Contact Molecules for Homologous Proteins | ||||
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PID | QueryLength | Homolgous Sequence in PDB | UniProt Query | TITLE |
10770 | 675 | 24 | Q8N3R9(PALS1_HUMAN) | RecName: Full=Protein PALS1 ;AltName: Full=MAGUK p55 subfamily member 5;AltName: Full=Membrane protein, palmitoylated 5 ;AltName: Full=Protein associated with Lin-7 1 ; |
QUERYSEQ |
MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLL LQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLY NANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWLR |
675 | region | name | description |
1-675 | CHAIN | /note="Protein PALS1" /id="PRO_0000094580" | |
120-177 | DOMAIN | /note="L27 1" | |
179-235 | DOMAIN | /note="L27 2" | |
256-336 | DOMAIN | /note="PDZ" | |
345-417 | DOMAIN | /note="SH3" | |
479-660 | DOMAIN | /note="Guanylate kinase-like" | |
1-345 | REGION | /note="Required for the correct localization of PALS1 and PATJ at cell-cell contacts and the normal formation of tight junctions and adherens junctions" | |
1-34 | REGION | /note="Disordered" | |
21-140 | REGION | /note="Interaction with PARD6B" | |
51-78 | REGION | /note="Disordered" | |
181-243 | REGION | /note="Interaction with LIN7C" | |
10-34 | COMPBIAS | /note="Basic and acidic residues" | |
57-78 | COMPBIAS | /note="Basic and acidic residues" | |
486-493 | BINDING | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" | |
1-469 | DISORDER | predicted by DISOPRED |
MONOMER | |||||||
675 | |||||||
pdb_id | a1 | identity[%]2 | description | ||||
4wsi | A | 100.0 | MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5 | ||||
3uit | D | 100.0 | INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, Protein lin-7 homolog B | ||||
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue. |
HETERO | |||||||
675 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
1y76[2] | A | MPDZ_RAT protein associated to tight junctions[62 aa] | B | 100.0 /100.0 |
4 /4 |
MPP5_HUMAN MAGUK p55 subfamily member 5 | |
1y76[2] | C | MPDZ_RAT protein associated to tight junctions[62 aa] | B | 100.0 /100.0 |
26 /26 |
MPP5_HUMAN MAGUK p55 subfamily member 5 | |
4uu5[1] | B | CRUM1_HUMAN PROTEIN CRUMBS HOMOLOG 1[14 aa] | A | 100.0 /100.0 |
13 /13 |
MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5 | |
4wsi[2] | C | CRB_DROME Protein crumbs[18 aa] | A | 100.0 /100.0 |
37 /37 |
MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5 | |
7m4r[1] | C | VEMP_SARS2 Envelope small membrane protein[9 aa] | A | 100.0 /100.0 |
11 /11 |
MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5 | |
7ntj[1] | B | VEMP_SARS Envelope small membrane protein[4 aa] | A | 100.0 /100.0 |
13 /13 |
MPP5_HUMAN MAGUK p55 subfamily member 5 | |
7ntj[1] | D | VEMP_SARS Envelope small membrane protein[7 aa] | C | 100.0 /100.0 |
13 /13 |
MPP5_HUMAN MAGUK p55 subfamily member 5 | |
7ntk[3] | C | VEMP_SARS2 Envelope small membrane protein[7 aa] | A | 100.0 /100.0 |
12 /12 |
MPP5_HUMAN MAGUK p55 subfamily member 5 | |
7ntk[1] | H | VEMP_SARS2 Envelope small membrane protein[6 aa] | F | 100.0 /100.0 |
14 /14 |
MPP5_HUMAN MAGUK p55 subfamily member 5 | |
7qcs[2] | C | VEMP_SARS2 Envelope small membrane protein[5 aa] | A | 100.0 /100.0 |
14 /14 |
PALS1_HUMAN Protein PALS1 | |
1vf6[4] | A | INADL_HUMAN PALS1-associated tight junction protein[58 aa] | C | 100.0 /91.7 |
20 /20 |
MPP5_MOUSE MAGUK p55 subfamily member 5 | |
1vf6[4] | B | INADL_HUMAN PALS1-associated tight junction protein[60 aa] | C | 50.0 /91.7 |
2 /2 |
MPP5_MOUSE MAGUK p55 subfamily member 5 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
COMPOUND | |||||||
675 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
4uu5[1] | K |
PUN
2,2,4,4,6,6,8-heptamethylnonane[16 atoms] |
A | 100.0 /100.0 |
2 /2 |
MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
METAL | |||||||
675 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
4uu5[3] | F |
CL
CHLORIDE ION[1 atoms] |
A | 100.0 /100.0 |
1 /1 |
MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5 | |
4uu5[1] | G |
CL
CHLORIDE ION[1 atoms] |
A | 100.0 /100.0 |
2 /2 |
MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5 | |
4uu5[1] | I |
CL
CHLORIDE ION[1 atoms] |
A | 100.0 /100.0 |
1 /1 |
MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5 | |
4uu5[1] | L |
CL
CHLORIDE ION[1 atoms] |
A | 100.0 /100.0 |
1 /1 |
MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5 | |
4uu5[1] | J |
NA
SODIUM ION[1 atoms] |
A | 100.0 /100.0 |
3 /3 |
MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
HOMO | |||||||
675 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
1y76[2] | D | MPP5_HUMAN MAGUK p55 subfamily member 5[60 aa] | B | 100.0 /100.0 |
6 /6 |
MPP5_HUMAN MAGUK p55 subfamily member 5 | |
7m4r[1] | B | MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5[270 aa] | A | 100.0 /100.0 |
20 /20 |
MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5 | |
7m4r[1] | A | MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5[360 aa] | B | 100.0 /100.0 |
19 /19 |
MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5 | |
7qcs[2] | B | PALS1_HUMAN Protein PALS1[98 aa] | A | 100.0 /100.0 |
9 /9 |
PALS1_HUMAN Protein PALS1 | |
7qcs[1] | E | PALS1_HUMAN Protein PALS1[82 aa] | A | 100.0 /100.0 |
2 /2 |
PALS1_HUMAN Protein PALS1 | |
7qcs[1] | A | PALS1_HUMAN Protein PALS1[97 aa] | E | 100.0 /100.0 |
1 /1 |
PALS1_HUMAN Protein PALS1 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
PRECIPITANT | |||||||
675 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
3uit[2] | E |
ACT
ACETATE ION[4 atoms] |
A | 100.0 /100.0 |
2 /3 |
INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P.. | |
3uit[4] | G |
ACT
ACETATE ION[4 atoms] |
A | 100.0 /100.0 |
1 /2 |
INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P.. | |
3uit[2] | H |
ACT
ACETATE ION[4 atoms] |
A | 100.0 /100.0 |
2 /5 |
INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P.. | |
3uit[2] | J |
ACT
ACETATE ION[4 atoms] |
A | 100.0 /100.0 |
3 /3 |
INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P.. | |
3uit[1] | K |
ACT
ACETATE ION[4 atoms] |
A | 100.0 /100.0 |
1 /5 |
INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P.. | |
3uit[1] | O |
ACT
ACETATE ION[4 atoms] |
B | 100.0 /100.0 |
1 /3 |
INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P.. | |
4uu6[1] | D |
ACT
ACETATE ION[4 atoms] |
A | 100.0 /100.0 |
1 /1 |
MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5 | |
4uu6[1] | B |
GOL
GLYCEROL[6 atoms] |
A | 100.0 /100.0 |
6 /6 |
MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5 | |
7ntk[1] | I |
FLC
CITRATE ANION[13 atoms] |
B | 100.0 /100.0 |
2 /2 |
MPP5_HUMAN MAGUK p55 subfamily member 5 | |
7ntk[2] | J |
EDO
1,2-ETHANEDIOL[4 atoms] |
B | 100.0 /100.0 |
1 /2 |
MPP5_HUMAN MAGUK p55 subfamily member 5 | |
7ntk[1] | K |
EDO
1,2-ETHANEDIOL[4 atoms] |
B | 100.0 /100.0 |
1 /1 |
MPP5_HUMAN MAGUK p55 subfamily member 5 | |
7ntk[1] | M |
EDO
1,2-ETHANEDIOL[4 atoms] |
D | 100.0 /100.0 |
5 /5 |
MPP5_HUMAN MAGUK p55 subfamily member 5 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. |