Contact Molecules for Homologous Proteins

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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
18767 967 294 P15144(AMPN_HUMAN) RecName: Full=Aminopeptidase N ; Short=AP-N; Short=hAPN; EC=3.4.11.2 ;AltName: Full=Alanyl aminopeptidase;AltName: Full=Aminopeptidase M; Short=AP-M;AltName: Full=Microsomal aminopeptidase;AltName: Full=Myeloid plasma membrane glycoprotein CD13;AltName: Full=gp150;AltName: CD_antigen=CD13;
QUERYSEQ 
MAKGFYISKSLGILGILLGVAAVCTIIALSVVYSQEKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDI
DKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLI
RIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALA
SSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDY
WLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQ
YSEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSN
LIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWFTENSK
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [P15144(AMPN_HUMAN)]

967
region name description
2-967 CHAIN /note="Aminopeptidase N" /id="PRO_0000095081"
2-8 TOPO_DOM /note="Cytoplasmic"
9-32 TRANSMEM /note="Helical; Signal-anchor for type II membrane protein"
33-967 TOPO_DOM /note="Extracellular"
33-68 REGION /note="Cytosolic Ser/Thr-rich junction"
40-62 REGION /note="Disordered"
69-967 REGION /note="Metalloprotease"
288-295 REGION /note="Necessary and sufficient to mediate interaction with HCoV-229E" ECO:0000269|PubMed:8887485"
389-389 ACT_SITE /note="Proton acceptor" ECO:0000269|PubMed:22932899"
352-356 BINDING /ligand="substrate"
388-388 BINDING /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_note="catalytic" ECO:0007744|PDB:4FYQ, ECO:0007744|PDB:4FYR, ECO:0007744|PDB:4FYT"
392-392 BINDING /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_note="catalytic" ECO:0007744|PDB:4FYQ, ECO:0007744|PDB:4FYR, ECO:0007744|PDB:4FYT"
411-411 BINDING /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_note="catalytic" ECO:0007744|PDB:4FYQ, ECO:0007744|PDB:4FYR, ECO:0007744|PDB:4FYT"
1-967 DISORDER predicted by DISOPRED

MONOMER
967
pdb_id a1 identity[%]2 description
5lhd C 100.0 AMPN_HUMAN Aminopeptidase N
5lhd B 100.0 AMPN_HUMAN Aminopeptidase N
5lhd D 100.0 AMPN_HUMAN Aminopeptidase N
4fyr A 100.0 AMPN_HUMAN Aminopeptidase N
4fys A 100.0 AMPN_HUMAN Aminopeptidase N
4fyt A 100.0 AMPN_HUMAN Aminopeptidase N
5lhd A 100.0 AMPN_HUMAN Aminopeptidase N
6u7e A 100.0 AMPN_HUMAN Aminopeptidase N
6u7e B 100.0 AMPN_HUMAN Aminopeptidase N
6u7g B 100.0 AMPN_HUMAN Aminopeptidase N
6u7g A 100.0 AMPN_HUMAN Aminopeptidase N
6u7f B 100.0 AMPN_HUMAN Aminopeptidase N
6u7f A 100.0 AMPN_HUMAN Aminopeptidase N
7vpq C 100.0 AMPN_HUMAN Aminopeptidase N
7vpq A 100.0 AMPN_HUMAN Aminopeptidase N
7vpq E 100.0 AMPN_HUMAN Aminopeptidase N
4fyq A 100.0 AMPN_HUMAN Aminopeptidase N
6atk A 100.0 AMPN_HUMAN Aminopeptidase N
6atk B 100.0 AMPN_HUMAN Aminopeptidase N
6atk C 100.0 AMPN_HUMAN Aminopeptidase N
5z65 A 79.8 K7GMF9_PIG Aminopeptidase
6bv2 A 79.8 AMPN_PIG Aminopeptidase N
4fke A 79.8 AMPN_PIG Aminopeptidase N
6bv0 A 79.8 AMPN_PIG Aminopeptidase N
6buy A 79.8 AMPN_PIG Aminopeptidase N
6bv4 A 79.8 AMPN_PIG Aminopeptidase N
6bv3 A 79.8 AMPN_PIG Aminopeptidase N
6bv1 A 79.8 AMPN_PIG Aminopeptidase N
4ou3 A 79.8 AMPN_PIG Aminopeptidase N
4fkk A 79.8 AMPN_PIG Aminopeptidase N
4fkh A 79.8 AMPN_PIG Aminopeptidase N
4hom A 79.8 AMPN_PIG Aminopeptidase N
4nz8 A 79.7 AMPN_PIG Aminopeptidase N
7vpp A 79.8 K7GMF9_PIG Aminopeptidase
5lds A 79.8 AMPN_PIG Aminopeptidase N
4naq A 79.6 AMPN_PIG Aminopeptidase N
5lds C 79.8 AMPN_PIG Aminopeptidase N
5lds B 79.8 AMPN_PIG Aminopeptidase N
5lds D 79.8 AMPN_PIG Aminopeptidase N
4f5c A 79.7 AMPN_PIG Aminopeptidase N
7vpp C 79.9 K7GMF9_PIG Aminopeptidase
4f5c B 79.8 AMPN_PIG Aminopeptidase N
5lg6 A 79.9 AMPN_PIG Aminopeptidase N
5lg6 B 79.8 AMPN_PIG Aminopeptidase N
7u0l A 78.6 AMPN_CANLF Aminopeptidase N
4kxb A 37.9 AMPE_HUMAN Glutamyl aminopeptidase
4kxd A 37.9 AMPE_HUMAN Glutamyl aminopeptidase
4kxa A 37.9 AMPE_HUMAN Glutamyl aminopeptidase
4kx7 A 37.9 AMPE_HUMAN Glutamyl aminopeptidase
4kxc A 37.9 AMPE_HUMAN Glutamyl aminopeptidase
4kx8 A 37.9 AMPE_HUMAN Glutamyl aminopeptidase
4kx9 A 37.9 AMPE_HUMAN Glutamyl aminopeptidase
7z28 A 36.8 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6t6r A 36.5 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p O 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p N 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p A 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p H 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p C 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p B 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p U 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p R 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p Q 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p P 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p G 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p T 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p M 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p L 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p K 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p J 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p F 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p D 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p V 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p S 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p I 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6m8p E 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6q4r A 36.9 ERAP1_HUMAN ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1,Endoplasmic reticulum aminopeptidase 1
6rqx A 37.1 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
2yd0 A 37.5 ERAP1_HUMAN ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1
6ryf A 36.9 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6mgq B 37.0 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
6mgq A 36.6 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
4p8q A 36.7 LCAP_HUMAN Leucyl-cystinyl aminopeptidase
4pj6 A 36.7 LCAP_HUMAN Leucyl-cystinyl aminopeptidase
5c97 A 36.6 LCAP_HUMAN Leucyl-cystinyl aminopeptidase
5mj6 B 36.9 LCAP_HUMAN Leucyl-cystinyl aminopeptidase
8cgp B 36.6 LCAP_HUMAN Leucyl-cystinyl aminopeptidase, pregnancy serum form
5mj6 A 36.9 LCAP_HUMAN Leucyl-cystinyl aminopeptidase
8cgp A 36.8 LCAP_HUMAN Leucyl-cystinyl aminopeptidase, pregnancy serum form
4z7i B 36.9 LCAP_HUMAN Leucyl-cystinyl aminopeptidase
4z7i A 36.7 LCAP_HUMAN Leucyl-cystinyl aminopeptidase
7zyf B 36.7 LCAP_HUMAN Leucyl-cystinyl aminopeptidase, pregnancy serum form
6ydx B 36.9 LCAP_HUMAN Leucyl-cystinyl aminopeptidase
7zyf A 36.8 LCAP_HUMAN Leucyl-cystinyl aminopeptidase, pregnancy serum form
6ydx A 37.0 LCAP_HUMAN Leucyl-cystinyl aminopeptidase
8cgw A 36.6 LCAP_HUMAN Leucyl-cystinyl aminopeptidase, pregnancy serum form
8cgw B 36.5 LCAP_HUMAN Leucyl-cystinyl aminopeptidase, pregnancy serum form
7p7p A 36.9 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
5j6s A 36.8 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
6ea4 A 37.2 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
6ea4 B 37.6 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
7pfs A 36.7 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
7nsk A 36.8 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
5ab0 A 36.8 ERAP2_HUMAN ENDOPLASMATIC RETICULUM AMINOPEPTIDASE 2
7nup A 36.7 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
7sh0 A 37.0 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
7nup B 36.7 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
5c97 B 36.5 LCAP_HUMAN Leucyl-cystinyl aminopeptidase
4pj6 B 36.5 LCAP_HUMAN Leucyl-cystinyl aminopeptidase
4p8q B 36.5 LCAP_HUMAN Leucyl-cystinyl aminopeptidase
5ab0 B 37.2 ERAP2_HUMAN ENDOPLASMATIC RETICULUM AMINOPEPTIDASE 2
7nsk B 37.2 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
5k1v A 37.0 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
6mgq C 36.8 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
7nup D 37.2 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
5j6s B 37.2 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
7nup C 37.2 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
3se6 B 37.4 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
3se6 A 37.2 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
5ab2 A 36.6 ERAP2_HUMAN ENDOPLASMIC RETICULUM AMINOPEPTIDASE 2
5ab2 B 37.0 ERAP2_HUMAN ENDOPLASMIC RETICULUM AMINOPEPTIDASE 2
5cu5 A 37.0 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
5cu5 B 37.1 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
4jbs A 37.1 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
4e36 A 37.1 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
4e36 B 37.3 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
4jbs B 37.3 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
7p7p B 37.2 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
8sw0 A 35.2 PSA_HUMAN Puromycin-sensitive aminopeptidase
8sw1 A 35.2 PSA_HUMAN Puromycin-sensitive aminopeptidase
7pfs B 37.3 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
5k1v B 37.5 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
7sh0 B 37.7 ERAP2_HUMAN Endoplasmic reticulum aminopeptidase 2
3mdj B 36.3 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
3mdj C 36.8 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
3mdj A 36.8 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
3qnf B 37.0 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
3qnf C 37.5 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
4wz9 A 36.9 Q7Q2T8_ANOGA AGAP004809-PA
4wz9 B 36.9 Q7Q2T8_ANOGA AGAP004809-PA
3qnf A 40.4 ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1
3q7j B 37.6 TRF3_THEAC Tricorn protease-interacting factor F3
3q7j A 37.6 TRF3_THEAC Tricorn protease-interacting factor F3
1z5h B 37.1 TRF3_THEAC Tricorn protease interacting factor F3
1z5h A 37.1 TRF3_THEAC Tricorn protease interacting factor F3
1z1w A 37.1 TRF3_THEAC Tricorn protease interacting factor F3
7v9o A 37.3 A4F9D7_SACEN Alanine aminopeptidase
7v9q A 37.3 A4F9D7_SACEN Alanine aminopeptidase
7v9n A 37.3 A4F9D7_SACEN Alanine aminopeptidase
7v9p B 37.2 A4F9D7_SACEN Alanine aminopeptidase
7v9p A 37.3 A4F9D7_SACEN Alanine aminopeptidase
5dll A 30.3 Q5NE65_FRATT Aminopeptidase N
5ni6 A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
7kze C 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
5nia A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
5nid A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3chq A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
1gw6 A 30.1 LKHA_HUMAN LEUKOTRIENE A-4 HYDROLASE
3fun A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fuj A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fud A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3ftz A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fty A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3ftu A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fu5 A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fh5 A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fu6 A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fu3 A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
4r7l A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
5n3w A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
7kze A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
5aen A 30.1 LKHA4_HUMAN LEUKOTRIENE A-4 HYDROLASE
3u9w A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
7kze B 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
6o5h C 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
6o5h B 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3chp A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
7llq C 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
7llq B 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
7llq A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fuk A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
4ms6 A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
4mkt A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
6enc A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fum A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3ful A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
5nie B 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fui A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
6o5h A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
4dpr A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fuh A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fuf A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3ftv A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fhe A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fh8 A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3ftx A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fue A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fu0 A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3ftw A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fts A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
3fh7 A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
4l2l A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
8qow A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
7auz A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
6end A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
7av2 A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
8qq4 A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
8qpn A 30.1 LKHA4_HUMAN Leukotriene A-4 hydrolase
8rx9 A 30.1