Contact Molecules for Homologous Proteins


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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
3207930 164 29 P01185(NEU2_HUMAN) RecName: Full=Vasopressin-neurophysin 2-copeptin;AltName: Full=AVP-NPII;Contains: RecName: Full=Arg-vasopressin; AltName: Full=Arginine-vasopressin;Contains: RecName: Full=Neurophysin 2; AltName: Full=Neurophysin-II;Contains: RecName: Full=Copeptin;Flags: Precursor;
QUERYSEQ
MPDTMLPACFLGLLAFSSACYFQNCPRGGKRAMSDLELRQCLPCGPGGKGRCFGPSICCADELGCFVGTAEALRCQEENYLPSPCQSGQKACGSGGRCAAFGVCCNDESCVTEPECREGFHRRARASDRSNATQLDGPAGALLLRLVQLA
GAPEPFEPAQPDAY
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [P01185(NEU2_HUMAN)]

164
region name description
1-19 SIGNAL
20-28 PEPTIDE /note="Arg-vasopressin" /id="PRO_0000020515"
32-124 CHAIN /note="Neurophysin 2" /id="PRO_0000020516"
126-164 PEPTIDE /note="Copeptin" /id="PRO_0000020517"
1-164 DISORDER predicted by DISOPRED

MONOMER
164
pdb_id a1 identity[%]2 description
2bn2 A 95.3 NEU2_BOVIN NEUROPHYSIN II
1npo A 95.1 NEU2_BOVIN NEUROPHYSIN II
1jk6 B 95.0 NEU2_BOVIN NEUROPHYSIN 2
1jk6 A 95.0 NEU2_BOVIN NEUROPHYSIN 2
1jk4 A 94.9 NEU2_BOVIN NEUROPHYSIN 2
2bn2 D 94.9 NEU2_BOVIN NEUROPHYSIN II
2bn2 C 94.9 NEU2_BOVIN NEUROPHYSIN II
2bn2 B 94.9 NEU2_BOVIN NEUROPHYSIN II
1npo C 93.7 NEU2_BOVIN NEUROPHYSIN II
2lbh B 80.0 NEU1_BOVIN Neurophysin 1
2lbh A 80.0 NEU1_BOVIN Neurophysin 1
1l5d A 80.0 NEU1_BOVIN NEUROPHYSIN 1
2lbn A 80.0 NEU1_BOVIN Neurophysin 1
1l5c A 80.0 NEU1_BOVIN NEUROPHYSIN 1
2hnw E 82.3 NEU1_BOVIN Oxytocin-neurophysin 1
2hnw D 82.3 NEU1_BOVIN Oxytocin-neurophysin 1
2hnw C 82.3 NEU1_BOVIN Oxytocin-neurophysin 1
2hnw B 82.3 NEU1_BOVIN Oxytocin-neurophysin 1
2hnw A 82.3 NEU1_BOVIN Oxytocin-neurophysin 1
2hnu B 82.3 NEU1_BOVIN Oxytocin-neurophysin 1
2hnu D 82.3 NEU1_BOVIN Oxytocin-neurophysin 1
2hnu C 82.3 NEU1_BOVIN Oxytocin-neurophysin 1
2hnu E 82.3 NEU1_BOVIN Oxytocin-neurophysin 1
2hnu A 82.3 NEU1_BOVIN Oxytocin-neurophysin 1
2hnv C 81.0 NEU1_BOVIN Oxytocin-neurophysin 1
2hnv B 81.0 NEU1_BOVIN Oxytocin-neurophysin 1
2hnv E 81.0 NEU1_BOVIN Oxytocin-neurophysin 1
2hnv D 81.0 NEU1_BOVIN Oxytocin-neurophysin 1
2hnv A 81.0 NEU1_BOVIN Oxytocin-neurophysin 1
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue.
HETERO
164 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1jk4 B Lys Vasopressin[6 aa] A 100.0
/94.9
14
/14
NEU2_BOVIN NEUROPHYSIN 2
1jk4 B Lys Vasopressin[6 aa] A 100.0
/94.9
14
/14
NEU2_BOVIN NEUROPHYSIN 2
1npo B OXYTOCIN[9 aa] A 100.0
/95.1
16
/16
NEU2_BOVIN NEUROPHYSIN II
1npo B OXYTOCIN[9 aa] A 100.0
/95.1
16
/16
NEU2_BOVIN NEUROPHYSIN II
1npo B OXYTOCIN[9 aa] C 100.0
/93.7
5
/5
NEU2_BOVIN NEUROPHYSIN II
1npo B OXYTOCIN[9 aa] C 100.0
/93.7
5
/5
NEU2_BOVIN NEUROPHYSIN II
1npo D OXYTOCIN[9 aa] C 100.0
/93.7
16
/16
NEU2_BOVIN NEUROPHYSIN II
1npo D OXYTOCIN[9 aa] C 100.0
/93.7
16
/16
NEU2_BOVIN NEUROPHYSIN II
1npo D OXYTOCIN[9 aa] C 100.0
/93.7
16
/16
NEU2_BOVIN NEUROPHYSIN II
1npo C NEU2_BOVIN NEUROPHYSIN II[79 aa] A 92.3
/95.1
13
/13
NEU2_BOVIN NEUROPHYSIN II
1npo C NEU2_BOVIN NEUROPHYSIN II[79 aa] A 100.0
/95.1
4
/4
NEU2_BOVIN NEUROPHYSIN II
1npo C NEU2_BOVIN NEUROPHYSIN II[79 aa] A 100.0
/95.1
2
/2
NEU2_BOVIN NEUROPHYSIN II
1npo C NEU2_BOVIN NEUROPHYSIN II[79 aa] A 100.0
/95.1
2
/2
NEU2_BOVIN NEUROPHYSIN II
1npo C NEU2_BOVIN NEUROPHYSIN II[79 aa] A 100.0
/95.1
4
/4
NEU2_BOVIN NEUROPHYSIN II
1npo A NEU2_BOVIN NEUROPHYSIN II[81 aa] C 92.3
/93.7
13
/13
NEU2_BOVIN NEUROPHYSIN II
1npo A NEU2_BOVIN NEUROPHYSIN II[81 aa] C 100.0
/93.7
4
/4
NEU2_BOVIN NEUROPHYSIN II
1npo A NEU2_BOVIN NEUROPHYSIN II[81 aa] C 100.0
/93.7
4
/4
NEU2_BOVIN NEUROPHYSIN II
1npo A NEU2_BOVIN NEUROPHYSIN II[81 aa] C 100.0
/93.7
4
/4
NEU2_BOVIN NEUROPHYSIN II
1npo A NEU2_BOVIN NEUROPHYSIN II[81 aa] C 100.0
/93.7
4
/4
NEU2_BOVIN NEUROPHYSIN II
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
COMPOUND
164 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
2bn2 E PHE
PHENYLALANINE[11 atoms]
A 100.0
/95.3
7
/7
NEU2_BOVIN NEUROPHYSIN II
2bn2 G PHE
PHENYLALANINE[11 atoms]
B 100.0
/94.9
6
/6
NEU2_BOVIN NEUROPHYSIN II
2bn2 I PHE
PHENYLALANINE[11 atoms]
C 100.0
/94.9
6
/6
NEU2_BOVIN NEUROPHYSIN II
2bn2 K PHE
PHENYLALANINE[11 atoms]
D 100.0
/94.9
6
/6
NEU2_BOVIN NEUROPHYSIN II
2hnu F PHE
PHENYLALANINE[11 atoms]
A 100.0
/82.3
7
/7
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu H PHE
PHENYLALANINE[11 atoms]
B 100.0
/82.3
6
/6
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu J PHE
PHENYLALANINE[11 atoms]
C 100.0
/82.3
7
/7
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu L PHE
PHENYLALANINE[11 atoms]
D 100.0
/82.3
6
/6
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu N PHE
PHENYLALANINE[11 atoms]
E 100.0
/82.3
7
/7
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu N PHE
PHENYLALANINE[11 atoms]
E 100.0
/82.3
7
/7
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv F PHE
PHENYLALANINE[11 atoms]
A 100.0
/81.0
7
/7
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv H PHE
PHENYLALANINE[11 atoms]
B 100.0
/81.0
8
/8
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv J PHE
PHENYLALANINE[11 atoms]
C 100.0
/81.0
7
/7
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv L PHE
PHENYLALANINE[11 atoms]
D 100.0
/81.0
6
/6
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv N PHE
PHENYLALANINE[11 atoms]
E 100.0
/81.0
6
/6
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv N PHE
PHENYLALANINE[11 atoms]
E 100.0
/81.0
6
/6
NEU1_BOVIN Oxytocin-neurophysin 1
2bn2 F TYR
TYROSINE[12 atoms]
A 100.0
/95.3
8
/8
NEU2_BOVIN NEUROPHYSIN II
2bn2 H TYR
TYROSINE[12 atoms]
B 100.0
/94.9
8
/8
NEU2_BOVIN NEUROPHYSIN II
2bn2 J TYR
TYROSINE[12 atoms]
C 100.0
/94.9
9
/9
NEU2_BOVIN NEUROPHYSIN II
2bn2 L TYR
TYROSINE[12 atoms]
D 100.0
/94.9
9
/9
NEU2_BOVIN NEUROPHYSIN II
2hnu G TYR
TYROSINE[13 atoms]
A 100.0
/82.3
9
/9
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu I TYR
TYROSINE[13 atoms]
B 100.0
/82.3
9
/9
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu K TYR
TYROSINE[13 atoms]
C 100.0
/82.3
8
/8
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu M TYR
TYROSINE[13 atoms]
D 100.0
/82.3
7
/7
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu O TYR
TYROSINE[13 atoms]
E 100.0
/82.3
9
/9
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu O TYR
TYROSINE[13 atoms]
E 100.0
/82.3
9
/9
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv G TYR
TYROSINE[13 atoms]
A 100.0
/81.0
9
/9
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv I TYR
TYROSINE[13 atoms]
B 100.0
/81.0
9
/9
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv K TYR
TYROSINE[13 atoms]
C 100.0
/81.0
9
/9
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv M TYR
TYROSINE[13 atoms]
D 100.0
/81.0
9
/9
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv O TYR
TYROSINE[13 atoms]
E 100.0
/81.0
9
/9
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv O TYR
TYROSINE[13 atoms]
E 100.0
/81.0
9
/9
NEU1_BOVIN Oxytocin-neurophysin 1
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
METAL
164 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1jk4 C CD
CADMIUM ION[1 atoms]
A 100.0
/94.9
1
/1
NEU2_BOVIN NEUROPHYSIN 2
1jk4 C CD
CADMIUM ION[1 atoms]
A 100.0
/94.9
1
/1
NEU2_BOVIN NEUROPHYSIN 2
1jk4 D CD
CADMIUM ION[1 atoms]
A 100.0
/94.9
1
/1
NEU2_BOVIN NEUROPHYSIN 2
1jk4 D CD
CADMIUM ION[1 atoms]
A 100.0
/94.9
1
/1
NEU2_BOVIN NEUROPHYSIN 2
1jk4 E CD
CADMIUM ION[1 atoms]
A 100.0
/94.9
1
/1
NEU2_BOVIN NEUROPHYSIN 2
1jk4 E CD
CADMIUM ION[1 atoms]
A 100.0
/94.9
1
/1
NEU2_BOVIN NEUROPHYSIN 2
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
HOMO
164 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1jk4 A NEU2_BOVIN NEUROPHYSIN 2[79 aa] A 92.3
/94.9
13
/13
NEU2_BOVIN NEUROPHYSIN 2
1jk4 A NEU2_BOVIN NEUROPHYSIN 2[79 aa] A 92.3
/94.9
13
/13
NEU2_BOVIN NEUROPHYSIN 2
1jk6 B NEU2_BOVIN NEUROPHYSIN 2[80 aa] A 92.9
/95.0
14
/14
NEU2_BOVIN NEUROPHYSIN 2
1jk6 A NEU2_BOVIN NEUROPHYSIN 2[80 aa] B 92.3
/95.0
13
/13
NEU2_BOVIN NEUROPHYSIN 2
1npo A NEU2_BOVIN NEUROPHYSIN II[81 aa] A 100.0
/95.1
7
/7
NEU2_BOVIN NEUROPHYSIN II
1npo A NEU2_BOVIN NEUROPHYSIN II[81 aa] A 100.0
/95.1
7
/7
NEU2_BOVIN NEUROPHYSIN II
2bn2 B NEU2_BOVIN NEUROPHYSIN II[79 aa] A 91.7
/95.3
12
/12
NEU2_BOVIN NEUROPHYSIN II
2bn2 A NEU2_BOVIN NEUROPHYSIN II[85 aa] B 92.9
/94.9
14
/14
NEU2_BOVIN NEUROPHYSIN II
2bn2 D NEU2_BOVIN NEUROPHYSIN II[79 aa] C 92.3
/94.9
13
/13
NEU2_BOVIN NEUROPHYSIN II
2bn2 C NEU2_BOVIN NEUROPHYSIN II[79 aa] D 92.3
/94.9
13
/13
NEU2_BOVIN NEUROPHYSIN II
2hnu B NEU1_BOVIN Oxytocin-neurophysin 1[81 aa] A 66.7
/82.3
15
/15
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu A NEU1_BOVIN Oxytocin-neurophysin 1[81 aa] B 66.7
/82.3
15
/15
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu D NEU1_BOVIN Oxytocin-neurophysin 1[81 aa] C 66.7
/82.3
15
/15
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu C NEU1_BOVIN Oxytocin-neurophysin 1[81 aa] D 60.0
/82.3
15
/15
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu E NEU1_BOVIN Oxytocin-neurophysin 1[81 aa] E 64.3
/82.3
14
/14
NEU1_BOVIN Oxytocin-neurophysin 1
2hnu E NEU1_BOVIN Oxytocin-neurophysin 1[81 aa] E 64.3
/82.3
14
/14
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv B NEU1_BOVIN Oxytocin-neurophysin 1[81 aa] A 66.7
/81.0
15
/15
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv A NEU1_BOVIN Oxytocin-neurophysin 1[81 aa] B 64.3
/81.0
14
/14
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv D NEU1_BOVIN Oxytocin-neurophysin 1[81 aa] C 66.7
/81.0
15
/15
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv C NEU1_BOVIN Oxytocin-neurophysin 1[81 aa] D 64.3
/81.0
14
/14
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv E NEU1_BOVIN Oxytocin-neurophysin 1[81 aa] E 64.3
/81.0
14
/14
NEU1_BOVIN Oxytocin-neurophysin 1
2hnv E NEU1_BOVIN Oxytocin-neurophysin 1[81 aa] E 64.3
/81.0
14
/14
NEU1_BOVIN Oxytocin-neurophysin 1
2hnw B NEU1_BOVIN Oxytocin-neurophysin 1[80 aa] A 66.7
/82.3
15
/15
NEU1_BOVIN Oxytocin-neurophysin 1
2hnw A NEU1_BOVIN Oxytocin-neurophysin 1[80 aa] B 64.3
/82.3
14
/14
NEU1_BOVIN Oxytocin-neurophysin 1
2hnw D NEU1_BOVIN Oxytocin-neurophysin 1[80 aa] C 69.2
/82.3
13
/13
NEU1_BOVIN Oxytocin-neurophysin 1
2hnw C NEU1_BOVIN Oxytocin-neurophysin 1[80 aa] D 64.3
/82.3
14
/14
NEU1_BOVIN Oxytocin-neurophysin 1
2hnw E NEU1_BOVIN Oxytocin-neurophysin 1[80 aa] E 61.5
/82.3
13
/13
NEU1_BOVIN Oxytocin-neurophysin 1
2hnw E NEU1_BOVIN Oxytocin-neurophysin 1[80 aa] E 61.5
/82.3
13
/13
NEU1_BOVIN Oxytocin-neurophysin 1
2lbh B NEU1_BOVIN Neurophysin 1[92 aa] A 66.7
/80.0
15
/15
NEU1_BOVIN Neurophysin 1
2lbh A NEU1_BOVIN Neurophysin 1[92 aa] B 66.7
/80.0
15
/15
NEU1_BOVIN Neurophysin 1
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.