Contact Molecules for Homologous Proteins | ||||
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PID | QueryLength | Homolgous Sequence in PDB | UniProt Query | TITLE |
27558 | 918 | 30 | P40189(IL6RB_HUMAN) | RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor; |
QUERYSEQ |
MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESS QNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEG MPKSYLPQTVRQGGYMPQ |
918 | region | name | description |
1-22 | SIGNAL | ||
23-918 | CHAIN | /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899" | |
23-619 | TOPO_DOM | /note="Extracellular" | |
620-641 | TRANSMEM | /note="Helical" | |
642-918 | TOPO_DOM | /note="Cytoplasmic" | |
26-120 | DOMAIN | /note="Ig-like C2-type" | |
125-216 | DOMAIN | /note="Fibronectin type-III 1" | |
224-324 | DOMAIN | /note="Fibronectin type-III 2" | |
329-424 | DOMAIN | /note="Fibronectin type-III 3" | |
426-517 | DOMAIN | /note="Fibronectin type-III 4" | |
518-613 | DOMAIN | /note="Fibronectin type-III 5" | |
660-681 | REGION | /note="Disordered" | |
722-758 | REGION | /note="Disordered" | |
724-758 | COMPBIAS | /note="Polar residues" | |
1-918 | DISORDER | predicted by DISOPRED |
MONOMER | |||||||
918 | |||||||
pdb_id | a1 | identity[%]2 | description | ||||
8d82 | C | 100.0 | IL6RB_HUMAN Interleukin-6 receptor subunit beta | ||||
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue. |
HETERO | |||||||
918 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
1i1r[2] | B | Q98823_HHV8 VIRAL IL-6[167 aa] | A | 100.0 /100.0 |
11 /11 |
IL6RB_HUMAN INTERLEUKIN-6 RECEPTOR BETA CHAIN | |
1i1r[2] | B | Q98823_HHV8 VIRAL IL-6[167 aa] | A | 100.0 /100.0 |
18 /18 |
IL6RB_HUMAN INTERLEUKIN-6 RECEPTOR BETA CHAIN | |
1p9m[4] | B | IL6_HUMAN Interleukin-6[163 aa] | A | 100.0 /100.0 |
12 /12 |
IL6RB_HUMAN Interleukin-6 receptor beta chain | |
1p9m[4] | B | IL6_HUMAN Interleukin-6[163 aa] | A | 100.0 /100.0 |
16 /16 |
IL6RB_HUMAN Interleukin-6 receptor beta chain | |
1p9m[2] | C | IL6RA_HUMAN Interleukin-6 receptor alpha chain[201 aa] | A | 100.0 /100.0 |
11 /11 |
IL6RB_HUMAN Interleukin-6 receptor beta chain | |
1p9m[2] | C | IL6RA_HUMAN Interleukin-6 receptor alpha chain[201 aa] | A | 100.0 /100.0 |
4 /4 |
IL6RB_HUMAN Interleukin-6 receptor beta chain | |
1pvh[2] | B | LIF_HUMAN Leukemia inhibitory factor[169 aa] | A | 100.0 /100.0 |
13 /13 |
IL6RB_HUMAN Interleukin-6 receptor beta chain | |
8d6a[1] | A | LIF_HUMAN Leukemia inhibitory factor[169 aa] | B | 100.0 /100.0 |
10 /10 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
7u7n[2] | C | IL27B_HUMAN Interleukin-27 subunit beta[200 aa] | B | 100.0 /100.0 |
4 /4 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
7u7n[2] | D | IL27A_HUMAN Interleukin-27 subunit alpha[191 aa] | B | 100.0 /100.0 |
12 /12 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d74[1] | B | CNTF_HUMAN Ciliary neurotrophic factor[174 aa] | A | 100.0 /100.0 |
12 /12 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d74[2] | C | CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha.. | A | 100.0 /100.0 |
11 /11 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d7r[1] | A | CLCF1_HUMAN Cardiotrophin-like cytokine factor 1[178 aa] | D | 100.0 /100.0 |
5 /5 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d82[2] | A | IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha[296 a.. | C | 100.0 /100.0 |
11 /11 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d82[2] | D | IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha[296 a.. | C | 100.0 /100.0 |
4 /4 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8dps[10] | B | IL11_HUMAN Interleukin-11[165 aa] | A | 100.0 /100.0 |
10 /10 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8dps[10] | E | IL11_HUMAN Interleukin-11[165 aa] | A | 100.0 /100.0 |
13 /13 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8dps[2] | C | I11RA_HUMAN Interleukin-11 receptor subunit alpha[200 aa] | A | 100.0 /100.0 |
11 /11 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8dps[2] | F | I11RA_HUMAN Interleukin-11 receptor subunit alpha[200 aa] | A | 100.0 /100.0 |
2 /2 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8dpt[8] | C | I11RA_HUMAN Interleukin-11 receptor subunit alpha[294 aa] | A | 100.0 /100.0 |
12 /12 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8dpt[8] | F | I11RA_HUMAN Interleukin-11 receptor subunit alpha[294 aa] | A | 100.0 /100.0 |
4 /4 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8upa[2] | A | De novo designed IL-6 mimetic[56 aa] | B | 100.0 /100.0 |
16 /16 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
COMPOUND | |||||||
918 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
7u7n[5] | K |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
B | 100.0 /100.0 |
2 /2 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
7u7n[17] | L |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
B | 100.0 /100.0 |
4 /4 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d6a[4] | J |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
B | 100.0 /100.0 |
3 /3 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d6a[5] | L |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
B | 100.0 /100.0 |
2 /2 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d6a[5] | M |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
B | 100.0 /100.0 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d82[3] | T |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
C | 100.0 /100.0 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d82[2] | Y |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
C | 100.0 /100.0 |
3 /3 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8dps[10] | K |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 100.0 /100.0 |
2 /2 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8upa[2] | E |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
B | 100.0 /100.0 |
2 /2 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8upa[2] | F |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
B | 100.0 /100.0 |
3 /3 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
METAL | |||||||
918 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
1pvh[1] | E |
IOD
IODIDE ION[1 atoms] |
A | 100.0 /100.0 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor beta chain | |
3l5i[1] | O |
CL
CHLORIDE ION[1 atoms] |
A | 100.0 /100.0 |
4 /4 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[1] | Q |
CL
CHLORIDE ION[1 atoms] |
A | 100.0 /100.0 |
2 /2 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[3] | T |
CL
CHLORIDE ION[1 atoms] |
A | 100.0 /100.0 |
4 /4 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5j[1] | F |
CL
CHLORIDE ION[1 atoms] |
B | 100.0 /100.0 |
5 /5 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5j[1] | G |
CL
CHLORIDE ION[1 atoms] |
B | 100.0 /100.0 |
4 /4 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
OTHERPOLY | |||||||
918 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
3l5h[4] | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | A | 100.0 /100.0 |
2 /2 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5h[11] | D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | A | 100.0 /100.0 |
3 /3 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5h[1] | H | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | A | 100.0 /100.0 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
7u7n[4] | E | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | B | 100.0 /100.0 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d82[3] | H | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | C | 100.0 /100.0 |
4 /4 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d82[2] | I | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | C | 100.0 /100.0 |
6 /6 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d82[2] | K | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | C | 100.0 /100.0 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5h[1] | C | beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1.. | A | 100.0 /100.0 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5h[1] | F | beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1.. | A | 100.0 /100.0 |
5 /5 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5h[1] | E | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | A | 100.0 /100.0 |
3 /3 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
7u7n[1] | G | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | B | 100.0 /100.0 |
2 /2 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
7u7n[1] | H | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | B | 100.0 /100.0 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5h[1] | G | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-bet.. | A | 100.0 /100.0 |
2 /2 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
7u7n[1] | F | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(.. | B | 100.0 /100.0 |
3 /3 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
HOMO | |||||||
918 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
1bqu[1] | B | IL6RB_HUMAN PROTEIN (GP130)[215 aa] | A | 100.0 /99.5 |
9 /9 |
IL6RB_HUMAN PROTEIN (GP130) | |
1bqu[1] | A | IL6RB_HUMAN PROTEIN (GP130)[208 aa] | B | 100.0 /99.5 |
11 /11 |
IL6RB_HUMAN PROTEIN (GP130) | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
PRECIPITANT | |||||||
918 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
1bqu[3] | C |
SO4
SULFATE ION[5 atoms] |
A | 100.0 /99.5 |
4 /4 |
IL6RB_HUMAN PROTEIN (GP130) | |
1bqu[2] | E |
SO4
SULFATE ION[5 atoms] |
A | 100.0 /99.5 |
2 /2 |
IL6RB_HUMAN PROTEIN (GP130) | |
1bqu[1] | I |
SO4
SULFATE ION[5 atoms] |
B | 100.0 /99.5 |
2 /2 |
IL6RB_HUMAN PROTEIN (GP130) | |
1bqu[1] | J |
SO4
SULFATE ION[5 atoms] |
B | 100.0 /99.5 |
3 /3 |
IL6RB_HUMAN PROTEIN (GP130) | |
3l5h[1] | I |
SO4
SULFATE ION[5 atoms] |
A | 100.0 /100.0 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5h[1] | J |
SO4
SULFATE ION[5 atoms] |
A | 100.0 /100.0 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5h[1] | K |
SO4
SULFATE ION[5 atoms] |
A | 100.0 /100.0 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[1] | B |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 100.0 /100.0 |
2 /2 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[1] | C |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 100.0 /100.0 |
5 /5 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[1] | D |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 87.5 /100.0 |
8 /8 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[2] | E |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 100.0 /100.0 |
8 /8 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[1] | F |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 100.0 /100.0 |
6 /6 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[1] | G |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 100.0 /100.0 |
5 /5 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[1] | H |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 75.0 /100.0 |
4 /4 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[3] | I |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 100.0 /100.0 |
7 /7 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[1] | L |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 100.0 /100.0 |
5 /5 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[1] | M |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 100.0 /100.0 |
4 /4 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[1] | N |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 100.0 /100.0 |
3 /3 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[1] | P |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 83.3 /100.0 |
6 /6 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[1] | R |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 100.0 /100.0 |
5 /5 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[1] | S |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 100.0 /100.0 |
5 /5 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5i[1] | U |
EDO
1,2-ETHANEDIOL[4 atoms] |
A | 100.0 /100.0 |
2 /2 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8upa[1] | G |
PO4
PHOSPHATE ION[5 atoms] |
B | 100.0 /100.0 |
3 /4 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
1bqu[1] | F |
GOL
GLYCEROL[6 atoms] |
A | 100.0 /99.5 |
6 /6 |
IL6RB_HUMAN PROTEIN (GP130) | |
1bqu[2] | G |
GOL
GLYCEROL[6 atoms] |
A | 100.0 /99.5 |
8 /8 |
IL6RB_HUMAN PROTEIN (GP130) | |
1bqu[1] | L |
GOL
GLYCEROL[6 atoms] |
B | 100.0 /99.5 |
6 /6 |
IL6RB_HUMAN PROTEIN (GP130) | |
1bqu[1] | M |
GOL
GLYCEROL[6 atoms] |
B | 100.0 /99.5 |
4 /4 |
IL6RB_HUMAN PROTEIN (GP130) | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. |