HOMCOS:Modeling Hetero Multimer

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This service generates a 3D model of hetero-multimer for given two query protein sequences, using a homologous protein complex 3D structure as a template

You can input a protein sequence by four ways: protein ID, amino acid sequence, PDB_ID + Chain_ID, or uploading your PDB file.

Protein A Protein B
Protein Sequence ID
(UniProt:ID/AC, RefSeq:protein_id)
(CDK5_HUMAN, NP_001157882.1) (CCNB1_HUMAN, NP_114172.1)
Amino acid sequence (one letter)

PDB PDB_ID:(1fin, 4hhb,...) CHAIN_ID:(A, B, ...) PDB_ID:(1fin, 4hhb,...) CHAIN_ID:(A, B, ...)
Upload your PDB file

min Nresidue_contact_aligned (minNca)
min Ratio of residue_contact_aligned (minRca) (%)
Use precalculated BLAST: (precalc_blt) no yes

The sequence search is performed by BLAST.
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