Contact Molecules for Homologous Proteins


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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
3661393 274 12 P59632(AP3A_SARS) RecName: Full=ORF3a protein;AltName: Full=Accessory protein 3a;AltName: Full=Protein 3a;AltName: Full=Protein U274;AltName: Full=Protein X1;
QUERYSEQ
MDLFMRFFTLGSITAQPVKIDNASPASTVHATATIPLQASLPFGWLVIGVAFLAVFQSATKIIALNKRWQLALYKGFQFICNLLLLFVTIYSHLLLVAAGMEAQFLYLYALIYFLQCINACRIIMRCWLCWKCKSKNPLLYDANYFVCWH
THNYDYCIPYNSVTDTIVVTEGDGISTPKLKEDYQIGGYSEDRHSGVKDYVVVHGYFTEVYYQLESTQITTDTGIENATFFIFNKLVKDPPNVQIHTIDGSSGVANPAMDPIYDEPTTTTSVPL
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [P59632(AP3A_SARS)]

274
region name description
1-274 CHAIN /note="ORF3a protein" /id="PRO_0000106131"
1-34 TOPO_DOM /note="Extracellular"
35-55 TRANSMEM /note="Helical"
56-78 TOPO_DOM /note="Cytoplasmic"
79-99 TRANSMEM /note="Helical"
100-104 TOPO_DOM /note="Extracellular"
105-125 TRANSMEM /note="Helical"
126-274 TOPO_DOM /note="Cytoplasmic"
33-141 DOMAIN /note="CoV 3a-like viroporin TM"
145-237 DOMAIN /note="CoV 3a-like viroporin CD"
1-274 DISORDER predicted by DISOPRED

MONOMER
274
pdb_id a1 identity[%]2 description
8eqs B 100.0 AP3A_SARS ORF3a protein
8eqs A 100.0 AP3A_SARS ORF3a protein
6xdc A 76.6 AP3A_SARS2 ORF3a protein
6xdc B 76.6 AP3A_SARS2 ORF3a protein
7kjr A 76.6 AP3A_SARS2 ORF3a protein
7kjr B 76.6 AP3A_SARS2 ORF3a protein
8equ B 76.4 AP3A_SARS2 ORF3a protein
8equ A 76.4 AP3A_SARS2 ORF3a protein
8eqj B 76.4 AP3A_SARS2 ORF3a protein
8eqj A 76.4 AP3A_SARS2 ORF3a protein
8eqt B 76.8 AP3A_SARS2 ORF3a protein
8eqt A 76.8 AP3A_SARS2 ORF3a protein
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue.
HETERO
274 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
7kjr C APOA1_HUMAN Apolipoprotein A-I[31 aa] A 83.3
/76.6
6
/6
AP3A_SARS2 ORF3a protein
7kjr D APOA1_HUMAN Apolipoprotein A-I[31 aa] A 83.3
/76.6
6
/6
AP3A_SARS2 ORF3a protein
7kjr C APOA1_HUMAN Apolipoprotein A-I[31 aa] B 80.0
/76.6
5
/5
AP3A_SARS2 ORF3a protein
7kjr D APOA1_HUMAN Apolipoprotein A-I[31 aa] B 83.3
/76.6
6
/6
AP3A_SARS2 ORF3a protein
8eqs C APOA1_HUMAN Apolipoprotein A-I[27 aa] A 100.0
/100.0
3
/3
AP3A_SARS ORF3a protein
8eqs D APOA1_HUMAN Apolipoprotein A-I[27 aa] A 100.0
/100.0
4
/4
AP3A_SARS ORF3a protein
8eqs C APOA1_HUMAN Apolipoprotein A-I[27 aa] B 100.0
/100.0
4
/4
AP3A_SARS ORF3a protein
8eqs D APOA1_HUMAN Apolipoprotein A-I[27 aa] B 100.0
/100.0
3
/3
AP3A_SARS ORF3a protein
8equ C SAP_HUMAN Saposin-A[80 aa] A 85.7
/76.4
7
/7
AP3A_SARS2 ORF3a protein
8equ F SAP_HUMAN Saposin-A[80 aa] A 0.0
/76.4
1
/1
AP3A_SARS2 ORF3a protein
8equ C SAP_HUMAN Saposin-A[80 aa] B 0.0
/76.4
1
/1
AP3A_SARS2 ORF3a protein
8equ F SAP_HUMAN Saposin-A[80 aa] B 100.0
/76.4
5
/5
AP3A_SARS2 ORF3a protein
8equ D Saposin A, polyalanine model[79 aa] A 100.0
/76.4
1
/1
AP3A_SARS2 ORF3a protein
8equ G Saposin A, polyalanine model[79 aa] B 100.0
/76.4
1
/1
AP3A_SARS2 ORF3a protein
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
COMPOUND
274 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
7kjr E PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a..
A 75.0
/76.6
4
/4
AP3A_SARS2 ORF3a protein
7kjr F PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a..
A 75.0
/76.6
4
/4
AP3A_SARS2 ORF3a protein
7kjr E PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a..
B 75.0
/76.6
4
/4
AP3A_SARS2 ORF3a protein
7kjr F PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a..
B 75.0
/76.6
4
/4
AP3A_SARS2 ORF3a protein
8eqj C PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a..
A 83.3
/76.4
6
/6
AP3A_SARS2 ORF3a protein
8eqj D PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[22 a..
A 85.7
/76.4
7
/7
AP3A_SARS2 ORF3a protein
8eqj E PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a..
A 66.7
/76.4
3
/3
AP3A_SARS2 ORF3a protein
8eqj C PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a..
B 66.7
/76.4
3
/3
AP3A_SARS2 ORF3a protein
8eqj E PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a..
B 83.3
/76.4
6
/6
AP3A_SARS2 ORF3a protein
8eqj F PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[22 a..
B 85.7
/76.4
7
/7
AP3A_SARS2 ORF3a protein
8eqs E PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[25 a..
A 100.0
/100.0
4
/4
AP3A_SARS ORF3a protein
8eqs F PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[25 a..
A 100.0
/100.0
4
/4
AP3A_SARS ORF3a protein
8eqs E PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[25 a..
B 100.0
/100.0
4
/4
AP3A_SARS ORF3a protein
8eqs F PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[25 a..
B 100.0
/100.0
4
/4
AP3A_SARS ORF3a protein
8eqt C PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[22 a..
A 85.7
/76.8
7
/7
AP3A_SARS2 ORF3a protein
8eqt D PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[19 a..
A 75.0
/76.8
4
/4
AP3A_SARS2 ORF3a protein
8eqt E PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[19 a..
A 100.0
/76.8
2
/2
AP3A_SARS2 ORF3a protein
8eqt D PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[19 a..
B 100.0
/76.8
2
/2
AP3A_SARS2 ORF3a protein
8eqt E PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[19 a..
B 75.0
/76.8
4
/4
AP3A_SARS2 ORF3a protein
8eqt F PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[22 a..
B 85.7
/76.8
7
/7
AP3A_SARS2 ORF3a protein
8equ I PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a..
A 60.0
/76.4
5
/5
AP3A_SARS2 ORF3a protein
8equ J PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a..
A 100.0
/76.4
1
/1
AP3A_SARS2 ORF3a protein
8equ I PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a..
B 100.0
/76.4
1
/1
AP3A_SARS2 ORF3a protein
8equ J PEE
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine[23 a..
B 60.0
/76.4
5
/5
AP3A_SARS2 ORF3a protein
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
HOMO
274 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
8eqs B AP3A_SARS ORF3a protein[192 aa] A 100.0
/100.0
48
/48
AP3A_SARS ORF3a protein
8eqs A AP3A_SARS ORF3a protein[192 aa] B 100.0
/100.0
48
/48
AP3A_SARS ORF3a protein
6xdc B AP3A_SARS2 ORF3a protein[193 aa] A 88.1
/76.6
42
/42
AP3A_SARS2 ORF3a protein
6xdc A AP3A_SARS2 ORF3a protein[193 aa] B 88.4
/76.6
43
/43
AP3A_SARS2 ORF3a protein
7kjr B AP3A_SARS2 ORF3a protein[193 aa] A 87.0
/76.6
54
/54
AP3A_SARS2 ORF3a protein
7kjr A AP3A_SARS2 ORF3a protein[193 aa] B 85.5
/76.6
55
/55
AP3A_SARS2 ORF3a protein
8eqj B AP3A_SARS2 ORF3a protein[192 aa] A 79.2
/76.4
48
/48
AP3A_SARS2 ORF3a protein
8eqj A AP3A_SARS2 ORF3a protein[192 aa] B 79.2
/76.4
48
/48
AP3A_SARS2 ORF3a protein
8eqt B AP3A_SARS2 ORF3a protein[191 aa] A 88.6
/76.8
44
/44
AP3A_SARS2 ORF3a protein
8eqt A AP3A_SARS2 ORF3a protein[191 aa] B 88.6
/76.8
44
/44
AP3A_SARS2 ORF3a protein
8equ B AP3A_SARS2 ORF3a protein[191 aa] A 83.3
/76.4
48
/48
AP3A_SARS2 ORF3a protein
8equ A AP3A_SARS2 ORF3a protein[191 aa] B 81.6
/76.4
49
/49
AP3A_SARS2 ORF3a protein
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.