Contact Molecules for Homologous Proteins | ||||
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PID | QueryLength | Homolgous Sequence in PDB | UniProt Query | TITLE |
3177232 | 515 | 12 | P48551(INAR2_HUMAN) | RecName: Full=Interferon alpha/beta receptor 2; Short=IFN-R-2; Short=IFN-alpha binding protein; Short=IFN-alpha/beta receptor 2;AltName: Full=Interferon alpha binding protein;AltName: Full=Type I interferon receptor 2;Flags: Precursor; |
QUERYSEQ |
MLLSQNAFIFRSLNLVLMVYISLVFGISYDSPDYTDESCTFKISLRNFRSILSWELKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRSTHEAYVTVLEGFSGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINV MVKFPSIVEEELQFDLSLVIEEQSEGIVKKHKPEIKGNMSGNFTYIIDKLIPNTNYCVSVYLEHSDEQAVIKSPLKCTLLPPGQESESAESAKIGGIITVFLIALVLTSTIVTLKWIGYICLRNSLPKVLNFHNFLAWPFPNLPPLEAMD MVEVIYINRKKKVWDYNYDDESDSDTEAAPRTSGGGYTMHGLTVRPLGQASATSTESQLIDPESEEEPDLPEVDVELPTMPKDSPQQLELLSGPCERRKSPLQDPFPEEDYSSTEGSGGRITFNVDLNSVFLRVLDDEDSDDLEAPLMLS SHLEEMVDPEDPDNVQSNHLLASGEGTQPTFPSPSSEGLWSEDAPSDQSDTSESDVDLGDGYIMR |
515 | region | name | description |
1-26 | SIGNAL | ||
27-515 | CHAIN | /note="Interferon alpha/beta receptor 2" /id="PRO_0000011006" | |
27-243 | TOPO_DOM | /note="Extracellular" | |
244-264 | TRANSMEM | /note="Helical" | |
265-515 | TOPO_DOM | /note="Cytoplasmic" | |
318-418 | REGION | /note="Disordered" | |
418-444 | REGION | /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" | |
455-515 | REGION | /note="Disordered" | |
466-497 | COMPBIAS | /note="Polar residues" | |
1-515 | DISORDER | predicted by DISOPRED |
MONOMER | |||||||
515 | |||||||
pdb_id | a1 | identity[%]2 | description | ||||
2hym | A | 100.0 | Q15467_HUMAN Soluble IFN alpha/beta receptor | ||||
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue. |
HETERO | |||||||
515 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
2hym[3] | B | IFNA2_HUMAN Interferon alpha-2[165 aa] | A | 100.0 /100.0 |
19 /19 |
Q15467_HUMAN Soluble IFN alpha/beta receptor | |
3s9d[2] | A | IFNA2_HUMAN Interferon alpha-2[127 aa] | B | 100.0 /100.0 |
19 /19 |
INAR2_HUMAN Interferon alpha/beta receptor 2 | |
3s9d[1] | C | IFNA2_HUMAN Interferon alpha-2[116 aa] | D | 100.0 /100.0 |
19 /19 |
INAR2_HUMAN Interferon alpha/beta receptor 2 | |
3se4[1] | B | IFNW1_HUMAN Interferon omega-1[143 aa] | C | 100.0 /100.0 |
18 /18 |
INAR2_HUMAN Interferon alpha/beta receptor 2 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
METAL | |||||||
515 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
3s8w[2] | D |
CL
CHLORIDE ION[1 atoms] |
A | 100.0 /100.0 |
1 /1 |
INAR2_HUMAN Interferon alpha/beta receptor 2 | |
3s8w[1] | E |
CL
CHLORIDE ION[1 atoms] |
C | 100.0 /100.0 |
3 /3 |
INAR2_HUMAN Interferon alpha/beta receptor 2 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. |