id	contact mol		homologue
	pdb_id	a³	description	a⁴	identity[%]⁵	Ncon⁶	description
	4u0q[1]	A	B2L3N7_PLAFA Reticulocyte binding protein 5[286 aa]	B	100.0 /100.0	24 /25	BASI_HUMAN Basigin
	4u0q[1]	C	B2L3N7_PLAFA Reticulocyte binding protein 5[285 aa]	D	100.0 /100.0	20 /21	BASI_HUMAN Basigin
	5x0t[2]	A	6H8 Fab fragment heavy chain[215 aa]	E	100.0 /100.0	9 /9	BASI_HUMAN Basigin
	5x0t[2]	C	6H8 Fab fragment light chain[213 aa]	E	100.0 /100.0	7 /7	BASI_HUMAN Basigin
	6lyy[5]	A	MOT1_HUMAN Monocarboxylate transporter 1[382 aa]	B	100.0 /100.0	10 /10	BASI_HUMAN Basigin
	7xy8[2]	C	heavy chain[212 aa]	A	100.0 /100.0	15 /15	BASI_HUMAN Isoform 2 of Basigin
	7xy8[2]	E	light chain[214 aa]	A	100.0 /100.0	8 /8	BASI_HUMAN Isoform 2 of Basigin
	7daa[3]	B	Light chain of antibody Fab fragment[217 aa]	A	100.0 /98.8	14 /14	BASI_HUMAN Isoform 2 of Basigin
	7daa[3]	C	Heavy chain of antibody Fab fragment[212 aa]	A	100.0 /98.8	7 /7	BASI_HUMAN Isoform 2 of Basigin
	7dce[2]	B	XKR8_HUMAN XK-related protein 8[355 aa]	A	100.0 /98.5	12 /12	BASI_HUMAN Isoform 2 of Basigin
	7y1b[1]	B	Heavy chain of 6E7F1[214 aa]	A	40.0 /50.0	10 /11	BASI_MOUSE Isoform 2 of Basigin
	7y1b[1]	C	Light chain of 6E7F1[213 aa]	A	22.2 /50.0	9 /10	BASI_MOUSE Isoform 2 of Basigin
	6a69[1]	A	AT2B1_HUMAN Plasma membrane calcium-transporting ATPase 1[911 ..	B	75.0 /47.2	16 /16	NPTN_HUMAN Neuroplastin
	3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
COMPOUND
385	pdb_id	contact mol		homologue
	pdb_id	a³	description	a⁴	identity[%]⁵	Ncon⁶	description
	6a69[1]	C	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	B	75.0 /47.2	4 /4	NPTN_HUMAN Neuroplastin
	6zr7[1]	G	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	50.0 /40.5	2 /2	DSCAM_HUMAN Down syndrome cell adhesion molecule
	3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
METAL
385	pdb_id	contact mol		homologue
	pdb_id	a³	description	a⁴	identity[%]⁵	Ncon⁶	description
	7daa[1]	D	CD CADMIUM ION[1 atoms]	A	100.0 /98.8	1 /1	BASI_HUMAN Isoform 2 of Basigin
	7daa[1]	E	CD CADMIUM ION[1 atoms]	A	100.0 /98.8	1 /1	BASI_HUMAN Isoform 2 of Basigin
	7daa[1]	F	CD CADMIUM ION[1 atoms]	A	100.0 /98.8	1 /1	BASI_HUMAN Isoform 2 of Basigin
	3i84[4]	C	CL CHLORIDE ION[1 atoms]	B	100.0 /98.7	1 /1	Q54A51_HUMAN Cervical EMMPRIN
	3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
OTHERPOLY
385	pdb_id	contact mol		homologue
	pdb_id	a³	description	a⁴	identity[%]⁵	Ncon⁶	description
	6zr7[1]	B	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galact..	A	0.0 /40.5	1 /8	DSCAM_HUMAN Down syndrome cell adhesion molecule
	6zr7[1]	C	beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-b..	A	0.0 /40.5	6 /6	DSCAM_HUMAN Down syndrome cell adhesion molecule
	3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
HOMO
385	pdb_id	contact mol		homologue
	pdb_id	a³	description	a⁴	identity[%]⁵	Ncon⁶	description
	3qqn[6]	B	BASI_HUMAN Basigin[116 aa]	A	100.0 /98.3	14 /15	BASI_HUMAN Basigin
	3qr2[2]	A	BASI_HUMAN Basigin[117 aa]	A	100.0 /99.1	1 /1	BASI_HUMAN Basigin
	3qr2[4]	B	BASI_HUMAN Basigin[116 aa]	A	100.0 /99.1	7 /7	BASI_HUMAN Basigin
	3qr2[2]	B	BASI_HUMAN Basigin[116 aa]	B	100.0 /99.1	7 /7	BASI_HUMAN Basigin
	3i84[6]	A	Q54A51_HUMAN Cervical EMMPRIN[79 aa]	A	100.0 /98.7	7 /7	Q54A51_HUMAN Cervical EMMPRIN
	3i84[4]	B	Q54A51_HUMAN Cervical EMMPRIN[85 aa]	A	100.0 /98.7	36 /36	Q54A51_HUMAN Cervical EMMPRIN
	3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
PRECIPITANT
385	pdb_id	contact mol		homologue
	pdb_id	a³	description	a⁴	identity[%]⁵	Ncon⁶	description
	3b5h[1]	E	ACT ACETATE ION[4 atoms]	D	100.0 /100.0	2 /2	Q54A51_HUMAN Cervical EMMPRIN
	3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

Contact Molecules for Homologous Proteins

Summary Bars[40 %]

UniProt Feature Tables [P35613(BASI_HUMAN)]