HOMCOS:Modeling Hetero Multimer

This service generates a 3D model of hetero-multimer for given two query protein sequences, using a homologous protein complex 3D structure as a template

You can input a protein sequence by four ways: protein ID, amino acid sequence, PDB_ID + Chain_ID, or uploading your PDB file.

Protein A Protein B

Protein Sequence ID
(UniProt:ID/AC, RefSeq:protein_id) (CDK5_HUMAN, NP_001157882.1) (CCNB1_HUMAN, NP_114172.1)

Amino acid sequence (one letter)

PDB PDB_ID:(1fin, 4hhb,...) CHAIN_ID:(A, B, ...) PDB_ID:(1fin, 4hhb,...) CHAIN_ID:(A, B, ...)

Upload your PDB file

E-value:
min Nresidue_contact_aligned (minNca)
min Ratio of residue_contact_aligned (minRca) (%)
Use precalculated BLAST: (precalc_blt) no yes

The sequence search is performed by BLAST.
Comments and Questions to :

Go to HOMCOS top page

	Protein A	Protein B
Protein Sequence ID (UniProt:ID/AC, RefSeq:protein_id)	(CDK5_HUMAN, NP_001157882.1)	(CCNB1_HUMAN, NP_114172.1)
Amino acid sequence (one letter)
PDB	PDB_ID:(1fin, 4hhb,...) CHAIN_ID:(A, B, ...)	PDB_ID:(1fin, 4hhb,...) CHAIN_ID:(A, B, ...)
Upload your PDB file